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  1. 89961
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    Autonomous assembly of synthetic oligonucleotides built from an expanded DNA alphabet. Total synthesis of a gene encoding kanamycin resistance
  2. 89962
    “…Similarly, no noticeable trend for Grade 3–4 laboratory abnormalities was seen and Grade 3–4 hematologic changes and liver chemistry elevations were uncommon (neutropenia, 2.5%; AST/ALT elevations, 1% (n=196)). …”
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    Safety profile of HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 analysis
  3. 89963
    “…Environmental Toxicology and Chemistry published byWiley Periodicals, Inc. on behalf of SETAC. …”
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    Acute sensitivity of white sturgeon (Acipenser transmontanus) and rainbow trout (Oncorhynchus mykiss) to copper, cadmium, or zinc in water-only laboratory exposures
  4. 89964
    “…Born in Berea, Ohio, Professor Mark Hans attended Yale University in New Haven, CT, and earned his Bachelor of Science Degree in Chemistry. Upon graduation, Dr. Hans received his DDS and Masters Degree of Science in Dentistry with specialty certification in Orthodontics at Case Western Reserve University. …”
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    An interview with Mark G. Hans
  5. 89965
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    Effects of RAMEA-complexed polyunsaturated fatty acids on the response of human dendritic cells to inflammatory signals
  6. 89966
    por Krallinger, Martin, Rabal, Obdulia, Leitner, Florian, Vazquez, Miguel, Salgado, David, Lu, Zhiyong, Leaman, Robert, Lu, Yanan, Ji, Donghong, Lowe, Daniel M, Sayle, Roger A, Batista-Navarro, Riza Theresa, Rak, Rafal, Huber, Torsten, Rocktäschel, Tim, Matos, Sérgio, Campos, David, Tang, Buzhou, Xu, Hua, Munkhdalai, Tsendsuren, Ryu, Keun Ho, Ramanan, SV, Nathan, Senthil, Žitnik, Slavko, Bajec, Marko, Weber, Lutz, Irmer, Matthias, Akhondi, Saber A, Kors, Jan A, Xu, Shuo, An, Xin, Sikdar, Utpal Kumar, Ekbal, Asif, Yoshioka, Masaharu, Dieb, Thaer M, Choi, Miji, Verspoor, Karin, Khabsa, Madian, Giles, C Lee, Liu, Hongfang, Ravikumar, Komandur Elayavilli, Lamurias, Andre, Couto, Francisco M, Dai, Hong-Jie, Tsai, Richard Tzong-Han, Ata, Caglar, Can, Tolga, Usié, Anabel, Alves, Rui, Segura-Bedmar, Isabel, Martínez, Paloma, Oyarzabal, Julen, Valencia, Alfonso
    Publicado 2015
    “…We present the CHEMDNER corpus, a collection of 10,000 PubMed abstracts that contain a total of 84,355 chemical entity mentions labeled manually by expert chemistry literature curators, following annotation guidelines specifically defined for this task. …”
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    The CHEMDNER corpus of chemicals and drugs and its annotation principles
  7. 89967
    “…Journal of Neurochemistry, Journal of Biological Chemistry and Journal of Neuroimmunology were core subject journals in monosialoganglioside studies. …”
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    Scientific literature addressing detection of monosialoganglioside: A 10-year bibliometric analysis☆
  8. 89968
    por Coyne, CP, Jones, Toni, Bear, Ryan
    Publicado 2014
    “…METHODOLOGY: Gemcitabine and epirubicin were covalently bond to anti-EGFR and anti-HER2/neu utilizing a rapid multi-phase synthetic organic chemistry reaction scheme. Determination that 96% or greater gemcitabine or epirubicin content was covalently bond to immunoglobulin fractions following size separation by micro-scale column chromatography was established by methanol precipitation analysis. …”
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    Anti-Neoplastic Cytotoxicity of Gemcitabine-(C(4)-amide)-[anti-EGFR] in Dual-combination with Epirubicin-(C(3)-amide)-[anti-HER2/neu] against Chemotherapeutic-Resistant Mammary Adenocarcinoma (SKBr-3) and the Complementary Effect of Mebendazole
  9. 89969
    “…Advancements in PCR enzymes and buffer chemistry have increased inhibitor tolerance, facilitating PCR directly from crude samples. …”
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    PCR amplification of a triple-repeat genetic target directly from whole blood in 15 minutes as a proof-of-principle PCR study for direct sample analysis for a clinically relevant target
  10. 89970
    “…We hypothesized that the bioreactivity of the NPs would relate to their surface chemistry, charge and size as well as the functional role of their interacting cells in vivo. …”
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    Differential bioreactivity of neutral, cationic and anionic polystyrene nanoparticles with cells from the human alveolar compartment: robust response of alveolar type 1 epithelial cells
  11. 89971
    por Coyne, CP, Jones, Toni, Bear, Ryan
    Publicado 2013
    “…METHODS: A previously described organic chemistry scheme was applied to synthesize a UV-photoactivated gemcitabine intermediate for production of gemcitabine-(C(4)-amide)-[anti-HER2/neu]. …”
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    Anti-Neoplastic Cytotoxicity of Gemcitabine-(C(4)-amide)-[anti-HER2/neu] in Combination with Griseofulvin against Chemotherapeutic-Resistant Mammary Adenocarcinoma (SKBr-3)
  12. 89972
    “…Importantly, the study is the first to investigating binge eating disorder using a dimensional approach, by looking at the different aspects of the disorder, such as behavioral factors, biological factors, brain circuits and chemistry. TRIAL REGISTRATION: Clinical Trials NCT02180984. …”
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    The effects of repetitive transcranial magnetic stimulation in obese females with binge eating disorder: a protocol for a double-blinded, randomized, sham-controlled trial
  13. 89973
    “…BACKGROUND: Fluorescence-enhancing microarray on plasmonic gold film is an attractive alternative to traditional enzyme-linked immunosorbent assay (ELISA) for cytokine detection because of the increased sensitivity. The assay chemistry is similar to an ELISA sandwich assay, but owing to the gold substrate, cytokine measurements are 10 to 100 times more sensitive and can be multiplexed. …”
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    Cytokine detection and simultaneous assessment of rheumatoid factor interference in human serum and synovial fluid using high-sensitivity protein arrays on plasmonic gold chips
  14. 89974
    “…The PCR product was genotyped using Big Dye sequencing chemistry and the sequences were analysed for genotypes and mutations. …”
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    Molecular characterisation of hepatitis B virus in HIV-1 subtype C infected patients in Botswana
  15. 89975
    “…Integrity and functionality of the BBB as well as brain inflammation were characterized using a panel of methods including RT-PCR, immuno-histo chemistry and transporter activity evaluation. RESULTS: Biokinetic analysis revealed Ti biopersistence in liver, lungs and spleen up to one year after TiO(2) NPs administration. …”
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    Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat
  16. 89976
    “…The latest Illumina MiSeq sequencing chemistry has extended the read length to 300 bp, enabling deep profiling of large number of samples in a single paired-end reaction at a fraction of the cost. …”
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    An accurate and efficient experimental approach for characterization of the complex oral microbiota
  17. 89977
    “…Furthermore, this structure change made the chemistry bond of O atom change from the existence of O-Nb, O-B, and O-Al bonds to single O-Al bond and increased the specific value of Al and O. …”
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    Influence of Content of Al(2)O(3) on Structure and Properties of Nanocomposite Nb-B-Al-O films
  18. 89978
    “…However, there is significant scatter between results which may reflect measurement error, but it is also possible that T1 interacts with T2*, or is differentially sensitive to aspects of iron chemistry or other biology. Hurdles to clinical implementation of T1 include the lack of calibration against human myocardial iron concentration, no demonstrated relation to cardiac outcomes, and variation in absolute T1 values between scanners, which makes inter-centre comparisons difficult. …”
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    T1 at 1.5T and 3T compared with conventional T2* at 1.5T for cardiac siderosis
  19. 89979
    “…Blood samples were drawn for complete blood count, clinical chemistry, and inflammatory markers before and every 6 h after inoculation. …”
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    Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?
  20. 89980
    “…Rodent 2-year cancer bioassays, clinical chemistry, and histopathological endpoints are still considered the ‘gold standard’ for detecting substance-induced toxicity in animal models. …”
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    Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes
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