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  1. 88601
    “…In order both to trace the success of these nanoplatforms on the release of the bioactive cargo in the CNS and determinate the concentration at trace levels of targets biomolecules by analytical chemistry and concretely separation instrumental techniques, constitute an essential tool. …”
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    Neuroprotective Natural Molecules, From Food to Brain
  2. 88602
    “…Overall, these results demonstrate that the use of a structure-wide QM/MM Hamiltonian exhibits improvements in the local structural chemistry of the ligand similar to Region-QM refinement but with significant improvements in the overall structure beyond the active site.…”
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    High-throughput quantum-mechanics/molecular-mechanics (ONIOM) macromolecular crystallographic refinement with PHENIX/DivCon: the impact of mixed Hamiltonian methods on ligand and protein structure
  3. 88603
    “…METHODS: In this study we investigated the distribution of distractor efficacy in exams from four large first-year undergraduate courses in chemistry and in anatomy and physiology in a Health Faculty; assessed the impact on overall student score after changing from five-option to four-option single best answer multiple choice questions; and assessed the impact of changing from five options to four options on item difficulty and discrimination. …”
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    Analysis of MCQ and distractor use in a large first year Health Faculty Foundation Program: assessing the effects of changing from five to four options
  4. 88604
    “…At 32–33 d of age, blood was collected for serum chemistry and blood cellular analyses, and coagulation time. …”
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    Evaluation of Sialyllactose Supplementation of a Prebiotic-Containing Formula on Growth, Intestinal Development, and Bacterial Colonization in the Neonatal Piglet
  5. 88605
    “…The finding of considerable amino acids and alkyl amines in continental and marine aerosols may exert significant implications on nitrogen cycling and atmospheric chemistry.…”
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    Development and validation of a HPLC/FLD method combined with online derivatization for the simple and simultaneous determination of trace amino acids and alkyl amines in continental and marine aerosols
  6. 88606
    “…Blood testing was performed either with POC instruments for blood gases and chemistry panel, full blood count, and CRP, or at central laboratory, or as a combination of both. …”
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    Comparison of the use of comprehensive point-of-care test panel to conventional laboratory process in emergency department
  7. 88607
    “…METHODS: Adults from whom the treating physician planned to take blood cultures and additional blood chemistry tests, in the same venous puncture, were eligible and were randomly assigned to intervention or control arms. …”
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    1148. Reduction of Blood Culture Contamination Rates by an Altered Sampling Protocol: Single-Center, Prospective, Randomized, Controlled, Open-Label Trial
  8. 88608
    “…Body composition (DEXA), muscular strength, power, and endurance, 7.5 km cycling time trial, and clinical blood chemistries were measured at baseline and after 12 weeks of supplementation and training. …”
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    Effects of an Aqueous Extract of Withania somnifera on Strength Training Adaptations and Recovery: The STAR Trial
  9. 88609
    “…Forty male C57BL/6J mice were fed a normal diet (ND, n = 10), high-fat diet (HFD, 60% fat, w/w, n = 10), HFD supplemented with 200 mg/kg of SGE or garcinia (GAR) by weight (SGED or GARD, respectively, n = 10) for 12 weeks. Serum chemistry was examined, and the expressions of genes involved in lipid metabolism were determined in the liver. …”
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    The antioxidant activity of steamed ginger and its protective effects on obesity induced by high-fat diet in C57BL/6J mice
  10. 88610
    “…However, the deep microbial community is still largely unknown and can be influenced by parameters such as temperature, pressure, water residence times, and chemistry of the waters. In this study, 21 boreholes representing a range of deep continental groundwaters from the Äspö Hard Rock Laboratory were subjected to high-throughput 16S rRNA gene sequencing to characterize how the different water types influence the microbial communities. …”
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    Depth and Dissolved Organic Carbon Shape Microbial Communities in Surface Influenced but Not Ancient Saline Terrestrial Aquifers
  11. 88611
    “…In terms of individual mol­ecules, O⋯H/H⋯O contacts are more important for the TDBA (ca 28%) than for the TPPO mol­ecules (ca 13%), as expected from the chemical composition of these species. Computational chemistry indicates the four independent hy­droxy-O—H⋯O(oxide) hydrogen bonds in the crystal impart about the same energy (ca 52 kJ mol(−1)), with DTBA-phenyl-C—H⋯O(oxide) inter­actions being next most stabilizing (ca 40 kJ mol(−1)).…”
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    A 1:2 co-crystal of 2,2′-thiodi­benzoic acid and tri­phenyl­phosphane oxide: crystal structure, Hirshfeld surface analysis and computational study
  12. 88612
    “…At the age of 4 months, the animals were euthanized; trabecular and cortical bone samples from the femur, the tibia, the humerus, and the fourth vertebral body harvested during necropsy were assessed by microcomputed tomography and dynamic histomorphometry. In addition, blood chemistry and blood alcohol determinations were performed. …”
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    Bone Effects of Binge Alcohol Drinking Using Prepubescent Pigs as a Model
  13. 88613
    “…To our knowledge, this represents the first reported systematic analysis of how pretargeted imaging is affected solely by variation in click reaction stoichiometry through site-specific conjugation chemistry.…”
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    Site-specific conjugation allows modulation of click reaction stoichiometry for pretargeted SPECT imaging
  14. 88614
    “…Also, the characterization of a parasiticidal metabolite facilitates an understanding and improvement of the chemistry, and identification of the mechanism of action and/or target.…”
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    TPT sulfonate, a single, oral dose schistosomicidal prodrug: In vivo efficacy, disposition and metabolic profiling
  15. 88615
    “…Using computational and medicinal chemistry-assisted approaches, we established novel NGLY1-inhibitory small molecules. …”
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    Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1
  16. 88616
    “…All patients underwent a clinical evaluation, routine chemistry, an echocardiogram and a renal echo-Doppler. …”
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    Renal Venous Pattern: A New Parameter for Predicting Prognosis in Heart Failure Outpatients
  17. 88617
    “…The core tools of the SMART program are resources and relationships: university-designed or commercial water data collection equipment, data loggers and chemistry supplies, on-campus science and engineering training for teacher-mentors and students, and a community mentor network. …”
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    Changing the face of STEM with stormwater research
  18. 88618
    “…The membranes possess a fully interconnected network of poly(acrylic acid)-lined pores, which enables the surface chemistry to be tailored through sequential attachment of polyethylenimine brushes and metal-binding terpyridine ligands. …”
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    High-Affinity Detection and Capture of Heavy Metal Contaminants using Block Polymer Composite Membranes
  19. 88619
    “…Target sequence enrichment (48.48 Fluidigm Access Arrays) and sequencing were performed (Illumina Hi‐Seq 2,500 instrument, v4 chemistry). Differences in patient and tumor characteristics of BRCA1/2 carriers who were already identified as part of clinical BRCA1/2 testing routines and additional BRCA1/2 carriers found by sequencing the entire study population were compared using logistic regression models. …”
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    Prevalence of BRCA1 and BRCA2 pathogenic variants in a large, unselected breast cancer cohort
  20. 88620
    “…How changes in the mouse glycoproteins’ chemistry affect phenotype and function of transplanted human hematopoietic stem cells and mature human immune cells in the course of HIV-1 infection are not known. …”
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    Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection
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