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  1. 88541
    “…The promising pharmacokinetic profile and significant in vivo efficacy observed from our HTS hits highlight the utility of our two-step phenotypic screening strategy and strongly suggest that medicinal chemistry optimization of these newly identified scaffolds will lead to promising candidates for an orally available anti-parasitic drug.…”
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    Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening
  2. 88542
    “…Passing-Bablok regression of plasma concentrations by CE-MS on serum concentrations by standard clinical chemistry assays was conducted for creatinine and uric acid. …”
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    Reliability of plasma polar metabolite concentrations in a large-scale cohort study using capillary electrophoresis-mass spectrometry
  3. 88543
    por Nourse, Marilyn B., Engel, Kate, Anekal, Samartha G., Bailey, Jocelyn A., Bhatta, Pradeep, Bhave, Devayani P., Chandrasekaran, Shekar, Chen, Yutao, Chow, Steven, Das, Ushati, Galil, Erez, Gong, Xinwei, Gessert, Steven F., Ha, Kevin D., Hu, Ran, Hyland, Laura, Jammalamadaka, Arvind, Jayasurya, Karthik, Kemp, Timothy M., Kim, Andrew N., Lee, Lucie S., Liu, Yang Lily, Nguyen, Alphonso, O'Leary, Jared, Pangarkar, Chinmay H., Patel, Paul J., Quon, Ken, Ramachandran, Pradeep L., Rappaport, Amy R., Roy, Joy, Sapida, Jerald F., Sergeev, Nikolay V., Shee, Chandan, Shenoy, Renuka, Sivaraman, Sharada, Sosa‐Padilla, Bernardo, Tran, Lorraine, Trent, Amanda, Waggoner, Thomas C., Wodziak, Dariusz, Yuan, Amy, Zhao, Peter, Young, Daniel L., Robertson, Channing R., Holmes, Elizabeth A.
    Publicado 2018
    “…The miniLab can detect analytes in blood using multiple methods, including molecular diagnostics, immunoassays, clinical chemistry, and hematology. Analytical performance results show that our qualitative Zika virus assay has a limit of detection of 55 genomic copies/ml. …”
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    Engineering of a miniaturized, robotic clinical laboratory
  4. 88544
    “…Blood and urine samples were collected for evaluation of cobalt concentration, CBC and clinical chemistry, and hormone concentrations. RESULTS: All mares displayed pawing, nostril flaring, muscle tremors, and straining after CoCl(2) infusion. …”
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    Effect of Intravenous Administration of Cobalt Chloride to Horses on Clinical and Hemodynamic Variables
  5. 88545
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    Encapsulation of Cadmium Selenide Nanocrystals in Biocompatible Nanotubes: DFT Calculations, X‐ray Diffraction Investigations, and Confocal Fluorescence Imaging
  6. 88546
    “…Next, we demonstrate the sensitivity of detection of low-frequent single-nucleotide mtDNA variants (≤1% allele frequency) in breast cancer cell lines MDA-MB-231 and MCF-7 by single-molecule real-time (SMRT) sequencing, UltraSEEK chemistry based mass spectrometry, and digital PCR. …”
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    Sensitive detection of mitochondrial DNA variants for analysis of mitochondrial DNA-enriched extracts from frozen tumor tissue
  7. 88547
    “…METHODS: The impact of occupational exposure to submicrometer and UFPs was assessed in 30 healthy police shooting instructors by clinical investigation, self-assessment questionnaire, sputum and spirometry and compared to a control group. General laboratory chemistry parameters, circulating cytokines (interleukin [IL]-2, IL-4, IL-5, IL-6, IL-8, interferon-gamma [IFN-γ]), and granulocyte macrophage colony-stimulating factor (GM-CSF) in serum were measured. …”
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    Occupational exposure to ultrafine particles in police officers: no evidence for adverse respiratory effects
  8. 88548
    “…Organo-mineral associations, especially those with iron (Fe) oxides, drive the chemistry of OC sequestration and stability in soils. …”
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    The synergistic effect of calcium on organic carbon sequestration to ferrihydrite
  9. 88549
    “…The geographical variation in water chemistry, which has set the scene for – and interacted with – anthropogenic impact, is much less well understood. …”
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    The Dangers of Being a Small, Oligotrophic and Light Demanding Freshwater Plant across a Spatial and Historical Eutrophication Gradient in Southern Scandinavia
  10. 88550
    “…The ability of the heterogenic MSC infusion to ameliorate liver fibrosis in mice was evaluated by a blood plasma chemistry index, pathological examination and liver fibrosis-associated gene expression. …”
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    Heterogenic transplantation of bone marrow-derived rhesus macaque mesenchymal stem cells ameliorates liver fibrosis induced by carbon tetrachloride in mouse
  11. 88551
    por Khan, Afaque H, Zaidi, Samina
    Publicado 2017
    “…We monitored complete blood chemistry (CBC) including the absolute neutrophil count on a weekly basis. …”
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    Clozapine: Improvement of Negative Symptoms of Schizophrenia
  12. 88552
    “…A large array of techniques, including wet chemistry analysis, porosity measurements using NMR spectroscopy, electron and fluorescence microscopy, were used in order to determine possible generic factors of biomass recalcitrance. …”
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    Multimodal analysis of pretreated biomass species highlights generic markers of lignocellulose recalcitrance
  13. 88553
    “…Considering the interplay between behavior, morphology, and cuticular chemistry, specialists but not generalists have cracked the ants’ social code with respect to various sensory modalities. …”
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    Chemical and behavioral integration of army ant-associated rove beetles – a comparison between specialists and generalists
  14. 88554
    “…Assessment of sugar release as a result of dilute acid or dilute alkaline pretreatment and subsequent enzymatic hydrolysis suggested that when anaerobic conditions were maintained in storage, sugar release was either similar to or greater than as-harvested material depending on the pretreatment chemistry used. This study demonstrates that wet logistics systems offer practical benefits for commercial corn stover supply, including particle size reduction during harvest, stability in storage, and compatibility with biochemical conversion of carbohydrates for biofuel production. …”
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    Compatibility of High-Moisture Storage for Biochemical Conversion of Corn Stover: Storage Performance at Laboratory and Field Scales
  15. 88555
    “…All patients were studied by CBC and routine chemistry, as well as hs CRP, Intact PTH, lipid profile and endotoxin level by ELISA before and after the HD session, Delta change of endotoxin (pre dialysis endotoxin-post dialysis endotoxin) was calculated, resting Doppler echocardiographic and carotid duplex. …”
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    Cardiovascular risk of circulating endotoxin level in prevalent hemodialysis patients
  16. 88556
    “…The structures of these activated compounds are well described by quantum chemistry calculations, which have allowed us to determine their mechanical properties, as well as identify their soft deformation modes and a large number of low-energy vibration modes. …”
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    Polycatenated 2D Hydrogen-Bonded Binary Supramolecular Organic Frameworks (SOFs) with Enhanced Gas Adsorption and Selectivity
  17. 88557
    “…Safety was assessed by adverse events, chemistry panels, ECGs and physical examinations. RESULTS: Serum pharmacodynamic data demonstrated the maximum percent decrease in serum urate (sUA) from baseline (E(max)) at 8–12 hours after dosing. …”
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    Pharmacodynamic and pharmacokinetic effects and safety of verinurad in combination with febuxostat in adults with gout: a phase IIa, open-label study
  18. 88558
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    Synthesis and in vitro biochemical evaluation of oxime bond-linked daunorubicin–GnRH-III conjugates developed for targeted drug delivery
  19. 88559
    “…This hinders QDs applicability in living systems. Surface chemistry has a profound impact on biological behavior of QDs. …”
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    Improving cytocompatibility of CdTe quantum dots by Schiff-base-coordinated lanthanides surface doping
  20. 88560
    “…However, compared with triptolide-treated WT mice, no significant differences in either blood chemistry or histopathology were recorded. Furthermore, pharmacokinetic studies showed no significant differences between triptolide-treated Xh-CL and WT mice. …”
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    Extrahepatic cytochrome P450s play an insignificant role in triptolide-induced toxicity
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