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  1. 89921
    “…Male Swiss albino mice (n = 49) were randomly assigned to seven groups: control, dietary Chia, CoQ(10), IOL, IOL + Chia, IOL + CoQ(10), and IOL + Chia + CoQ(10). Computational chemistry indicates that the phytic acid found in the Chia seeds is stable, reactive, and able to bind to up to three iron ions (both Fe(2+) and Fe(3+)). …”
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    Chia seeds and coenzyme Q(10) alleviate iron overload induced hepatorenal toxicity in mice via iron chelation and oxidative stress modulation
  2. 89922
    “…The drug-likeness and ADMET studies of all the benzofuran-1,2,4-triazole derivatives BF8–BF15 revealed that these compounds possessed good medicinal chemistry profiles in agreement with all the evaluated parameters for being drugs. …”
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    An Exploration of the Inhibitory Mechanism of Rationally Screened Benzofuran-1,3,4-Oxadiazoles and-1,2,4-Triazoles as Inhibitors of NS5B RdRp Hepatitis C Virus through Pharmacoinformatic Approaches
  3. 89923
    por Okarvi, Subhani M.
    Publicado 2023
    “…Methods: DOTA-coupled AngII peptide was synthesized by conventional solid-phase peptide synthesis according to Fmoc/HATU chemistry. (68)Ga/(177)Lu labeled AngII peptide was evaluated for its binding with TNBC MDA-MB-231 and ER+ MCF7 cell lines. …”
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    Preparation, Radiolabeling with (68)Ga/(177)Lu and Preclinical Evaluation of Novel Angiotensin Peptide Analog: A New Class of Peptides for Breast Cancer Targeting
  4. 89924
    “…Oxidant-triggered, genome-wide transcriptional changes should be analyzed considering changes in oxidative stress-responsive physiological conditions and not correlating them directly to the chemistry and concentrations of the oxidative stress-inducing agent.…”
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    Comparison of gene expression signatures of diamide, H(2)O(2 )and menadione exposed Aspergillus nidulans cultures – linking genome-wide transcriptional changes to cellular physiology
  5. 89925
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    Flexible synthesis of poison-frog alkaloids of the 5,8-disubstituted indolizidine-class. II: Synthesis of (-)-209B, (-)-231C, (-)-233D, (-)-235B", (-)-221I, and an epimer of 193E and pharmacological effects at neuronal nicotinic acetylcholine receptors
  6. 89926
    “…BACKGROUND: Exon skipping oligonucleotides (ESOs) of 2'O-Methyl (2'OMe) and morpholino chemistry have been shown to restore dystrophin expression in muscle fibers from the mdx mouse, and are currently being tested in phase I clinical trials for Duchenne Muscular Dystrophy (DMD). …”
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    Nanopolymers improve delivery of exon skipping oligonucleotides and concomitant dystrophin expression in skeletal muscle of mdx mice
  7. 89927
    “…The HIV-1 pol gene was amplified using primers recognizing conserved viral sequences and sequenced employing BigDye chemistry from 100 HIV-1 seropositive treatment-naïve pregnant women and 61 HIV-1 seropositive women who had received a single dose of Nevirapine (sdNVP). …”
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    Prevalence of reverse transcriptase and protease mutations associated with antiretroviral drug resistance among drug-naïve HIV-1 infected pregnant women in Kagera and Kilimanjaro regions, Tanzania
  8. 89928
    por D'Onofrio, David J, An, Gary
    Publicado 2010
    “…Biological systems do not have an external source for a map of their stored information or for an operational instruction set; rather, they must contain an organizational template conserved within their intra-nuclear architecture that "manipulates" the laws of chemistry and physics into a highly robust instruction set. …”
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    A comparative approach for the investigation of biological information processing: An examination of the structure and function of computer hard drives and DNA
  9. 89929
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    PubChem3D: Conformer generation
  10. 89930
    “…In the past, several methods to prepare such structures have been developed – ranging from wet chemistry-based to physical-based methods such as self-organization or cluster growth. …”
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    Structure, morphology, and magnetic properties of Fe nanoparticles deposited onto single-crystalline surfaces
  11. 89931
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    The Effect of the CO(3)(2- )to Ca(2+ )Ion activity ratio on calcite precipitation kinetics and Sr(2+ )partitioning
  12. 89932
    “…No significant changes suggestive of toxicity in routine hematologies, serum chemistries, liver enzymes or PTT were noted in any of the treatment groups. …”
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    A randomized, double blind, placebo and active comparator controlled pilot study of UP446, a novel dual pathway inhibitor anti-inflammatory agent of botanical origin
  13. 89933
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    Second campaign of microclimate monitoring in the carcer tullianum: temporal and spatial correlation and gradients evidenced by multivariate analysis
  14. 89934
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    Method for simultaneous analysis of eight analogues of vitamin D using liquid chromatography tandem mass spectrometry
  15. 89935
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    Effects of multiple conformers per compound upon 3-D similarity search and bioassay data analysis
  16. 89936
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    Antioxidant activity and mechanism of Rhizoma Cimicifugae
  17. 89937
    “…Uric acid, glucose, triglycerides (TG), total cholesterol, urea, creatinine, gamma-GT, albumin and calcium and HDL-c were quantified in serum by the dry-chemistry method. LDL-c was estimated by the Friedewald equation and ultrasensitive C-reactive protein (CRP) by the immunochemiluminiscence method. …”
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    Dietary, anthropometric, and biochemical determinants of uric acid in free-living adults
  18. 89938
    “…RESULTS: Obtaining a high yield of sugar from recalcitrant biomass generally requires a high severity of pretreatment with aggressive chemistry, followed by extensive conditioning, and large doses of enzymes. …”
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    Saccharification of recalcitrant biomass and integration options for lignocellulosic sugars from Catchlight Energy’s sugar process (CLE Sugar)
  19. 89939
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    Potential of silver against human colon cancer: (synthesis, characterization and crystal structures of xylyl (Ortho, meta, &Para) linked bis-benzimidazolium salts and Ag(I)-NHC complexes: In vitro anticancer studies)
  20. 89940
    “…METHODS: In this survey-based study, we examine the nature of hepatic FGF21 activation in liver tissues and tissue sections from several mouse liver disease models and human patients, by quantitative PCR, immunohistochemistry, protein chemistry, and reporter and CHIP assays. The liver diseases include genetic and chemical-induced HCC, liver injury and regeneration, cirrhosis, and other types of liver diseases. …”
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    Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress
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