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  1. 88561
    “…Fasting venous blood at baseline and 8 weekly intervals was used for blood chemistry. RESULTS: After 24 weeks, M(S) and F(S) with total cholesterol (TC) of >5.2 mmol/L and >5.3 mmol/L decreased from 22.2% to 14.8% and from 30.9% to 11.5%, respectively. …”
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    Effect of short and long moderate-intensity exercises in modifying cardiometabolic markers in sedentary Kenyans aged 50 years and above
  2. 88562
    por Choi, Insook
    Publicado 2018
    “…Case studies are implemented with two computational models, Chua's circuit and Swarm Chemistry social agent simulation, generating data in real-time that exhibits emergent behavior. …”
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    Interactive Sonification Exploring Emergent Behavior Applying Models for Biological Information and Listening
  3. 88563
    “…Using a mouse model of controlled cortical impact (CCI) we tested if (1) brain tissue levels of SCOP/PHLPP1 increase after a traumatic brain injury (TBI), and (2) if SCOP/PHLPP1 gene knockout (KO) mice have improved (or worse) neurologic outcomes. Blood chemistry (pH, pCO(2), pO(2), pSO(2), base excess, sodium bicarbonate, and osmolarity) and arterial pressure (MAP) differed in isoflurane anesthetized WT vs. …”
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    Acute Physiology and Neurologic Outcomes after Brain Injury in SCOP/PHLPP1 KO Mice
  4. 88564
    “…Body weight and glucose tolerance tests were conducted several times during the course of the study. Serum chemistry, liver enzymes, and biomarkers of bone metabolism were evaluated at 10 and 28 weeks. …”
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    Metabolic Syndrome and Bone: Pharmacologically Induced Diabetes has Deleterious Effect on Bone in Growing Obese Rats
  5. 88565
    “…DOC can also affect reactivity of heavy metals, water and sediment chemistry. This indirectly affects macrophytes too, so they are exposed to multiple stressors that may have contradictive effects. …”
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    The Future of Freshwater Macrophytes in a Changing World: Dissolved Organic Carbon Quantity and Quality and Its Interactions With Macrophytes
  6. 88566
    “…BACKGROUND: Sepsis is now operationally defined as life-threatening organ dysfunction caused by an infection, identified by an acute change in SOFA-Score of at least two points, including clinical chemistry such as creatinine or bilirubin concentrations. …”
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    Increased circulating microRNA-122 is a biomarker for discrimination and risk stratification in patients defined by sepsis-3 criteria
  7. 88567
    “…Chemical analyzes have been conducted at the Faculty of Chemistry, Ss. Cyril and Methodius University in Skopje. …”
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    The Effect of Ca and Mg Concentrations and Quantity and Their Correlation with Caries Intensity in School-Age Children
  8. 88568
    “…The bioassay has identified compound 2 (Specs ID: AN-979/41971160) as a HDAC3I (IC(50) = 6.1 μM), which proved the efficacy of our workflow. As a medicinal chemistry study, we performed a follow-up substructure search and identified two more hit compounds of the same chemical type, i.e. 2–1 (AQ-390/42122119, IC(50) = 1.3 μM) and 2–2 (AN-329/43450111, IC(50) = 12.5 μM). …”
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    The discovery of novel HDAC3 inhibitors via virtual screening and in vitro bioassay
  9. 88569
    “…In the second reaction using copper-free click chemistry, the azide-functionalized rGAA was conjugated with dibenzocyclooctyne-functionalized M6PgPs without the loss of enzyme activity. …”
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    Lysosomal Targeting Enhancement by Conjugation of Glycopeptides Containing Mannose-6-phosphate Glycans Derived from Glyco-engineered Yeast
  10. 88570
    “…No matter the source, increasing nitrogen in the boreal forest ecosystem will influence the resource situation for its primary producers, the plants, with possible implications for their defensive chemistry. In general, fertilization reduces phenolic compound concentrations in trees, but existing evidence mainly comes from studies on young plants. …”
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    Fertilization Changes Chemical Defense in Needles of Mature Norway Spruce (Picea abies)
  11. 88571
    “…Interestingly, both tests were demonstrated to be highly comparable, irrespective of differences in amplification chemistry or sequences targeted. Host differences, incidence of disease and geographical location of the isolates had little impact on the positivity recorded by each of the diagnostic methods. …”
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    A new TaqMan method for the reliable diagnosis of Ehrlichia spp. in canine whole blood
  12. 88572
    “…Aided by the universality of the laws of physics and chemistry, we turn to Earth's biosphere, both in the present and through geologic time, for analog signatures that will aid in the search for life elsewhere. …”
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    Exoplanet Biosignatures: A Review of Remotely Detectable Signs of Life
  13. 88573
    “…Using metabolic labeling-coupled click chemistry method, the functionality of this recombinant enzyme could be authenticated in E. coli strain expressing LdPAT4-DHHC domain. …”
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    Identification and Characterization of a Novel Palmitoyl Acyltransferase as a Druggable Rheostat of Dynamic Palmitoylome in L. donovani
  14. 88574
    “…The relatively straightforward radiosynthesis and efficient CXCR4 targeting of [(18)F]AlF-NOTA-pentixather demonstrate the successful implementation of (18)F-complexation chemistry and pentixather-based CXCR4 targeting. Upon pharmacokinetic optimization, this class of tracers holds great promise for future application in humans.…”
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    First (18)F-Labeled Pentixafor-Based Imaging Agent for PET Imaging of CXCR4 Expression In Vivo
  15. 88575
    “…This view represents a major shift in our understanding of the evolution of marine chemistry. However, thus far, evidence for ferruginous conditions comes predominantly from Fe-speciation data. …”
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    Earth’s youngest banded iron formation implies ferruginous conditions in the Early Cambrian ocean
  16. 88576
    “…We found that changes in water chemistry and dissolved organic matter quality brought about by agricultural inputs were clearly expressed in the δ(15)N signatures of animal tissues from all trophic levels. …”
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    Tracing anthropogenic inputs in stream foods webs with stable carbon and nitrogen isotope systematics along an agricultural gradient
  17. 88577
    “…From admission to recovery, hematology and plasma chemistry data improved as expected. The most informative prognostic indicators, as determined by correlations with a novel severity indicator (based on survival times), were plastron concavity, P, albumin, total solids, UA, lymphocyte proliferation, WBC, K, Glc, Ca:P, and PCV. …”
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    Chronic debilitation in stranded loggerhead sea turtles (Caretta caretta) in the southeastern United States: Morphometrics and clinicopathological findings
  18. 88578
    “…[Image: see text] Characterization of slow chemical reactions is essential for assessing catalytic efficiency in chemistry and biology. Traditionally, chemical reaction rates are obtained from population relaxation kinetics measurements and the Arrhenius equation. …”
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    Characterizing Slow Photochemical Reaction Kinetics by Enhanced Sampling of Rare Events with Capillary Optical Fibers and Kramers’ Theory
  19. 88579
    “…METHODS: We used the Geochemical Baseline Survey of the Environment (G-BASE), a systematic X-ray fluorescence survey of soil inorganic chemistry throughout England and Wales to obtain estimates of the concentrations of 15 elements in the soil contained within each English and Welsh postcode area. …”
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    Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health
  20. 88580
    “…Pre-dose and post-dose safety assessments included physical examinations (including neurological examination); orthostatic vital signs; 6-lead continuous electrocardiogram (ECG) telemetry monitoring pre-dose to 8 h post-dose; 12-lead ECGs; clinical chemistry, hematology, and urinalysis; mini mental status examinations; and adverse events. …”
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    A Double-Blind, Placebo-Controlled Trial Demonstrating the Safety, Tolerability, and Pharmacokinetics of Single, Escalating Oral Doses of RTI-336
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