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Química
313
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47
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41
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Espectroscopia de resonancia magnética nuclear
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88521por Leonova, Elena I., Sadovnikova, Elena S., Shaykhutdinova, Elvira R., Galzitskaya, Oxana V., Murashev, Arkady N., Solonin, Alexandr S.“…METHODS: ApoE knockout (ApoE(-/-)) mice as a model of atherosclerosis were used. Plasma chemistry parameters were estimated by automatic biochemical analyzer. …”
Publicado 2017
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88522“…In this study, we disentangle the impact of elevation and soil chemistry on diversity and distribution of rotifers, nematodes and tardigrades and their most frequent feeding strategies (microbial filter-feeders, bacterivores, fungivores, root-fungal feeders, omnivores) along two contrasting altitudinal gradients in Indian NW Himalaya (Zanskar transect from 3805 to 4714 m a.s.l.) and southwestern Tibet (Tso Moriri transect from 4477 to 6176 m a.s.l.), using a combination of multivariate analysis, variation partitioning and generalized additive models. …”
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88523por Gorelenkova Miller, Olga, Cole, Kyle S., Emerson, Corey C., Allimuthu, Dharmaraja, Golczak, Marcin, Stewart, Phoebe L., Weerapana, Eranthie, Adams, Drew J., Mieyal, John J.“…Exploiting the alkyne moiety of CWR-J02, we used click chemistry to link biotin azide to CWR-J02-adducted proteins, isolating them with streptavidin beads. …”
Publicado 2017
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88524por Adiya, Tsolmon, Johnson, Cari L., Loewen, Mark A., Ritterbush, Kathleen A., Constenius, Kurt N., Dinter, Cory M.“…Stratigraphic juxtaposition of nearshore bioherms and the bounding distal oil-shale facies suggests that the bioherms developed in an underfilled lake basin, resulting from an abrupt and short-lived lake desiccation event. Lake chemistry is believed to have been relatively alkaline, saline to hypersaline, and rich in Ca, Mg, and HCO(3) ions. …”
Publicado 2017
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88525por Di Iorio, Biagio, Di Micco, Lucia, Bruzzese, Dario, Nardone, Luca, Russo, Luigi, Formisano, Pietro, D’Esposito, Vittoria, Russo, Domenico“…Total study duration was 1 year. Routine chemistry, bacterial count, endotoxin levels in dialysis-water as well as blood levels of pro- and anti-inflammatory cytokines, human serum amyloid A, C-reactive protein and fraction 5 of complement were measured. …”
Publicado 2017
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88526“…Effects of land use and soil chemistry on the functional diversity of nematodes were demonstrated and a combination of environmental factors accounts for the low functional value of Scots Pine forest soils in comparison to the high functional value of heathland soils, whereas human factors account for the low functional and chemical values of arable fields. …”
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88527por Ooi, Chin Chun, Mantalas, Gary L., Koh, Winston, Neff, Norma F., Fuchigami, Teruaki, Wong, Dawson J., Wilson, Robert J., Park, Seung-min, Gambhir, Sanjiv S., Quake, Stephen R., Wang, Shan X.“…In addition, while mRNA-seq data is typically only used for gene expression analysis of transcriptomic data, we demonstrate the use of full-length mRNA-seq chemistries like Smart-seq2 to facilitate variant analysis of expressed genes. …”
Publicado 2017
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88528por Hromić-Jahjefendić, Altijana, Jajčanin Jozić, Nina, Kazazić, Saša, Grabar Branilović, Marina, Karačić, Zrinka, Schrittwieser, Jörg H., Das, Krishna Mohan Padmanabha, Tomin, Marko, Oberer, Monika, Gruber, Karl, Abramić, Marija, Tomić, Sanja“…Here, we report the characterization of DPP III using molecular biology, biochemical, biophysical and computational chemistry methods. In addition to the expected evolutionarily conserved regions of all DPP III family members, PgDPP III possesses a C-terminal extension containing an Armadillo (ARM) type fold similar to the AlkD family of bacterial DNA glycosylases, implicating it in alkylation repair functions. …”
Publicado 2017
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88529por Shim, Man Kyu, Yoon, Hong Yeol, Lee, Sangmin, Jo, Mun Kyeong, Park, Jooho, Kim, Jong-Ho, Jeong, Seo Young, Kwon, Ick Chan, Kim, Kwangmeyung“…Importantly, the azido groups on the apoptotic tumor cells could be visualized with Cy5.5-conjugated dibenzylcyclooctyne (DBCO-Cy5.5) via bioorthogonal click chemistry in vitro cell culture condition and in vivo tumor-bearing mice. …”
Publicado 2017
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88530por Tozin, Luiz Ricardo dos Santos, Mayo Marques, Marcia Ortiz, Maria Rodrigues, Tatiane“…We investigated the effect of leaf-cutter ant attack on the density of the glandular trichomes and on the chemistry of the VOCs released from leaves of O. gratissimum. …”
Publicado 2017
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88531“…Our findings indicate that Fe and Mn chemistry is influenced by sustained reactions of Fe(II) with Mn/Fe oxides. …”
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88532“…The aim of this in vitro study was to endow an implant surface with favorable biological properties by the dual modification of surface chemistry and nanostructured topography. The application of a nanostructured titanium dioxide (TiO(2)) coating on Ti-based implants has been proposed as a potential way to enhance tissue-implant interactions while inhibiting bacterial colonization simultaneously due to its chemical stability, biocompatibility, and antimicrobial properties. …”
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88533por Santucci, Matteo, Spyrakis, Francesca, Cross, Simon, Quotadamo, Antonio, Farina, Davide, Tondi, Donatella, De Luca, Filomena, Docquier, Jean-Denis, Prieto, Ana Isabel, Ibacache, Claudia, Blázquez, Jesús, Venturelli, Alberto, Cruciani, Gabriele, Costi, Maria Paola“…A multiligand set of boronic acid (BA) β-lactamase inhibitors was obtained using covalent molecular modeling, synthetic chemistry, enzyme kinetics and antibacterial susceptibility testing. …”
Publicado 2017
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88534por Xia, Ding, Lou, Weiwei, Fung, Kar-Ming, Wolley, Cole L., Suhail, Mahmoud M., Lin, Hsueh-Kung“…His liver and kidney functions are considered to be normal based on blood chemistry tests. This index case suggests that BSGRH may have cancer chemopreventive effects on UCC. …”
Publicado 2016
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88535por Zhang, Feng, Shu, Jin-Ling, Li, Ying, Wu, Yu-Jing, Zhang, Xian-Zheng, Han, Le, Tang, Xiao-Yu, Wang, Chen, Wang, Qing-Tong, Chen, Jing-Yu, Chang, Yan, Wu, Hua-Xun, Zhang, Ling-Ling, Wei, Wei“…Paeoniflorin-6′-O-benzene sulfonate (code: CP-25) was the chemistry structural modifications of Paeoniflorin (Pae). …”
Publicado 2017
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88536“…Evaluated features for biologics with established E–R relationships for efficacy and/or safety and MTD include an IIV for the CL and various other covariates including demographic factors, disease factors, blood chemistry, or immunogenicity. RESULTS: Five therapies were identified with documented E–R relationships for both efficacy and safety including, Yervoy(®)(ipilimumab), Zaltrap(®) (ziv-aflibercept), Portrazza(®) (necitumumab), Adcetris(®) (brentuximab-vedotin), and Blincyto(®) (blinatumomab). …”
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88537por Miyazaki, Junichi, Kawagucci, Shinsuke, Makabe, Akiko, Takahashi, Ayu, Kitada, Kazuya, Torimoto, Junji, Matsui, Yohei, Tasumi, Eiji, Shibuya, Takazo, Nakamura, Kentaro, Horai, Shunsuke, Sato, Shun, Ishibashi, Jun-ichiro, Kanzaki, Hayato, Nakagawa, Satoshi, Hirai, Miho, Takaki, Yoshihiro, Okino, Kyoko, Watanabe, Hiromi Kayama, Kumagai, Hidenori, Chen, Chong“…Depth is a significant factor in determining fluid temperature and chemistry, as well as biological composition. However, due to the narrow depth range of known sites, the actual influence of depth here has been poorly resolved. …”
Publicado 2017
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88538por Wishart, David S, Feunang, Yannick Djoumbou, Marcu, Ana, Guo, An Chi, Liang, Kevin, Vázquez-Fresno, Rosa, Sajed, Tanvir, Johnson, Daniel, Li, Carin, Karu, Naama, Sayeeda, Zinat, Lo, Elvis, Assempour, Nazanin, Berjanskii, Mark, Singhal, Sandeep, Arndt, David, Liang, Yonjie, Badran, Hasan, Grant, Jason, Serra-Cayuela, Arnau, Liu, Yifeng, Mandal, Rupa, Neveu, Vanessa, Pon, Allison, Knox, Craig, Wilson, Michael, Manach, Claudine, Scalbert, Augustin“…Many other important improvements in the content, the interface, and the performance of the HMDB website have been made and these should greatly enhance its ease of use and its potential applications in nutrition, biochemistry, clinical chemistry, clinical genetics, medicine, and metabolomics science.…”
Publicado 2018
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88539por Alandijany, Thamir, Roberts, Ashley P. E., Conn, Kristen L., Loney, Colin, McFarlane, Steven, Orr, Anne, Boutell, Chris“…Here we utilize 5-Ethynyl-2’-deoxyuridine (EdU) labelling of herpes simplex virus 1 (HSV-1) DNA in combination with click chemistry to examine the sequential recruitment of host immune regulators to infecting viral genomes under low multiplicity of infection conditions. …”
Publicado 2018
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88540por Orellana, Adelina, García-González, Vicente, López, Rosa, Pascual-Guiral, Sonia, Lozoya, Estrella, Díaz, Julia, Casals, Daniel, Barrena, Antolín, Paris, Stephane, Andrés, Miriam, Segarra, Victor, Vilella, Dolors, Malhotra, Rajneesh, Eastwood, Paul, Planagumà, Anna, Miralpeix, Montserrat, Nueda, Arsenio“…This study illustrates the potential of phenotypic drug discovery to complement target based approaches by providing new chemistry and biology leads.…”
Publicado 2018
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