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421por Guo, Henan, Tong, Yucui, Cheng, Junhao, Abbas, Zaheer, Li, Zhongxuan, Wang, Junyong, Zhou, Yichen, Si, Dayong, Zhang, Rijun“…In this review, we briefly describe the development of the DR/MDR as well as the classical mechanisms (accumulation of the resistant genes). …”
Publicado 2022
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422“…Self-sustained oscillations can directly absorb energy from the constant environment to maintain its periodic motion by self-regulating. As a classical mechanical instability phenomenon, the Euler compression rod can rapidly release elastic strain energy and undergo large displacement during buckling. …”
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423por Dordet-Frisoni, Emilie, Sagné, Eveline, Baranowski, Eric, Breton, Marc, Nouvel, Laurent Xavier, Blanchard, Alain, Marenda, Marc Serge, Tardy, Florence, Sirand-Pugnet, Pascal, Citti, Christine“…These findings challenged the classical mechanisms proposed for other bacteria in which conjugative CTs are driven by conjugative elements, bringing into the spotlight a new means for rapid mycoplasma innovation. …”
Publicado 2014
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424por Zhang, Li, Valencia, C Alexander, Dong, Biao, Chen, Meng, Guan, Pu-Jun, Pan, Ling“…This nascent crosstalk model will provide a novel insight into complementing the classic mechanisms of intercellular communication and contribute to the potential therapeutic strategy via small RNA molecule-carrying EMVs for multimodality treatment of cancer.…”
Publicado 2015
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425por de Melo, Fabiana Henriques Machado, Oliveira, Julia Salles, Sartorelli, Viviani Olivastro Bressani, Montor, Wagner Ricardo“…For example, the classic mechanisms may involve activation of free radical scavenging enzymes, control of chronic inflammation, and downregulation of specific signaling pathways. …”
Publicado 2018
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426“…When the expression of GSDME is low, it will lead to the classical mechanism of tumor cell death, which is apoptosis. …”
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427por Murray, Philip R. D., Cox, James H., Chiappini, Nicholas D., Roos, Casey B., McLoughlin, Elizabeth A., Hejna, Benjamin G., Nguyen, Suong T., Ripberger, Hunter H., Ganley, Jacob M., Tsui, Elaine, Shin, Nick Y., Koronkiewicz, Brian, Qiu, Guanqi, Knowles, Robert R.“…As such, MS-PCET can function as a non-classical mechanism for homolytic bond activation, providing opportunities to generate synthetically useful free radical intermediates directly from a wide variety of common organic functional groups. …”
Publicado 2021
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428por Smittarello, D., Smets, B., Barrière, J., Michellier, C., Oth, A., Shreve, T., Grandin, R., Theys, N., Brenot, H., Cayol, V., Allard, P., Caudron, C., Chevrel, O., Darchambeau, F., de Buyl, P., Delhaye, L., Derauw, D., Ganci, G., Geirsson, H., Kamate Kaleghetso, E., Kambale Makundi, J., Kambale Nguomoja, I., Kasereka Mahinda, C., Kervyn, M., Kimanuka Ruriho, C., Le Mével, H., Molendijk, S., Namur, O., Poppe, S., Schmid, M., Subira, J., Wauthier, C., Yalire, M., d’Oreye, N., Kervyn, F., Syavulisembo Muhindo, A.“…Classical mechanisms of volcanic eruptions mostly involve pressure buildup and magma ascent towards the surface(1). …”
Publicado 2022
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429“…In addition to the classical mechanical and neurological origins of LRC, here we demonstrated using the sine circle map model that information plays an important modulatory role of the synchronization, and has global energetic consequences.…”
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430“…Epigenetics refers to heritable mechanisms able to modulate gene expression that do not involve alteration of the genomic DNA sequence. Classically, mechanisms such as DNA methylation and histone modifications were part of this classification. …”
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431por Pirone, Domenico, Bandeira, Nuno A. G., Tylkowski, Bartosz, Boswell, Emily, Labeque, Regine, Garcia Valls, Ricard, Giamberini, Marta“…Both molecules require excitation to the second (S(2)) excited state situated in the visible region to initiate the isomerization. Two classic mechanisms were considered, namely rotation and inversion, with the former being energetically more favorable. …”
Publicado 2020
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432por Quaglia, Marco, Merlotti, Guido, De Andrea, Marco, Borgogna, Cinzia, Cantaluppi, Vincenzo“…In addition to classical mechanisms of viral-triggered autoimmunity, such as molecular mimicry and epitope spreading, there has been a growing appreciation of the role of direct activation of innate response by viral nucleic acids and epigenetic modulation of interferon-related immune response. …”
Publicado 2021
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433“…In this review, we discuss the classic mechanisms as well as novel mechanisms of MGE transfers in the rhizosphere. …”
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434“…Useful for both advanced and early breast cancers, trastuzumab has multiple mechanisms of action. Classical mechanisms attributed to trastuzumab action include cell cycle arrest, induction of apoptosis, and antibody-dependent cell-mediated cytotoxicity (ADCC). …”
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435“…In contrast with this classical mechanical case, the foliations considered in this paper have singularities: all their leaves have a non-empty intersection, they contain limit cycles on their boundaries. …”
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436por Wagner, David H.“…What is surprising, however, is that classic mechanisms of tolerance cannot explain diabetogenesis; alternate mechanisms must now be considered. …”
Publicado 2017
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437por Fiorelli, Lucas E., Martinelli, Agustín G., da Silva, João Ismael, Hechenleitner, E. Martín, Soares, Marcus Vinícius Theodoro, Silva Junior, Julian C. G., da Silva, José Carlos, Borges, Élbia Messias Roteli, Ribeiro, Luiz Carlos Borges, Marconato, André, Basilici, Giorgio, da Silva Marinho, Thiago“…Several egg-clutches, partially preserved, isolated eggs and many eggshell fragments were discovered in an Inceptisol palaeosol profile of the mining Lafarge Quarry, at the Ponte Alta District (Uberaba Municipality, Minas Gerais State), corresponding to the Serra da Galga Formation (Bauru Group, Bauru Basin). Although classical mechanical preparation and CT scans have not revealed embryonic remains in ovo, the eggs and eggshell features match those eggs containing titanosaurian embryos found worldwide. …”
Publicado 2022
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438por Schmutzler, Cornelia, Gotthardt, Inka, Hofmann, Peter J., Radovic, Branislav, Kovacs, Gabor, Stemmler, Luise, Nobis, Inga, Bacinski, Anja, Mentrup, Birgit, Ambrugger, Petra, Grüters, Annette, Malendowicz, Ludwik K., Christoffel, Julie, Jarry, Hubertus, Seidlovà-Wuttke, Dana, Wuttke, Wolfgang, Köhrle, Josef“…CONCLUSIONS: As the effects of EDCs do not reflect classic mechanisms of hormone-dependent regulation and feedback, we believe multitarget and multimodal actions of EDCs affect the hypothalamic–pituitary–thyroid axis. …”
Publicado 2007
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439por Kim, Beomkyu, Eggel, Alexander, Tarchevskaya, Svetlana S., Vogel, Monique, Prinz, Heino, Jardetzky, Theodore S.“…IgE-Fc conformational flexibility indicated that inhibition could be mediated by allosteric or other non-classical mechanisms(6–8). Here we demonstrate that an engineered protein inhibitor, DARPin E2_79(9–11), acts through a non-classical inhibition mechanism, not only blocking IgE:FcεRI interactions, but actively stimulating the dissociation of preformed ligand-receptor complexes. …”
Publicado 2012
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440“…Contrary to the classic mechanism of LysR regulation, PA2206 did not autoregulate its own expression and did not influence expression of adjacent or divergently transcribed genes. …”
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