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  1. 89861
    “…Tumor samples from 50 women with early breast cancer were genotyped using the iPlex(®)Gold chemistry and MassARRAY platform, and patients were classified as good responders (Miller–Payne tumor grades 4–5) and poor responders (Miller–Payne tumor grades 1–3), as assessed upon surgery after 6 months of treatment. …”
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    HER2 and BARD1 Polymorphisms in Early HER2-Positive Breast Cancer Patients: Relationship with Response to Neoadjuvant Anti-HER2 Treatment
  2. 89862
    “…Liver and serum were collected for pathology and clinical chemistry, respectively. RNA-sequencing coupled with pathway analysis was used to determine molecular mechanisms. …”
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    Identifying Human Specific Adverse Outcome Pathways of Per- and Polyfluoroalkyl Substances Using Liver-Chimeric Humanized Mice
  3. 89863
    “…In this study, a green chemistry method was used to synthesize polymer composites based on polyethylene oxide (PEO). …”
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    Variation in the Optical Properties of PEO-Based Composites via a Green Metal Complex: Macroscopic Measurements to Explain Microscopic Quantum Transport from the Valence Band to the Conduction Band
  4. 89864
    “…METHODS: A systematic search of the PubMed, Embase, and Cochrane Library databases from inception to August 12, 2022, was performed to analyse the reported liver chemistry data for patients diagnosed with COVID-19. …”
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    Liver injury associated with the severity of COVID-19: A meta-analysis
  5. 89865
    “…Understanding how extended excess soil moisture exacerbated by extreme weather events affects changes in iron (Fe) chemistry is crucial for assessing environmental risk associated with soil phosphorus (P) in high P soils. …”
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    Solubility of soil phosphorus in extended waterlogged conditions: An incubation study
  6. 89866
    “…Deeper insights into the structure–activity landscape highlighted a total of seven significant activity cliff (AC) generators (ChEMBL molecule IDs: 160257, 418198, 4082265, 348918, 390728, 4080698, and 6530), which provide valuable SAR information for medicinal chemistry. The findings in this study provide new insights and guidelines for hit identification and lead optimization for the development of novel AR antagonists.…”
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    Cheminformatic Analysis and Machine Learning Modeling to Investigate Androgen Receptor Antagonists to Combat Prostate Cancer
  7. 89867
    “…Trends in the thermodynamic stability of the new compounds are explained on the basis of crystal-chemistry and density functional theory (DFT). Further DFT calculations examine the relative stability of the CF versus spinel structures at various degrees of sodium extraction in the context of electrochemical battery reactions.…”
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    Expanding the Ambient-Pressure Phase Space of CaFe(2)O(4)-Type Sodium Postspinel Host–Guest Compounds
  8. 89868
    “…Although the field of MV chemistry is matured, there remain issues to be solved, which cannot be accessed by the conventional analytical methods. …”
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    Estimation of Electron Distribution over Dinuclear Organometallic Molecular Wires by “IR Tag” Analysis of Ancillary Acyl-Cp Ligands
  9. 89869
    “…Polyethylene glycol (PEG) chains were incorporated via conventional conjugation methods or a click chemistry reaction forming a 1,4-disubstituted 1,2,3-triazole (Trz) linkage for the optimization of in vivo kinetics as necessary. …”
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    A Theranostic Small-Molecule Prodrug Conjugate for Neuroendocrine Prostate Cancer
  10. 89870
    “…In recent years, selective COX-2 inhibitors with a lower incidence of adverse effects attained an important position in medicinal chemistry. In order to introduce some new potent COX-2 inhibitors, a new series of 2-(4-(methylsulfonyl)phenyl)-N-phenylimidazo[1,2-a]pyridin-3-amines was designed, synthesized, and evaluated. …”
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    Design, synthesis, and biological evaluation of new 2-(4-(methylsulfonyl)phenyl)-N-phenylimidazo[1,2-a]pyridin-3-amine as selective COX-2 inhibitors
  11. 89871
    “…No consistent or clinically relevant treatment‐related changes from baseline were observed for hematology, clinical chemistry parameters, vital signs, or 12‐lead electrocardiograms. …”
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    Safety and tolerability of short‐term infusions of intravenous lacosamide in pediatric patients with epilepsy: An open‐label, phase 2/3 trial
  12. 89872
    “…METHODS: We quantitatively measured creatine kinase (CK) using the International Federation of Clinical Chemistry reference method, creatine/creatinine(ratio) (Cr/Crn) using liquid chromatography–tandem mass spectrometry, and myostatin with ELISA in serum and assessed functional performance using the North Star Ambulatory Assessment (NSAA), 10-meter run velocity (TMRv), 6-Minute Walking Test (6MWT), and forced vital capacity in a 4-year prospective natural history study. …”
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    Longitudinal Assessment of Creatine Kinase, Creatine/Creatinine(ratio), and Myostatin as Monitoring Biomarkers in Becker Muscular Dystrophy
  13. 89873
    por Khalilia, Walid M.
    Publicado 2023
    “…Therefore, FS is an extremely interdisciplinary field at the interface of chemistry, biology, physics, medicine, law, criminology, and other related sciences. …”
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    Curriculum of bachelor’s degree in forensic science at Al Istiqlal University in Palestine and students’ evaluation of the model
  14. 89874
    “…It is concluded that the areas that produce the most scientific documents at the UAQ are engineering, technology, chemistry and physics, signed in coauthorship in national and international networking.…”
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    The scientific production of the Autonomous University of Querétaro indexed in WOS, 2010-2020
  15. 89875
    “…Applying the green analytical chemistry methods to assess the proposed methods has widely attained the analytical community care. …”
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    Three developed spectrophotometric methods for determination of a mixture of ofloxacin and ornidazole; application of greenness assessment tools
  16. 89876
    “…After obtaining informed consent, about 5 ml of venous blood was collected to perform lipid profile using DIRUI CS-T240 automated clinical chemistry analyzer. Independent t-test, Mann–Whitney U test, Kruskal-Wallis H test, correlation tests, and logistic regression were used during data analysis. …”
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    Serum lipid profile of stroke patients attending at Dessie comprehensive specialized hospital, Dessie, Northeast Ethiopia: A comparative cross-sectional study
  17. 89877
    “…These observations indicated that bromine chemistry enhances the formation of OClO, which is subsequently oxidized into HClO(3) and HClO(4) by hydroxyl radicals. …”
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    Widespread detection of chlorine oxyacids in the Arctic atmosphere
  18. 89878
    “…Results The FBS levels among T2DM patients (211.6 ± 60.97 mg/dL) and non-diabetic individuals (87.34 ± 13.06 mg/dL) were significantly (p < 0001) different. Analysis of lipid chemistry that included TC (174.8 ± 38.28 mg/dL vs. 157.22 ± 30.34 mg/dL), TAG (173.14 ± 83.48 mg/dL vs. 133.94 ± 39.69 mg/dL), HDL-C (37.28 ± 7.84 mg/dL vs. 43.4 ± 10.82 mg/dL), LDL-C (113.44 ± 28.79 mg/dL vs. 96.72 ± 21.53 mg/dL), and VLDL-C (34.58 ± 19.02 mg/dL vs. 26.7 ± 8.61 mg/dL) revealed significant variations among T2DM and non-diabetic individuals. …”
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    Dyslipidemia Among Diabetes Mellitus Patients: A Case-Control Study From a Tertiary Care Hospital in South India
  19. 89879
    por Pasquini, Marta, Stenta, Marco
    Publicado 2023
    “…On the one side, Computer-Aided Synthesis Planning tools can predict synthetic routes in a model-driven approach; on the other side, experimental routes can be extracted from the Network of Organic Chemistry, in which reaction data are linked in a network. …”
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    LinChemIn: SynGraph—a data model and a toolkit to analyze and compare synthetic routes
  20. 89880
    “…Generalizing this approach, we designed a so-called “click cage” that can be coupled to lipids and offers the possibility to attach organelle targeting groups via click chemistry. Using this strategy, we have synthesized plasma membrane, lysosomal, mitochondria, and endoplasmic-reticulum-targeted lipids that can be used to dissect organelle-specific signaling events. …”
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    The Road to Quantitative Lipid Biochemistry in Living Cells
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