“…But the use of nanoscopy in histopathology assessment is very limited mostly due to the low throughput of traditional nanoscopic techniques. So far, Chip-nanoscopy, nanoscopy in which sample illumination is performed by an integrated photonic chip instead of bulk optics, has been shown to provide an enhanced field of view and throughput for cell biology. …”
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“…Our approach provides a random wave-meter on chip device with accurate calibration and enhanced robustness against environmental fluctuations. …”
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“…OBJECTIVES: The aim of this study was to examine the association between mutations associated with CHIP (CHIP-related mutations) identified in patients at AML diagnosis and the risk for cardiovascular events (CVEs). …”
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“…A microfluidic chip based on capillary infiltration was designed to detect tumor markers. …”
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“…However, a pure PP material microfluidic chip has rarely been reported. Herein, a simple and rapid method has been developed to fabricate a pure PP microfluidic chip by a thermal bonding process using a PP film and PP substrate. …”
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“…This “build and transfer” concept could, in future, also be adapted for the layer-by-layer construction of organs-on-chip in microtitre formats.…”
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“…We demonstrate, for the first time, the integrated generation and detection of a hyperpolarized metabolite on a microfluidic chip. The metabolite [1-(13)C]fumarate is produced in a nuclear hyperpolarized form by (i) introducing para-enriched hydrogen into the solution by diffusion through a polymer membrane, (ii) reaction with a substrate in the presence of a ruthenium-based catalyst, and (iii) conversion of the singlet-polarized reaction product into a magnetized form by the application of a radiofrequency pulse sequence, all on the same microfluidic chip. …”
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“…Through binding with the double antibodies sandwich immunoassay, the proposed sensor chip is confirmed to be a candidate for sensing the aforementioned toxins. …”
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“…We developed surface-optimized polydimethylsiloxane (PDMS) biochip platforms for uniform spheroid formation on-chip. These biochips were surface modified with 10% bovine serum albumin (BSA) to effectively suppress cell adhesion on the PDMS surface. …”
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“…However, controlled THz generation, along with transport and detection, has remained a challenge especially for chip-scale devices due to low-coupling efficiency and unavoidable absorption losses. …”
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“…Here, we demonstrate a multi-skilled diffractive neural network based on a metasurface device, which can perform on-chip multi-channel sensing and multitasking in the visible. …”
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“…In this work, we experimentally demonstrate a concealable PUF at the chip level with an integrated memristor array and peripherals. …”
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“…Therefore, surface hydrophilic modification for such chips is necessary to improve the rapidity and sensitivity of the system. …”
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“…Meanwhile, traditional on-chip copper interconnects reach their physical limitation of resistivity and reliability and may no longer be able to keep pace with a processor’s data throughput. …”
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“…Furthermore, the proposed on-chip temperature compensation circuit also applies to multi-stage cascaded microwave/mm-wave power amplifiers.…”
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“…On-chip polarimeters are highly desirable for the next-generation ultra-compact optical and optoelectronic systems. …”
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“…Muscle-on-chip devices aim to recapitulate the physiological characteristics of in vivo muscle tissue and so maintaining levels of oxygen transported to cells is essential for cell survival and for providing the normoxic conditions experienced in vivo. …”
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“…To date, research in the field of on-chip optical analog computing has mainly focused on classical mathematical operations. …”
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“…In this research, we integrated skin extracellular matrix and skin cells into a microfluidic chip to construct a biomimetic “interface-controlled-skin-on-chip” system (IC-SoC), which constructed a stable air–liquid interface (ALI) and necessary mechanical signals for the development of human skin equivalents. …”
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“…We report analysis of phosphatase activity and inhibition on droplet-based microfluidic chips. Phosphatases are such attractive potential drug targets because abnormal phosphatase activity has been implicated in a variety of diseases including cancer, neurological disorders, diabetes, osteoporosis, and obesity. …”
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