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  1. 88201
    por Hu, QH, Zavarin, M, Rose, TP
    Publicado 2008
    “…Under atmospheric (oxidizing) conditions, radionuclide distribution coefficients varied with the mineralogic composition of the sorbent and the water chemistry. Under reducing conditions, distribution coefficients showed marked increases for (99)Tc (from 1.22 at oxidizing to 378 mL/g at mildly reducing conditions) and (237)Np (an increase from 4.6 to 930 mL/g) in devitrified tuff, but much smaller variations in alluvium, carbonate rock, and zeolitic tuff. …”
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    Effect of reducing groundwater on the retardation of redox-sensitive radionuclides
  2. 88202
    “…Furthermore, since the chemistry of many ferrichromes is known, the biochemical and structural 'rules' guiding NRPS substrate choice can be addressed using protein structural modeling and evolutionary approaches. …”
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    Module evolution and substrate specificity of fungal nonribosomal peptide synthetases involved in siderophore biosynthesis
  3. 88203
    “…An alternative to this medicinal chemistry approach is a systems biology based strategy that seeks to amplify selectively the anti-inflammatory activity of very low dose glucocorticoid in immune cells without modulating alternative cellular networks that mediate glucocorticoid toxicity. …”
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    Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug
  4. 88204
    “…This approach, therefore builds, upon the progress made in computational chemistry to achieve more accurate in silico docking and in information technology to design and operate large scale grid infrastructures. …”
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    WISDOM-II: Screening against multiple targets implicated in malaria using computational grid infrastructures
  5. 88205
    “…BACKGROUND: Chemogenomics is an emerging inter-disciplinary approach to drug discovery that combines traditional ligand-based approaches with biological information on drug targets and lies at the interface of chemistry, biology and informatics. The ultimate goal in chemogenomics is to understand molecular recognition between all possible ligands and all possible drug targets. …”
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    A chemogenomics view on protein-ligand spaces
  6. 88206
    “…Fine PM [aerodynamic diameter ≤ 2.5 μm (PM(2.5))] exposure based on a small-scale dispersion and chemistry transport model was assigned to each home address. …”
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    Chronic Residential Exposure to Particulate Matter Air Pollution and Systemic Inflammatory Markers
  7. 88207
    “…Applying isobaric peptide tagging chemistry (iTRAQ) combined with two-dimensional LC and MALDI-TOF/TOF mass spectrometry, we were able to identify several thousand proteins in membrane-enriched fractions of which 1460 were extracted as quantifiable proteins (isoform- and species-specific and present in more than one sample). …”
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    iTRAQ-based Proteomics Profiling Reveals Increased Metabolic Activity and Cellular Cross-talk in Angiogenic Compared with Invasive Glioblastoma Phenotype
  8. 88208
    “…Recently, the basic AlphaScreen technology was extended in that the chemistry of the Acceptor bead was modified such that emitted light is more intense and spectrally defined, thereby markedly reducing interference from biological fluid matrices (such as trace hemolysis in serum and plasma). …”
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    The Use of AlphaScreen Technology in HTS: Current Status
  9. 88209
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    Structural studies on encapsulation of tetrahedral and octahedral anions by a protonated octaaminocryptand cage
  10. 88210
    “…We performed anthropometric measurements, fat computed tomography (CT), and blood sampling to determine blood chemistry and levels of hsCRP, gonadotropins, testosterone, and sex-hormone binding globulin. …”
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    Serum C-Reactive Protein Levels in Normal-Weight Polycystic Ovary Syndrome
  11. 88211
    “…The results suggest that PM of different size-specific chemistry might be associated with different toxicologic mechanisms in cardiac and pulmonary tissues.…”
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    Comparative Toxicity of Size-Fractionated Airborne Particulate Matter Collected at Different Distances from an Urban Highway
  12. 88212
    “…The attributes of TiO(2 )that have been identified as being most likely to drive the observed toxicity include particle size (and therefore surface area), crystallinity (and photocatalytic activity), surface chemistry, and particle aggregation/agglomeration tendency. …”
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    Identification of the mechanisms that drive the toxicity of TiO(2 )particulates: the contribution of physicochemical characteristics
  13. 88213
    por Hawkes, Wayne Chris, Alkan, Zeynep
    Publicado 2010
    “…The unique chemistry of oxygen has been both a resource and threat for life on Earth for at least the last 2.4 billion years. …”
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    Regulation of Redox Signaling by Selenoproteins
  14. 88214
    “…Safety was assessed by complete blood cell count, erythrocyte sedimentation rate, blood chemistry, urine analysis, PA chest film, brain computed tomography, otologic examination, and vital signs. …”
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    Bojungikgitang and banhabaekchulchonmatang in adult patients with tinnitus, a randomized, double-blind, three-arm, placebo-controlled trial - study protocol
  15. 88215
    por Petrov, Viacheslav A, Marshall, Will
    Publicado 2010
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    Acid catalyzed cyclodimerization of 2,2-bis(trifluoromethyl)-4-alkoxy-oxetanes and -thietanes. Synthesis of 2,2,6,6-tetrakis(trifluoromethyl)-4,8-dialkoxy-1,5-dioxocanes and 3,3,7,7-tetrakis(trifluoromethyl)-9-oxa-2,6-dithia-bicyclo[3.3.1]nonane
  16. 88216
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    Synthesis and crossover reaction of TEMPO containing block copolymer via ROMP
  17. 88217
    “…C-reactive protein (CRP) was measured using a clinical chemistry analyser. Plasma concentrations of protein C and von Willebrand factor (vWF) were measured using enzyme-linked fluorescent assays (ELFA). …”
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    Tourniquet-Applied Upper Limb Orthopaedic Surgery Results in Increased Inflammation and Changes to Leukocyte, Coagulation and Endothelial Markers
  18. 88218
    “…After 90 days of exposure, clinical chemistry, hematology, histopathology, and silver distribution were studied. …”
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    Subchronic oral toxicity of silver nanoparticles
  19. 88219
    “…Patients were evaluated for echocardiographic data, blood chemistry and ACA. Two-dimensional and Doppler echocardiographic examinations were performed in all patients within the first week and at 14 days after MI. …”
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    Risk factors for development of left ventricular thrombus after first acute anterior myocardial infarction-association with anticardiolipin antibodies
  20. 88220
    “…Over the years development of selective estrogen receptor (ER) ligands has been of great concern to researchers involved in the chemistry and pharmacology of anticancer drugs, resulting in numerous synthesized selective ER subtype inhibitors. …”
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    In Silico Prediction of Estrogen Receptor Subtype Binding Affinity and Selectivity Using Statistical Methods and Molecular Docking with 2-Arylnaphthalenes and 2-Arylquinolines
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