“…Here we report active-site mutants of HisG(S) with impaired reaction chemistry which can be allosterically restored by HisZ despite the HisZ:HisG(S) interface lying ~20 Å away from the active site. …”
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“…The American Association of Pharmaceutical Scientists (AAPS) Chemistry, Manufacturing, and Controls (CMC) Community hosted two virtual panel discussions focusing on several novel regulatory review pathways for innovative oncology products: Real-Time Oncology Review (RTOR), Project Orbis, and the Product Quality Assessment Aid (PQAAid). …”
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“…The optimization of depolymerization conditions permitted 100% depolymerization within 5 min of reaction at 120 °C using 30 mL of KMH solution per g of composite. The green chemistry metrics reflect that our system is more efficient than most of the depolymerization systems found in the literature. …”
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“…The global and local descriptors, which are the underpinnings of Conceptual Density FunctionalTheory (CDFT) have beenpredicted through successful model chemistry, hoping that they could be of help in the comprehension of the chemical reactivity properties of the molecular systems considered in this study.…”
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“…Circular polarized light-dependent anomalous bulk photovoltaic effect - a steady anomalous photovoltaic current can be manipulated by changing the light helicity, is an increasingly interesting topic in contexts ranging from physics to chemistry. Herein, circular polarized light-dependent anomalous bulk photovoltaic effect is presented in achiral hybrid perovskites, (4-AMP)BiI(5) (ABI, 4-AMP is 4-(aminomethyl)piperidinium), breaking conventional realization that it can only happen in chiral species. …”
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“…The EU‐FORA fellowship was a great opportunity for the fellow to expand his professional network and increase his expertise in food safety by gaining new skills in chemical risk assessment, risk–benefit assessment and analytical chemistry.…”
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“…Outcomes (significant decrease of platelets, hemoglobin levels and neutrophils) were assessed 1 month later, considering their within-subject biological coefficient of variation, published by the European Federation of Clinical Chemistry and Laboratory Medicine. A total of 9 patients (33 treatment sessions) were included. …”
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“…The kinetic study of catalytic CO(2) desorption was also carried out. CO(2) desorption chemistry, catalyst characterization, and structure–function relationships were investigated to reveal the underlying mechanisms. …”
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“…Overall, the findings of this study attributed 3-methyleneisoindolinone chemistry and efficacy evaluation and corroborated their anticancer potential against HNSCC. …”
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“…To achieve the full potential of these covalent adaptable networks (CANs), it is essential to understand—and control—the underlying chemistry and physics of the dynamic covalent bonds that undergo bond exchange reactions in the network. …”
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“…[Image: see text] The fate of biomolecules in the environment depends in part on understanding the surface chemistry occurring at the biological–geochemical (bio–geo) interface. …”
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“…The anti-solvent used for the post-treatment of FAPbI(3) PQD solid films significantly affects the surface chemistry of the PQDs, and thus the vacancies caused by surface ligand removal inhibit the optoelectronic properties and stability of PQDs. …”
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“…Consequently, the detailed evaluation on the role of the complex associations between weathering and physicochemical properties of plastics should help us gain a better knowledge with respect to the transport, behavior, fate, and toxicological chemistry of plastics along with the proper tactics for their sustainable remediation.…”
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“…The current study aimed to investigate the dietary supplementation effect of corn silk (CS) on performance and blood chemistry of brown and white-feathered quails during the grower and layer periods. …”
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“…Mucormycosis, also known as Zygomycosis, is a disease caused by invasive fungi, predominantly Rhizopus species belonging to the Order of Mucorales. Seeing from the chemistry perspective, heterocyclic compounds with an "azole" moiety are widely employed as antifungal agent for minimising the effect of mucormycosis as a prescribed treatment. …”
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“…Our findings build an interesting platform for medicinal chemistry-guided derivatization approaches followed by deeper phenotypical characterization in vitro and in vivo with the aim of developing highly potent hRSV drugs.…”
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“…Google Earth Engine empowered cloud computing based remote sensing is used and the results provide a testbed for climate sensitivity experiments and validation of chemistry-climate models. Additionally, Google Earth Engine based apps have been developed to visualize the changes in a real-time fashion.…”
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“…The changes observed are driven by modification of the surface chemistry and the presence of nickel, causing grain size reduction, solid solution strengthening and dispersion strengthening of the treated layer by the nanoparticles. …”
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“…Increasing concerns regarding the use of toxic elements like cadmium and lead, and hazardous organic solvents during QD synthesis have meanwhile triggered the search for heavy-metal free QDs using green chemistry syntheses methods. Interesting candidates are ternary AgInS(2) (AIS) QDs that exhibit broad photoluminescence (PL) bands, large effective Stokes shifts, high PL quantum yields (PL QYs), and long PL lifetimes, which are particularly beneficial for applications such as bioimaging, white light-emitting diodes, and solar concentrators. …”
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