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  1. 1321
    “…For on-chip interconnects, an ideal light source should have an ultralow energy consumption per bandwidth (operating en-ergy) as well as sufficient output power for error-free detection. …”
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    Ultrahigh-speed Si-integrated on-chip laser with tailored dynamic characteristics
  2. 1322
    “…There are few computational methods comparing changes in ChIP-seq signals with replicates. Moreover, none of these previous approaches addresses ChIP-seq specific experimental artefacts arising from studies with biological replicates. …”
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    Differential peak calling of ChIP-seq signals with replicates with THOR
  3. 1323
    por Jones, David R
    Publicado 2016
    “…We met him at the Organ-on-a-chip Europe 2016 conference in Cambridge (UK), where he presented ‘A UK Regulatory View on the Acceptability of Organ on a Chip Data’.…”
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    Looking to the future of organ-on-chip and toxicity assessment: a regulator's opinion
  4. 1324
    “…Integrating this OFS with a polymethylmethacrylate (PMMA)-based microfluidic chip, the SPR spectra for liquids with different refractive indices are recorded. …”
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    Integration of Curved D-Type Optical Fiber Sensor with Microfluidic Chip
  5. 1325
    “…Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is an important tool for studying gene regulatory proteins, such as transcription factors and histones. …”
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    Features that define the best ChIP-seq peak calling algorithms
  6. 1326
    “…In this review, the concept, design, performance, and a functional demonstration of multifunctional complementary metal-oxide-semiconductor (CMOS) image sensors dedicated to on-chip biosensing applications are described. We developed a sensor architecture that allows flexible configuration of a sensing pixel array consisting of optical and electric sensing pixels, and designed multifunctional CMOS image sensors that can sense light intensity and electric potential or apply a voltage to an on-chip measurement target. …”
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    Optical and Electric Multifunctional CMOS Image Sensors for On-Chip Biosensing Applications
  7. 1327
    “…In addition, a factorial experimental design with analysis of variance is proposed to optimize chip stacking structure reliability with four factors: chip thickness, substrate thickness, CTE, and E-value. …”
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    Development of Equivalent Material Properties of Microbump for Simulating Chip Stacking Packaging
  8. 1328
    por van den Berg, Marten E., Warren, Helen R., Cabrera, Claudia P., Verweij, Niek, Mifsud, Borbala, Haessler, Jeffrey, Bihlmeyer, Nathan A., Fu, Yi-Ping, Weiss, Stefan, Lin, Henry J., Grarup, Niels, Li-Gao, Ruifang, Pistis, Giorgio, Shah, Nabi, Brody, Jennifer A., Müller-Nurasyid, Martina, Lin, Honghuang, Mei, Hao, Smith, Albert V., Lyytikäinen, Leo-Pekka, Hall, Leanne M., van Setten, Jessica, Trompet, Stella, Prins, Bram P., Isaacs, Aaron, Radmanesh, Farid, Marten, Jonathan, Entwistle, Aiman, Kors, Jan A., Silva, Claudia T., Alonso, Alvaro, Bis, Joshua C., de Boer, Rudolf, de Haan, Hugoline G., de Mutsert, Renée, Dedoussis, George, Dominiczak, Anna F., Doney, Alex S. F., Ellinor, Patrick T., Eppinga, Ruben N., Felix, Stephan B., Guo, Xiuqing, Hagemeijer, Yanick, Hansen, Torben, Harris, Tamara B., Heckbert, Susan R., Huang, Paul L., Hwang, Shih-Jen, Kähönen, Mika, Kanters, Jørgen K., Kolcic, Ivana, Launer, Lenore J., Li, Man, Yao, Jie, Linneberg, Allan, Liu, Simin, Macfarlane, Peter W., Mangino, Massimo, Morris, Andrew D., Mulas, Antonella, Murray, Alison D., Nelson, Christopher P., Orrú, Marco, Padmanabhan, Sandosh, Peters, Annette, Porteous, David J., Poulter, Neil, Psaty, Bruce M., Qi, Lihong, Raitakari, Olli T., Rivadeneira, Fernando, Roselli, Carolina, Rudan, Igor, Sattar, Naveed, Sever, Peter, Sinner, Moritz F., Soliman, Elsayed Z., Spector, Timothy D., Stanton, Alice V., Stirrups, Kathleen E., Taylor, Kent D., Tobin, Martin D., Uitterlinden, André, Vaartjes, Ilonca, Hoes, Arno W., van der Meer, Peter, Völker, Uwe, Waldenberger, Melanie, Xie, Zhijun, Zoledziewska, Magdalena, Tinker, Andrew, Polasek, Ozren, Rosand, Jonathan, Jamshidi, Yalda, van Duijn, Cornelia M., Zeggini, Eleftheria, Jukema, J. Wouter, Asselbergs, Folkert W., Samani, Nilesh J., Lehtimäki, Terho, Gudnason, Vilmundur, Wilson, James, Lubitz, Steven A., Kääb, Stefan, Sotoodehnia, Nona, Caulfield, Mark J., Palmer, Colin N. A., Sanna, Serena, Mook-Kanamori, Dennis O., Deloukas, Panos, Pedersen, Oluf, Rotter, Jerome I., Dörr, Marcus, O'Donnell, Chris J., Hayward, Caroline, Arking, Dan E., Kooperberg, Charles, van der Harst, Pim, Eijgelsheim, Mark, Stricker, Bruno H., Munroe, Patricia B.
    Publicado 2017
    “…This study aims to discover new genetic loci associated with heart rate from Exome Chip meta-analyses. Heart rate was measured from either elecrtrocardiograms or pulse recordings. …”
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    Discovery of novel heart rate-associated loci using the Exome Chip
  9. 1329
    “…In this study, we developed a facile gold nanozyme-based paper chip (AuNZ-PAD) for Hg(2+) detection. This device has the advantages of being simple, rapid, cost effective, sensitive, selective, high throughput, and applicable to onsite detection. …”
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    Gold nanozyme-based paper chip for colorimetric detection of mercury ions
  10. 1330
    “…We also demonstrate the ease and utility of combining on-chip technology with previously fractionated venoms for detection of specific individual toxin proteins. …”
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    Venom On-a-Chip: A Fast and Efficient Method for Comparative Venomics
  11. 1331
    “…We demonstrate NMR spectroscopy of picoliter-volume solutions using a nanostructured diamond chip with dense, high-aspect-ratio nanogratings, enhancing the surface area by 15 times. …”
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    Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip
  12. 1332
    “…Since the advent of integrated quantum nanophotonics different material platforms based on III–V nanostructures-, colour centers-, and nonlinear waveguides as on-chip light sources have been investigated. Each platform has unique advantages and limitations; however, all implementations face major challenges with filtering of individual quantum states, scalable integration, deterministic multiplexing of selected quantum emitters, and on-chip excitation suppression. …”
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    On-chip single photon filtering and multiplexing in hybrid quantum photonic circuits
  13. 1333
    “…This will enable a shift towards quantitative studies on three-dimensional cultures, under dynamic conditions, with implications for stem cells, organs-on-chips, or cancer research.…”
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    Multiscale cytometry and regulation of 3D cell cultures on a chip
  14. 1334
    “…The current developmental trends and promising research directions in the establishment of microfluidic chips for the capture and detection of CTCs are also discussed.…”
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    Nanomaterial-based Microfluidic Chips for the Capture and Detection of Circulating Tumor Cells
  15. 1335
    “…We demonstrate the central element of an all-optical calculator, a photonic abacus, which provides multistate compute-and-store operation by integrating functional phase-change materials with nanophotonic chips. With picosecond optical pulses we perform the fundamental arithmetic operations of addition, subtraction, multiplication, and division, including a carryover into multiple cells. …”
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    Calculating with light using a chip-scale all-optical abacus
  16. 1336
    “…RESULTS: We have designed software called Time-Dependent ChIP-Sequencing Analyser (TDCA), which is the first program to automate analysis of time-dependent ChIP-seq data by fitting to sigmoidal curves. …”
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    Software for rapid time dependent ChIP-sequencing analysis (TDCA)
  17. 1337
    “…On-chip energy storage and management will have transformative impacts in developing advanced electronic platforms with built-in energy needs for operation of integrated circuits driving a microprocessor. …”
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    On-chip integrated vertically aligned carbon nanotube based super- and pseudocapacitors
  18. 1338
    “…BACKGROUND: Chromatin immunoprecipitation-sequencing (ChIP-seq) is a widely used epigenetic approach for investigating genome-wide protein-DNA interactions in cells and tissues. …”
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    Purification of nanogram-range immunoprecipitated DNA in ChIP-seq application
  19. 1339
    “…In addition, microfluidic cell assays and organ-on-chip models offer new potential approaches for CVD and cancer diagnosis. …”
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    Lab-on-a-Chip Platforms for Detection of Cardiovascular Disease and Cancer Biomarkers
  20. 1340
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    Author Correction: A chip-integrated coherent photonic-phononic memory
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