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91161por Nzimande, Bruce, Makhwitine, John P., Mkhwanazi, Nompumelelo P., Ndlovu, Sizwe I.“…Despite the potential of the fungal kingdom as a source for diverse chemistries that can yield novel HIV therapies, there are few comprehensive reports on the progress made thus far in the search for fungal species with the capacity to produce anti-HIV compounds. …”
Publicado 2023
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91162Impacts of Nanobubbles in Pore Water on Heavy Metal Pollutant Release from Contaminated Soil Columns“…The flow rate used in column tests was optimized to achieve proper soil fluidization and metal desorption or release. The leachate chemistries were monitored to assess the effect of NBs on conductivity, pH, oxidation–reduction potential (ORP), and dissolved oxygen (DO). …”
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91163“…Yet, this information may depend upon the expert-defined space, and might be subjective and biased toward the chemistries they get used to. Most importantly, these practices are often informatively incomplete since they are often compromised by a try-and-error cycle, and although they depict what kind of substructures are suitable for the replacement occurrence, they fail to explain the driving forces to support such interchanges. …”
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91164por Xu, Yang, Ferguson, Tammy, Masuda, Kazuya, Siddiqui, Mohammad Adnan, Smith, Kelsi Poole, Vest, Olivia, Brooks, Brad, Zhou, Ziyou, Obliosca, Judy, Kong, Xiang-Peng, Jiang, Xunqing, Yamashita, Masahiro, Moriya, Tsuji, Tison, Christopher“…As a result, Luna Labs is developing a short carbon nanotube-based delivery platform (NanoVac) that can co-deliver mRNA and HIV-1 glycoproteins to the immune system efficiently with negligible toxicity. Surface chemistries of NanoVac were optimized to guide antigen/mRNA loading density and presentation. …”
Publicado 2023
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91165por Srivastava, Ananya, Dkhar, Daphika S., Singh, Nandita, Azad, Uday Pratap, Chandra, Pranjal“…Despite the difficulty of production, borophene may be immobilized utilizing chemistries, be functionalized on a flexible substrate, and be controlled over electro-optical properties to create a highly sensitive biosensor system that could be used for point-of-care diagnostics. …”
Publicado 2023
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91166por Frost, Lorraine, Tully, Matthew, Dixon, Linda, Hicks, Hayley M., Bennett, Jessica, Stokes, Isobel, Marsella, Laura, Gubbins, Simon, Batten, Carrie“…The aim of this study was to establish the biocidal effects of twenty-four commercially available disinfectants including oxidizing agents, acids, aldehydes, formic acids, phenol, and mixed-class chemistries against ASFV. The products were prepared according to the manufacturer’s instructions and a suspension assay was performed with ASFV strain, BA71V using Vero cells (African green monkey cells) to test efficacy in reducing ASFV infection of cells. …”
Publicado 2023
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91167“…This pronounced effect demonstrates that steric moieties can be a powerful tool for kinetic control in strand displacement networks while also being more broadly informative of DNA structural assembly in both DNA-based therapeutic and diagnostic applications that possess elements of steric hindrance through DNA functionalization with an assortment of chemistries.…”
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91168por Vonada, Anne, Wakefield, Leslie, Martinez, Michael, Harding, Cary O., Grompe, Markus, Tiyaboonchai, Amita“…Cypor-deficient hepatocytes expanded from <1% to ~14% in corrected animals, and they showed no abnormalities in blood chemistries, liver histology, or drug metabolism. We conclude that APAP-mediated selection of transplanted hepatocytes is a potential therapeutic for PKU with long-term efficacy and a favorable safety profile.…”
Publicado 2023
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91169por Noreen, Saadia, Ballard, David, Mehmood, Tahir, Khan, Arif, Khalid, Tanveer, Rakha, Allah“…The SNaPshot™ multiplex chemistries, capillary electrophoresis methods and GeneMapper™ software were used for obtaining genotypic data. …”
Publicado 2022
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91170por Buchner, Thomas J. K., Rogler, Simon, Weirich, Stefan, Armati, Yannick, Cangan, Barnabas Gavin, Ramos, Javier, Twiddy, Scott T., Marini, Davide M., Weber, Aaron, Chen, Desai, Ellson, Greg, Jacob, Joshua, Zengerle, Walter, Katalichenko, Dmitriy, Keny, Chetan, Matusik, Wojciech, Katzschmann, Robert K.“…This contactless process allows us to use continuously curing chemistries and, therefore, print a broader range of material families and elastic moduli. …”
Publicado 2023
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91171por Winnenburg, Rainer, Baldwin, Thomas K., Urban, Martin, Rawlings, Chris, Köhler, Jacob, Hammond-Kosack, Kim E.“…As such, PHI-base is a valuable resource for the discovery of candidate targets in medically and agronomically important fungal and Oomycete pathogens for intervention with synthetic chemistries and natural products. Each entry in PHI-base is curated by domain experts and supported by strong experimental evidence (gene/transcript disruption experiments) as well as literature references in which the experiments are described. …”
Publicado 2006
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91172“…Identification of optimal ASO chemistries for targeting miRNAs is therefore of great interest. …”
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91173por Sanders, V M, Kauffmann, B M, White, K L, Douglas, K A, Barnes, D W, Sain, L E, Bradshaw, T J, Borzelleca, J F, Munson, A E“…Male mice demonstrated a dose-related hepatomegaly accompanied by significant changes in serum chemistries and hepatic microsomal parameters. The females did not demonstrate the hepatomegaly observed in males, but did show alterations in hepatic microsomal parameters. …”
Publicado 1982
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91174por Munson, A E, Sain, L E, Sanders, V M, Kauffmann, B M, White, K L, Page, D G, Barnes, D W, Borzelleca, J F“…Parameters observed included body and organ weights, histopathology, hematology, clinical chemistries, and hepatic microsomal enzyme activities. …”
Publicado 1982
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91175“…Previous studies of pyrimidine-rich methoxypsoralen–modified TFOs indicated that the TFO inhibits cleavage by UvrABC. Because different chemistries may alter the processing of TFO-directed ICLs, we investigated the effect of another type of triplex formed by purine-rich TFOs on the processing of 4′-(hydroxymethyl)-4,5′,8-trimethylpsoralen (HMT) ICLs by the UvrABC nuclease. …”
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91176por Wilson, C. E., van Blitterswijk, C. A., Verbout, A. J., Dhert, W. J. A., de Bruijn, J. D.“…The macro- and micro-architectures of the scaffolds were characterized as well as the influence of the manufacturing method on the chemistries of the calcium phosphate compositions. The structural characteristics of the resulting scaffolds were remarkably similar. …”
Publicado 2010
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91177“…Nevertheless, the color multiplexing, probe design, and cross-platform compatibility remain to be limited by using existing probe chemistries. We hereby explored two dual-labeled, self-quenched probes, TaqMan and shared-stem molecular beacons, in their ability to conduct FMCA. …”
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91178“…[Image: see text] Unnatural amino acids (Uaas) can be translationally incorporated into proteins in vivo using evolved tRNA/aminoacyl-tRNA synthetase (RS) pairs, affording chemistries inaccessible when restricted to the 20 natural amino acids. …”
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91179“…Currently these immunoconjugates are prepared by rather unspecific coupling chemistries, resulting in heterogeneous products. As the drug load is a key parameter for the antitumor activity, site-specific strategies are desired. …”
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91180“…Given tunable magnetic properties and various surface chemistries from the coating materials, most applications of engineered magnetic nanoparticles take advantages of their superb MRI contrast enhancing capability as well as surface functionalities. …”
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