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89061por Yoon, Hyung-Suk, Shu, Xiao-Ou, Shidal, Chris, Wu, Jie, Blot, William J., Zheng, Wei, Cai, Qiuyin“…Serum levels of total bilirubin and albumin, collected up to 11 years prior to case diagnoses, were measured by a clinical chemistry analyzer. Conditional logistic regression models were applied to evaluate the associations of total bilirubin and albumin with lung cancer risk. …”
Publicado 2022
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89062por da Costa, Renato A., da Rocha, João A. P., Pinheiro, Alan S., da Costa, Andréia do S. S., da Rocha, Elaine C. M., Silva, Rai. C., Gonçalves, Arlan da S., Santos, Cleydson B. R., Brasil, Davi do S. B.“…Physicochemical properties, lipophilicity, water solubility, pharmacokinetics, druglikeness and medicinal chemistry were evaluated for four compounds that were more promising, showed negative indices for the potential penetration of the Blood Brain Barrier and expressed high human intestinal absorption, indicating a low risk of central nervous system depression or drowsiness as the the side effects. …”
Publicado 2022
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89063por Habib, Amina, Lo, Stéphane, Villageois-Tran, Khanh, Petitjean, Marie, Malik, Shaheen Akhtar, Armand-Lefèvre, Laurence, Ruppé, Etienne, Zahra, Rabaab“…Identification was performed by using conventional biochemical tests, and genomes were sequenced using Illumina chemistry. Antibiotic resistance genes, plasmid incompatibility groups, and Escherichia coli phylogroups were determined in silico. …”
Publicado 2022
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89064por Oliveira, Fernanda A., Pinto, Ana Claudia S., Duarte, Caique L., Taranto, Alex G., Lorenzato Junior, Eder, Cordeiro, Cleydson Finotti, Carvalho, Diogo T., Varotti, Fernando P., Fonseca, Amanda L.“…N-acylhydrazones are considered privileged structures in medicinal chemistry, being part of antimicrobial compounds (for example). …”
Publicado 2022
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89065“…This review critically reflects upon the fundamental aspects of resin embedding with regard to 1) specimen fixation and the physics and chemistry underlying the preservation of protein structure with respect to fluorescence and antigenicity, 2) optimization of EM contrast for transmission or scanning EM, and 3) the choice of embedding resin. …”
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89066por Mohr, Amanda L A, Logan, Barry K, Fogarty, Melissa F, Krotulski, Alex J, Papsun, Donna M, Kacinko, Sherri L, Huestis, Marilyn A, Ropero-Miller, Jeri D“…The primary objective of this study is to assist in the assessment and interpretation of these cases as well as provide references for confirmation methods. Chemistry, pharmacology, adverse events and user profiles (e.g., polypharmacy) for NPS are provided including case history, clinical symptoms, autopsy findings and analytical results. …”
Publicado 2022
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89067por Choi, Jinkyul, Henze, Daven K., Cao, Hansen, Nowlan, Caroline R., González Abad, Gonzalo, Kwon, Hyeong‐Ahn, Lee, Hyung‐Min, Oak, Yujin J., Park, Rokjin J., Bates, Kelvin H., Maasakkers, Joannes D., Wisthaler, Armin, Weinheimer, Andrew J.“…We first update a three‐dimensional (3D) chemical transport model, GEOS‐Chem with the KORUSv5 anthropogenic emission inventory and inclusion of chemistry for aromatics and C(2)H(4), leading to modest improvements in simulation of CH(2)O (normalized mean bias (NMB): −0.57 to −0.51) and O(3) (NMB: −0.25 to −0.19) compared against DC‐8 aircraft measurements during KORUS‐AQ; the mixing ratio of most VOC species are still underestimated. …”
Publicado 2022
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89068por Weiser, John, Tie, Yunfeng, Lu, Jen-Feng, Colasanti, Jonathan A, Fanfair, Robyn Neblett, Beer, Linda“…RESULTS: Within 6 months of care initiation, HIV monitoring tests were performed for 91.3% (95% CI, 88.7%–93.8%) of patients; coinfection blood tests, 27.5% (95% CI, 22.5%–32.4%); site-based STI tests, 59.7% (95% CI, 55.4%–63.9%); and blood chemistry and hematology tests, 50.8% (95% CI, 45.8%–55.8%). …”
Publicado 2022
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89069por Wilmeth, Dylan T., Myers, Kimberly D., Lalonde, Stefan V., Mänd, Kaarel, Konhauser, Kurt O., Grandin, Prisca, van Zuilen, Mark A.“…Floating mats in El Tatio therefore represent a specific sinter preservation window, where evaporation in silica‐undersaturated microbial mats produces crusts, which preserve cells and affect mat chemistry, but low‐silica concentrations prevent the formation of lasting sinter deposits. …”
Publicado 2021
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89070por Huerta-Flores, Ali Margot, Ruiz-Zepeda, Francisco, Eyovge, Cavit, Winczewski, Jedrzej P., Vandichel, Matthias, Gaberšček, Miran, Boscher, Nicolas D., Gardeniers, Han J.G.E., Torres-Martínez, Leticia M., Susarrey-Arce, Arturo“…This work synthesized a new type of Ta(2)O(5)/SrZrO(3) heterostructure with Ru and Cu (RuO(2)/Cu(x)O/Ta(2)O(5)/SrZrO(3)) using solid-state chemistry methods to achieve a high H(2) production of 5164 μmol g(–1) h(–1) under simulated solar light, 39 times higher than that produced using SrZrO(3). …”
Publicado 2022
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89071por Edgworth, Eileen, Ernst, Lisa, Czigany, Zoltan, Saritas, Turgay, Zarnitz, Laura Sophie, Wiartalla, Marc, Boor, Peter, Buhl, Eva Miriam, Rossaint, Rolf, Tolba, René H., Doorschodt, Benedict, Fabry, Gregor, Bleilevens, Christian“…Kidneys in the HBOC groups had a significantly lower renal blood flow and increasing intrarenal resistance, with reduced renal function in comparison to the pRBC groups, as demonstrated by significantly lower creatinine clearance and higher fractional sodium excretion rates. Clinical chemistry markers for tissue damage (LDH, lactate) were higher in the HBOC groups, whereas no significant histological differences were observed. …”
Publicado 2022
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89072por Montero, Vincent, Montana, Marc, Khoumeri, Omar, Correard, Florian, Estève, Marie-Anne, Vanelle, Patrice“…The quinoxaline core is a promising scaffold in medicinal chemistry. Multiple quinoxaline derivatives, such as the topoisomerase IIβ inhibitor XK-469 and the tissue transglutaminase 2 inhibitor GK-13, have been evaluated for their antiproliferative activity. …”
Publicado 2022
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89073por Dai, Shunhong, Georgelis, Nikolaos, Bedair, Mohamed, Hong, Yun‐Jeong, Qi, Qungang, Larue, Clayton T, Sitoula, Bikram, Huang, Wei, Krebel, Brian, Shepard, Michael, Su, Wen, Kretzmer, Keith, Dong, Jiaxin, Slewinski, Thomas, Berger, Sarah, Ellis, Christine, Jerga, Agoston, Varagona, Marguerite“…The TDO‐mediated soybean mesotrione tolerance trait described here provides farmers with a new option to effectively manage difficult‐to‐control weeds using familiar herbicide chemistry. This trait can also be adapted to other mesotrione‐sensitive crops (e.g. cotton) for effective weed management. © 2022 Bayer Crop Science. …”
Publicado 2022
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89074“…There were substantial differences between species, but both methods suggested nonmixing populations at the regional scale. Otolith chemistry can be an effective tool in discriminating variation for deepwater marine species in multispecies fisheries, and edge measurements from LA‐ICP‐MS provided the greatest resolution. …”
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89075por Meng, Zijuan, Xue, Huiying, Wang, Tingting, Chen, Biao, Dong, Xiyuan, Yang, Lili, Dai, Jun, Lou, Xiaoding, Xia, Fan“…This review hopes to stimulate the interest of researchers in different fields such as chemistry, materials science, biology, and medicine, and promote the clinical translation of AIE-PSs. …”
Publicado 2022
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89076por Li, Guoli, Yin, Wei, Yang, Yiya, Yang, Hongyu, Chen, Yinyin, Liang, Yumei, Zhang, Weiru, Xie, Tingting“…The journals with the highest output and the highest co-citation frequency were Autophagy (N = 208) and Journal of Biological Chemistry (co-citation: 17226), respectively. Analyses of references and keywords suggested that “mechanism of mitochondrial quality control”, “molecule and signaling pathway in mitophagy”, and “mitophagy related diseases” were research hotspots, and parkin-mediated mitophagy and its roles in skeletal muscle and inflammation-related diseases may be the frontiers of future research. …”
Publicado 2022
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89077“…INTRODUCTION: As biological activity components, α-aminophosphonates and their moieties play important roles in medicinal chemistry. Alpha-phosphonic acids are significant α-amino acid counterparts. …”
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89078“…The physical properties, chemical structure, surface chemistry properties of Cu-BC and Zn-BC were characterized by Zeta potential meter, Scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDX), Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). …”
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89079por Hao, Dake, Lu, Lu, Song, Hengyue, Duan, Yixin, Chen, Jianing, Carney, Randy, Li, Jian Jian, Zhou, Ping, Nolta, Jan, Lam, Kit S., Leach, J. Kent, Farmer, Diana L, Panitch, Alyssa, Wang, Aijun“…Methods: SILY was conjugated to the surface of mesenchymal stem/stromal cell (MSC)-derived EVs by using click chemistry to construct SILY-EVs. Nanoparticle tracking analysis (NTA), ExoView analysis, cryogenic electron microscopy (cryo-EM) and western-blot analysis were used to characterize the SILY-EVs. …”
Publicado 2022
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89080“…These systems demonstrate spatial control of cell interaction through simple changes in monomer chemistry. Fine control over chemical presentation during the fabrication of biomaterial implants could lead to greater efficacy and targeted regeneration of semi-complex tissues.…”
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