“…Here we show that non-canonical RNA bases, which are found today in transfer and ribosomal RNAs(6,7), and which are considered to be relics of the RNA world(8–12), are able to establish peptide synthesis directly on RNA. The discovered chemistry creates complex peptide-decorated RNA chimeric molecules, which suggests the early existence of an RNA–peptide world(13) from which ribosomal peptide synthesis(14) may have emerged(15,16). …”
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“…The characteristic photophysical properties of these novel naphthyl-decorated oxacalix[m]arene[n]pyrimidines broaden their application field, and the stable host–guest system with fullerene can be applied to supramolecular chemistry.…”
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“…[Image: see text] Recent discoveries of a range of single-crystal optical actuators are feeding a new form of materials chemistry, given their broad range of potential applications, from light-induced molecular motors to light sensors and optical-memory media. …”
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“…Anthropometric indexes, blood and urine chemistry, body composition by DEXA, muscle strength by handgrip test and Short Physical Performance Battery (SPPB) were assessed at baseline and at the end of the treatment. …”
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“…However, with total automation, the number of tests performed per single worker has increased to an average of 1.4 and 3.7 times with total automation in the clinical chemistry and serology sections, respectively (p ≤ 0.001). …”
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“…Such results serve as baseline for understanding the chemistry of these species and performing strict correlation between metabolite and activity where a lack of information in this regard is observed.…”
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“…This proposed 3D printing-on-membrane approach, elegantly bridging the fields of microfluidics and membrane science, is instrumental to many other applications in energy, sensing, analytical chemistry and biomedical engineering.…”
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“…Bacterioplankton molecular ecological network stability and robustness were higher on average in the upper reaches (where there is lower intensity of human activity), but a human activity intensity increase of about 10%/10% can reduce co-occurrence network stability of bacterioplankton communities by an average of 0.62%/0.42% in the dry and wet season, respectively. In addition, water chemistry (especially NO(3)(–)-N and Cl(–)) contributed more to explaining community assembly (especially the composition) than geographic distance and land use in the dry season, while the bacterioplankton community (especially the bacterioplankton network) was more influenced by distance (especially the length of rivers and dendritic streams) and land use (especially forest regions) in the wet season. …”
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“…Studies on spheroids with different receptor‐expression, used as surrogates of the tumors' avascular regions, demonstrated that our delivery strategy is valid even for as low as 1+ (ImmunoHistoChemistry score) PSMA‐levels. The findings presented herein may hold clinical promise for those established tumors not being effectively eradicated by current α‐particle radiotherapies.…”
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“…Significant progress has been demonstrated in the development of bifunctional oxide-zeolite catalyst concept to tackle the selectivity challenge in syngas chemistry. Despite general recognition on the importance of defect sites of metal oxides for CO/H(2) activation, the actual structure and catalytic roles are far from being well understood. …”
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“…Intimately connected to the rule of life, chirality remains a long-time fascination in biology, chemistry, physics and materials science. Chiral structures, e.g., nucleic acid and cholesteric phase developed from chiral molecules are common in nature and synthetic soft materials. …”
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“…Variable length polyglutamylation of primary sequence glutamyl residues have been mapped with a multitude of protein chemistry and proteomics approaches. Although polyglutamylation was initially considered a tubulin-specific modification, the recent studies have uncovered a calmodulin-dependent glutamylase, SidJ. …”
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“…The role of PhN(3) and NaN(3) in copper-free click chemistry is exemplified for hyperpolarized triazole (T(1) < 10 s) formation when they react with a strained alkyne. …”
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“…Furthermore, the hydrophobic core of the membranes favors the reactivity of nitrogen oxides with other molecules, making membranes an important factor in the chemistry of nitrosative stress. Since bacteria are often exposed to endogenous or exogenous nitrogen oxides, they have acquired protection mechanisms against the deleterious effects of these molecules. …”
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“…[Image: see text] N-Triphos derivatives (NP(3)(R), R = alkyl, aryl) and asymmetric variants (NP(2)(R)X(R′), R′ = alkyl, aryl, X = OH, NR(2), NRR′) are an underexplored class of tuneable, tripodal ligands in relation to the coordination chemistry of Re and Tc for biomedical applications. …”
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“…Fluorescence spectroscopy is among the most used techniques in analytical chemistry laboratories, mainly due to its high sensitivity and simplicity. …”
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“…Core–shell nanoparticles have attracted much attention in recent years due to their unique properties and their increasing importance in many technological and consumer products. However, the chemistry of nanoparticles is still rarely investigated in comparison to their size and morphology. …”
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“…To establish a predictive peripheral biomarker profile based on a larger cohort of rhesus macaques (RM), we analyzed results pertaining to peripheral blood serum chemistry and cell counts from RMs that were experimentally exposed to Mtb in our prior studies and characterized as having either developed active TB (ATB) disease or latent TB infection (LTBI). …”
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“…CGNPs were functionalized with polyethylene glycol (PEG) to form PEGylated GNP (PGNP). EDC/SNHS chemistry is used to activate the –COOH group of the PEG to make it suitable for conjugation with antibodies corresponding to exosomal surface proteins. …”
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