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  1. 681
    “…In recent years, the need for sophisticated human in vitro models for integrative biology has motivated the development of organ-on-a-chip platforms. Organ-on-a-chip devices are engineered to mimic the mechanical, biochemical and physiological properties of human organs; however, there are many important considerations when selecting or designing an appropriate device for investigating a specific scientific question. …”
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    Review of Design Considerations for Brain-on-a-Chip Models
  2. 682
    “…The IOC was interfaced with a state-of-the-art on-chip LSPR sensing platform to monitor the in situ insulin secretion. …”
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    In Situ LSPR Sensing of Secreted Insulin in Organ-on-Chip
  3. 683
    por Burg, David, Ausubel, Jesse H.
    Publicado 2021
    “…Gordon Moore famously observed that the number of transistors in state-of-the-art integrated circuits (units per chip) increases exponentially, doubling every 12–24 months. …”
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    Moore’s Law revisited through Intel chip density
  4. 684
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    Resolution-Enhancing Structure for the Electric Field Microsensor Chip
  5. 685
    “…Here, we show intracellular Ni-based chips with magnetic capabilities to allow cell enrichment. …”
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    Integrating magnetic capabilities to intracellular chips for cell trapping
  6. 686
    “…WHAT IS KNOWN ALREADY: Organ-on-a-chip, a multi-channel 3D microfluidic cell culture system, is widely used to investigate physiologically relevant responses of organ systems. …”
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    Three-dimensional microengineered vascularised endometrium-on-a-chip
  7. 687
    “…As an application, we also fabricate a chip that can control bubble flow based on this microvalve. …”
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    A Novel On-Chip Liquid-Metal-Enabled Microvalve
  8. 688
    por Luttge, Regina
    Publicado 2021
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    Editorial for the Special Issue on Microfluidic Brain-on-a-Chip
  9. 689
    “…[Image: see text] Tumor-on-chip devices are becoming ideal platforms to recreate in vitro the particular physiological microenvironment of interest for onco-nanomedicine testing and development. …”
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    Microvessel-on-Chip Fabrication for the In Vitro Modeling of Nanomedicine Transport
  10. 690
    “…Organ-on-chip (OoC) and multi-organs-on-chip (MOoC) systems have the potential to play an important role in drug discovery, disease modeling, and personalized medicine. …”
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    Facilitating implementation of organs-on-chips by open platform technology
  11. 691
    “…In this paper, we review recent optofluidic lab-on-chip systems and techniques used for microalgal detection and characterization. …”
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    The Fusion of Microfluidics and Optics for On-Chip Detection and Characterization of Microalgae
  12. 692
    “…The system includes a polymeric microfluidic chip containing magnetic beads loaded with copper to exploit the preferential interaction of tetracycline with divalent ions. …”
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    On-Chip Purification of Tetracyclines Based on Copper Ions Interaction
  13. 693
    por Ding, Shuang, Zhang, Haijun, Wang, Xuemei
    Publicado 2021
    “…In the past decade, human organ-on-a-chip (OOC) platforms—including lung-on-a-chip (LOC)—have emerged rapidly, with the ability to reproduce the in vivo features of organs or tissues based on their three-dimensional (3D) structures. …”
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    Microfluidic-Chip-Integrated Biosensors for Lung Disease Models
  14. 694
    “…However, PS is only rarely used in microfluidic prototyping, since the structuring of PS is mainly performed using industrial-scale replication processes. So far, microfluidic chips in PS have not been accessible to rapid prototyping via 3D printing. …”
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    Fused Deposition Modeling of Microfluidic Chips in Transparent Polystyrene
  15. 695
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    Thermo-optically induced transparency on a photonic chip
  16. 696
    “…Microfluidic, or lab-on-a-chip, platforms address the complexity issues of conventional 3D models regarding cell numbers and functional connectivity. …”
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    Tissue engineering of the retina: from organoids to microfluidic chips
  17. 697
    por Dér, András
    Publicado 2021
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    Special Issue on Versatile Organ-on-a-Chip Devices
  18. 698
    “…Organ on chip (OOC) has emerged as a major technological breakthrough and distinct model system revolutionizing biomedical research and drug discovery by recapitulating the crucial structural and functional complexity of human organs in vitro. …”
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    Organ on Chip Technology to Model Cancer Growth and Metastasis
  19. 699
    “…We suggest that a photonic integrated chip installed on the interior surface of the skull may enable a new form of extraction of the relevant features from the UPE signals. …”
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    Are Brain–Computer Interfaces Feasible With Integrated Photonic Chips?
  20. 700
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    Noise Power Minimization in CMOS Brain-Chip Interfaces
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