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“…To address this issue, we developed an improved brain cancer chip with a diffusion prevention mechanism that blocks drugs crossing from one channel to another. …”
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“…Existing on-chip spectrometer designs, however, are limited in spectral channel count and signal-to-noise ratio. …”
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“…During the preparation of on-chip PCR, a set of primers were immobilized on a slide and other sets were in an emulsion system. …”
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“…Moreover, microfluidic chips are designed and fabricated for applications in cell separations such as circulating tumor cell (CTC) chips. …”
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“…This review describes existing biomimetic immune organs-on-chip, highlights their physiological relevance to drug development and discovery and emphasizes the need for developing comprehensive immune system-on-chip models. …”
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“…The success of labs- and organs-on-chips as transformative technologies in the biomedical arena relies on our capacity of solving some current challenges related to their design, modeling, manufacturability, and usability. …”
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“…With advantageous features such as minimizing the cost, time, and sample size requirements, organ-on-a-chip (OOC) systems have garnered enormous interest from researchers for their ability for real-time monitoring of physical parameters by mimicking the in vivo microenvironment and the precise responses of xenobiotics, i.e., drug efficacy and toxicity over conventional two-dimensional (2D) and three-dimensional (3D) cell cultures, as well as animal models. …”
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“…Chromatin immunoprecipitation (ChIP) is an assay developed in order to define the dynamic nature of transcription processes. …”
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“…This study reports a microreactor chip for oligo synthesis. By incorporating silica beads in the microreactors, the surface area of the solid substrate for oligo synthesis increases significantly in each microreactor. …”
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“…Based on the fact that sweat is mainly composed of moisture and salt which is much more abundant than other trace ions in sweat, a new route is proposed to realize wearable sweat sensors using CdSSe nanowire-chips coated with a polyimide (PI) membrane. RESULTS: Firstly, the composition-graded CdS(1−x)Se(x) (x = 0–1) nanowire-chip based sensor shows good photo-sensitivity and stress sensitivity which induces linear humidity dependent conductivity. …”
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“…Organ-on-a-chip (OoCs) platforms could revolutionize drug discovery and might ultimately become essential tools for precision therapy. …”
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“…Using Optimal Control Theory (OCT), we design fast ramps for the controlled transport of Bose-Einstein condensates with atom chips’ magnetic traps. These ramps are engineered in the context of precision atom interferometry experiments and support transport over large distances, typically of the order of 1 mm, i.e. about 1,000 times the size of the atomic clouds, yet with durations not exceeding 200 ms. …”
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“…However, by combining recently developed human induced pluripotent stem cell (hiPSC) technology and organ-on-chip technology, in vitro intestine-on-chip systems can now be developed that integrate the genetic background of complex diseases, the different interacting cell types involved in disease pathology, and the modulating environmental factors such as gluten and the gut microbiome. …”
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“…The microchannel is the critical element of a microfluidic chip, and thus the microchannel replicability directly affects the performance of the microfluidic chip. …”
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“…The patient underwent open heart surgery and the thrombotic rod shape chip that was embedded in anterior tricuspid leaflet was removed and then TV was repaired.…”
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“…Microfluidic systems can provide the tools to improve and refine existing synthetic systems because they allow control and manipulation of liquids on a micro- and nanoscale. In addition, chip-based approaches are predisposed for synthetic biology applications since they present an opportune technological toolkit capable of fully automated high throughput and content screening under low reagent consumption. …”
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“…Here we produce and encode photonic graph states on a mass-manufactured chip, using four on-chip-generated photons. We programmably generate all types of four-photon graph state, implementing a basic measurement-based protocol, and measure high-visibility heralded interference of the chip’s four photons. …”
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