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1221“…Recent progress in massively parallel sequencing platforms has allowed for genome-wide measurements of DNA-associated proteins using a combination of chromatin immunoprecipitation and sequencing (ChIP-seq). While a variety of methods exist for analysis of the established microarray alternative (ChIP-chip), few approaches have been described for processing ChIP-seq data. …”
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1222por Lee, Yun-Shien, Chen, Chun-Houh, Tsai, Chi-Neu, Tsai, Chia-Lung, Chao, Angel, Wang, Tzu-Hao“…RNA quality, RNA labeling efficiency, hybridization procedures and data-mining tools can all contribute variations in each laboratory. In Affymetrix GeneChips, about 11–20 different 25-mer oligonucleotides are used to measure the level of each transcript. …”
Publicado 2009
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1223
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1224“…We further show that LRRK2 forms a complex with overexpressed and endogenous CHIP and Hsp90. Our data indicates that the destabilization of LRRK2 by CHIP is due to ubiquitination and proteasome-dependent degradation. …”
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1225por Odenthal, M, Barta, N, Lohfink, D, Drebber, U, Schulze, F, Dienes, H P, Baldus, S E“…In conclusion, microfluidic chip technology is a simple and reliable approach for MSI detection that allows label-free and very fast analysis of microsatellite amplicons.…”
Publicado 2009
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1226“…ChIP-Seq technology, which combines chromatin immunoprecipitation (ChIP) with massively parallel sequencing, is rapidly replacing ChIP-on-chip for the genome-wide identification of transcription factor binding events. …”
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1227por Shi, Wei, Banerjee, Ashish, Ritchie, Matthew E, Gerondakis, Steve, Smyth, Gordon K“…BACKGROUND: Illumina Sentrix-6 Whole-Genome Expression BeadChips are relatively new microarray platforms which have been used in many microarray studies in the past few years. …”
Publicado 2009
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1228por Macrae, Duncan, Pappachan, John, Grieve, Richard, Parslow, Roger, Nadel, Simon, Schindler, Margrid, Baines, Paul, Fortune, Peter-Marc, Slavik, Zdenek, Goldman, Allan, Truesdale, Ann, Betts, Helen, Allen, Elizabeth, Snowdon, Claire, Percy, Deborah, Broadhead, Michael, Quick, Tara, Peters, Mark, Morris, Kevin, Tasker, Robert, Elbourne, DianaEnlace del recurso
Publicado 2010
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1229
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1230“…We introduce the use of a birefringent crystal with lensless digital holography to create an on-chip differential interference contrast (DIC) microscope. …”
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1232por Cairns, Jonathan, Spyrou, Christiana, Stark, Rory, Smith, Mike L., Lynch, Andy G., Tavaré, Simon“…Motivation: Identification of genomic regions of interest in ChIP-seq data, commonly referred to as peak-calling, aims to find the locations of transcription factor binding sites, modified histones or nucleosomes. …”
Publicado 2011
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1233“…While high-throughput methods like ChIP-Seq have led to a flood of high-quality data about these epigenomic domains, there remain important analysis problems that are not adequately solved by current analysis tools. …”
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1234por Ye, Tao, Krebs, Arnaud R., Choukrallah, Mohamed-Amin, Keime, Celine, Plewniak, Frederic, Davidson, Irwin, Tora, Laszlo“…In a single experiment, chromatin immunoprecipitation combined with high throughput sequencing (ChIP-seq) provides genome-wide information about a given covalent histone modification or transcription factor occupancy. …”
Publicado 2011
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1235por Bailey, Timothy L.“…Motivation: Transcription factor (TF) ChIP-seq datasets have particular characteristics that provide unique challenges and opportunities for motif discovery. …”
Publicado 2011
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1236“…Future advancements of these microfluidic strategies will lead toward translational lab-on-a-chip systems for a wide spectrum of biological engineering applications.…”
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1237“…Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) allows researchers to determine the genome-wide binding locations of individual transcription factors (TFs) at high resolution. …”
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1238por Nagarah, John MichaelEnlace del recurso
Publicado 2011
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1239“…The two-chip microsystem consists of a MEMS chip for sensing the external acceleration and a CMOS chip for signal processing. …”
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1240“…Microfluidics-based lab-on-chip (LOC) systems are an active research area that is revolutionising high-throughput sequencing for the fast, sensitive and accurate detection of a variety of pathogens. …”
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