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90621por Caprio, Massimiliano, Moriconi, Eleonora, Camajani, Elisabetta, Feraco, Alessandra, Marzolla, Vincenzo, Vitiello, Laura, Proietti, Stefania, Armani, Andrea, Gorini, Stefania, Mammi, Caterina, Egeo, Gabriella, Aurilia, Cinzia, Fiorentini, Giulia, Tomino, Carlo, Barbanti, Piero“…Anthropometric indexes, urine and blood chemistry were assessed at enrollment, baseline, weeks 4, 8, 12, and 24. …”
Publicado 2023
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90622por Antwan, Agnes S, Rico-Bautista, Elizabeth, Pontillo, Joe, Wang, Shimiao, Johns, Michael, Ramms, Bastian, Fowler, Melissa A, Nguyen, Julie B, Castellanos Gonzalez, Anel A, Fleck, Beth, Retting, Kelsey, Dalvie, Deepak, Betz, Stephen F, Markison, Stacy“…Using iterative medicinal chemistry and pharmacology, Crinetics has identified several potent and orally bioavailable PTH1R antagonists with good drug-like properties. …”
Publicado 2023
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90623por Camajani, Elisabetta, Proietti, Stefania, Persichetti, Agnese, Feraco, Alessandra, Armani, Andrea, Baccaro, Loredana, Lombardo, Mauro, Basciani, Sabrina, Caprio, Massimiliano“…Anthropometric indexes, blood and urine chemistry, and body composition were assessed. Results: Body weight [−8.7±3.3, p<0.001], BMI [−3.2±1.0 kg/m2, p<0.001], blood pressure (-9.1±14.2 mmHg, p=0.002], waist circumference [-6.4±3.0 cm, p<0.001], HOMA index [-4.3±5.8, p<0.001], insulin [-13.6±14.4 µIU, p<0.001], total and low-density lipoprotein cholesterol (LDL) [-49.5±31.2 mg, p<0.001; -36.7±20.6 mg, p<0.001 respectively] and triglycerides [-65.9±93.6 mg, p<0.001] markedly decreased in all participants during the VLCKD phase (day 45). …”
Publicado 2023
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90624por Antanaitis, Ramūnas, Džermeikaitė, Karina, Januškevičius, Vytautas, Šimonytė, Ieva, Baumgartner, Walter“…NEFA levels were assessed using a wet chemistry analyzer. Using the MediSense and FreeStyle Optium H systems, blood samples from the ear were used to measure the levels of BHBA and glucose in plasma. …”
Publicado 2023
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90625“…Compilations of the lake water chemistries show distinct spatial trends and regional variations controlled by groundwater input, climate, and geomorphology. …”
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90626
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90627por Tovmasyan, Artak, Carballal, Sebastian, Ghazaryan, Robert, Melikyan, Lida, Weitner, Tin, Maia, Clarissa G. C., Reboucas, Julio S., Radi, Rafael, Spasojevic, Ivan, Benov, Ludmil, Batinic-Haberle, Ines“…The therapeutic potential of MnPs was assessed via: (i) in vitro ability to prevent spontaneous lipid peroxidation in rat brain homogenate as assessed by malondialdehyde levels; (ii) in vivo O(2)(•–) specific assay to measure the efficacy in protecting the aerobic growth of SOD-deficient Saccharomyces cerevisiae; and (iii) aqueous solution chemistry to measure the reactivity toward major in vivo endogenous antioxidant, ascorbate. …”
Publicado 2014
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90628por Gangadhara, Kishore Lingam, Srivastava, Puneet, Rozenski, Jef, Mattelaer, Henri-Philippe, Leen, Volker, Dehaen, Wim, Hofkens, Johan, Lescrinier, Eveline, Herdewijn, PietEnlace del recurso
Publicado 2014
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90629“…Compared to fragmentation statistics published 40 years ago, the exponential growth in chemistry is mirrored in a nearly eightfold increase in the number of unique chemical fragments; however, this result is clearly an upper bound estimate as earlier studies employed structure sampling approaches and this study shows that a relatively high rate of atom fragments are found in only a single chemical structure (singletons). …”
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90630
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90631por Valdés-Martiní, José R., Marrero-Ponce, Yovani, García-Jacas, César R., Martinez-Mayorga, Karina, Barigye, Stephen J., Vaz d‘Almeida, Yasser Silveira, Pham-The, Hai, Pérez-Giménez, Facundo, Morell, Carlos A.“…This program was developed in Java v1.7 using the Chemistry Development Kit library (version 1.4.19). …”
Publicado 2017
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90632por Delgado-Enciso, Ivan, Paz-Garcia, Juan, Valtierra-Alvarez, Jose, Preciado-Ramirez, Jorge, Almeida-Trinidad, Roman, Guzman-Esquivel, Jose, Mendoza-Hernandez, Martha A., Garcia-Vega, Alberto, Soriano-Hernandez, Alejandro D., Cortes-Bazan, Jose L., Galvan-Salazar, Hector R., Cabrera-Licona, Ariana, Rodriguez-Sanchez, Iram P., Martinez-Fierro, Margarita L., Delgado-Enciso, Josuel, Paz-Michel, Brenda“…Complete blood count and blood chemistry parameters were determined in the BIOF2 group before treatment, at 72 h, and at months 1, 3, 6, and 12. …”
Publicado 2018
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90633por Tran, Cam Tuan, Felber Medlin, Loyse, Lama, Nicola, Taranu, Brindusa, Ng, Weeteck, Haziza, Christelle, Picavet, Patrick, Baker, Gizelle, Lüdicke, Frank“…Safety assessments included adverse events and serious adverse events, body weight, vital signs, spirometry, electrocardiogram, clinical chemistry, hematology and urine analysis safety panel, physical examination, and concomitant medications. …”
Publicado 2019
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90634por Zeng, Xin, Zhu, Min, Liu, Xiaohong, Chen, Xuanmin, Yuan, Yujia, Li, Lan, Liu, Jingping, Lu, Yanrong, Cheng, Jingqiu, Chen, Younan“…Sprague–Dawley (SD) rats were fed with high fat diet (HFD) for 16 w, then, HFD was half replaced by olive oil to observe the protective effects of olive oil. The blood chemistry were analyzed, and the liver histology and the expressions of related genes and proteins were determined in the liver tissues. …”
Publicado 2020
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90635por Sombié, Herman Karim, Sorgho, Abel Pegdwendé, Kologo, Jonas Koudougou, Ouattara, Abdoul Karim, Yaméogo, Sakinata, Yonli, Albert Théophane, Djigma, Florencia Wendkuuni, Tchelougou, Daméhan, Somda, Dogfounianalo, Kiendrébéogo, Isabelle Touwendpoulimdé, Bado, Prosper, Nagalo, Bolni Marius, Nagabila, Youssoufou, Adoko, Enagnon Tiémoko Herman Donald, Zabsonré, Patrice, Millogo, Hassanata, Simporé, Jacques“…Biochemical parameters were measured using chemistry analyzer CYANExpert 130. RESULTS: Chi-squared test shows that GSTT1-null (OR = 1.82; p = 0.001) and GSTM1-active/GSTT1-null genotypes (OR = 2.33; p < 0.001) were significantly higher in cases than controls; the differences were not significant for GSTM1-null, GSTM1-null/GSTT1-active and GSTM1-null/GSTT1-null (p > 0.05). …”
Publicado 2020
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90636por Lee, D.S., Pitari, G., Grewe, V., Gierens, K., Penner, J.E., Petzold, A., Prather, M.J., Schumann, U., Bais, A., Berntsen, T., Iachetti, D., Lim, L.L., Sausen, R.“…Despite the progress made on modelling aviation's impacts on tropospheric chemistry, there remains a significant spread in model results. …”
Publicado 2010
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90637“…RESULTS: Evolutionary selection favoured increasing strand length to maximize auto-catalytic function in RNA and polymer stability in double stranded DNA (Krishnamurthy, Chemistry 24:16708-16715, 2018; Szathmary, Nat Rev Genet 4:995-1001, 2003). …”
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90638por Fossler, Michael J., Schmith, Virginia, Greene, Stephen A., Lohmer, Lauren, Kramer, Michael S., Arscott, Kelly, James, Ian E., Demitrack, Mark A.“…There were no clinically relevant changes in physical examination, hematology, clinical chemistry, urinalysis, suicidal ideation, or vital signs, with the exception of orthostatic changes in some subjects. …”
Publicado 2020
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90639por Marchant, Wendy G., Legarrea, Saioa, Smeda, John R., Mutschler, Martha A., Srinivasan, Rajagopalbabu“…This study evaluated acylsugar-producing tomato lines with quantitative trait loci (QTL) containing introgressions from Solanum pennellii LA716, known to alter acylsugars’ levels or chemistry. Evaluated acylsugar-producing lines were the benchmark line CU071026, QTL6/CU071026—a CU071026 sister line with QTL6, and three other CU071026 sister lines with varying QTLs—FA2/CU71026, FA7/CU071026, and FA2/FA7/CU071026. …”
Publicado 2020
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90640por Thakur, Nanamika, Kupani, Manu, Mannan, Rashim, Pruthi, Archna, Mehrotra, Sanjana“…Genotyping was done with Taqman chemistry. In addition, an updated meta-analysis was performed. …”
Publicado 2021
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