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  1. 88221
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    Oxalyl retro-peptide gelators. Synthesis, gelation properties and stereochemical effects
  2. 88222
    “…Twenty-four hours later, arterial pressure, heart rate, and baroreflex function were measured in conscious and one day later in anesthetized conditions. Basic blood chemistry and circulating markers of cardiac injury were also measured. …”
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    High sugar intake exacerbates cardiac reperfusion injury in perinatal taurine depleted adult rats
  3. 88223
    “…METHODS: Three SNPs with prior evidence of association with susceptibility to PsV were genotyped in 1057 patients with PsA using Sequenom iPlex chemistry and genotype frequencies compared with data available for 5575 healthy controls. …”
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    Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis
  4. 88224
    “…CONCLUSIONS/SIGNIFICANCE: We demonstrated that our virtual-screening protocol was successful in identifying lead compounds for developing new inhibitors for hIKK-2, a target of great interest in medicinal chemistry. Additionally, all the tools developed during the current study (i.e., the homology model for the hIKK-2 kinase domain and the pharmacophore) will be made available to interested readers upon request.…”
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    Identification of Human IKK-2 Inhibitors of Natural Origin (Part I): Modeling of the IKK-2 Kinase Domain, Virtual Screening and Activity Assays
  5. 88225
    “…BACKGROUND: The new ruthenium(II)-arene complex, which bearing a carborane unit, ruthenium and ferrocenyl functional groups, has a novel versatile synthetic chemistry and unique properties of the respective material at the nanoscale level. …”
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    Nanoscaled carborane ruthenium(II)-arene complex inducing lung cancer cells apoptosis
  6. 88226
    por Morrison, Wendy E., Hay, Mark E.
    Publicado 2011
    “…Tests of plant traits indicated that the crayfish responded primarily to plant structure, the apple snails primarily to plant chemistry, and that plant protein concentration played no detectable role. …”
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    Herbivore Preference for Native vs. Exotic Plants: Generalist Herbivores from Multiple Continents Prefer Exotic Plants That Are Evolutionarily Naïve
  7. 88227
    “…METHODS: The medical records from 66 patients submitted to gastroplasty were reviewed. Their chemistry profile, abdominal ultrasound (US) and liver biopsy done during the surgical procedure were analyzed. …”
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    New clinical score to diagnose nonalcoholic steatohepatitis in obese patients
  8. 88228
    “…Sample preparation and extraction, detection chemistry, assay reproducibility, and limit of detection were compared to a previously published SYBR Green rt-qPCR used in a malaria vaccine clinical trial. …”
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    A real-time, quantitative PCR method using hydrolysis probes for the monitoring of Plasmodium falciparum load in experimentally infected human volunteers
  9. 88229
    “…Increasing physical activity may block negative thoughts, increase social contact, positively influence brain chemistry and improve both physical and mental health. …”
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    Reducing psychological distress and obesity in Australian farmers by promoting physical activity
  10. 88230
    por Jeliazkova, Nina, Jeliazkov, Vedrin
    Publicado 2011
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    AMBIT RESTful web services: an implementation of the OpenTox application programming interface
  11. 88231
    “…The results revealed observable effects of oil on soil physico-chemistry, plant growth and nodulation as well as on densities of heterotrophic, hydrocarbonoclastic and nitrogen fixing bacteria. …”
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    Fate of Nitrogen-Fixing Bacteria in Crude Oil Contaminated Wetland Ultisol
  12. 88232
    “…We originated and evaluated a novel one-step biomarker and histology preservative (BHP) chemistry that stabilizes signaling protein phosphorylation and retains formalin-like tissue histomorphology with equivalent immunohistochemistry in a single paraffin block. …”
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    One-Step Preservation of Phosphoproteins and Tissue Morphology at Room Temperature for Diagnostic and Research Specimens
  13. 88233
    “…In the last two decades, our team has collaborated with different medicinal chemistry groups to develop preclinical studies for CD and investigate the in vitro and in vivo efficacy, toxicity, selectivity, and parasite targets of different classes of natural and synthetic compounds. …”
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    Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones
  14. 88234
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    Geophysical monitoring and reactive transport modeling of ureolytically-driven calcium carbonate precipitation
  15. 88235
    “…Knowledge of this spatial and temporal variation in seawater chemistry allows us to improve the design of OA experiments: we can test organisms with a priori expectations of their tolerance guardrails, based on their natural range of exposure. …”
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    High-Frequency Dynamics of Ocean pH: A Multi-Ecosystem Comparison
  16. 88236
    por Nguyen, Minhtri K, Kao, Liyo, Kurtz, Ira
    Publicado 2011
    “…Our results provide further important evidence that one can mathematically model the chemistry of acid-base phenomenology without relying on electroneutrality (Stewart formulation) considerations.…”
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    Defining the buffering process by a triprotic acid without relying on stewart-electroneutrality considerations
  17. 88237
    “…In electrophysiological experiments performed on Xenopus laevis oocytes and mammalian cells, VU573 inhibited Kir3.1/3.2 (neuronal GIRK) and Kir3.1/3.4 (cardiac GIRK) channels with equal potency and preferentially inhibited GIRK, Kir2.3, and Kir7.1 over Kir1.1 and Kir2.1.Tl(+) flux assays were established for Kir2.3 and the M125R pore mutant of Kir7.1 to support medicinal chemistry efforts to develop more potent and selective analogs for these channels. …”
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    Discovery, Characterization, and Structure–Activity Relationships of an Inhibitor of Inward Rectifier Potassium (Kir) Channels with Preference for Kir2.3, Kir3.X, and Kir7.1
  18. 88238
    “…Urban background exposure to PM with aerodynamic diameter ≤ 2.5 μm (PM(2.5)) and ≤ 10 μm (PM(10)) was assessed with a dispersion and chemistry transport model. We used generalized additive models, adjusting for short-term PM, meteorology, traffic proximity, and individual risk factors. …”
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    Long-Term Urban Particulate Air Pollution, Traffic Noise, and Arterial Blood Pressure
  19. 88239
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    PubChem3D: a new resource for scientists
  20. 88240
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    An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential
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