“…The answer to this question would not only reveal the extent to which we may determine our own conscious visual experience, but also advance our understanding of the neural mechanisms underlying binocular rivalry. Classic studies, intriguingly, reached contradictory conclusions, ranging from an absence of attentional control, as advocated by Breese, to nearly complete control of rivalry dynamics, as reported by Helmholtz. …”
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“…[Image: see text] Isoniazid (INH) is associated with serious liver injury and autoimmunity. Classic studies in rats indicated that a reactive metabolite of acetylhydrazine is responsible for the covalent binding and toxicity of INH. …”
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“…GABAergic granule cells, the most numerous interneuron subtype in this brain region, have been extensively studied. However, classic studies using Golgi staining methods identified many other, nongranule cell types in the OB whose function remains mysterious. …”
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“…In the case of cancer development, multiple genetic changes happen in somatic diploid cells. Most classic studies of the molecular mechanisms of mutagenesis have been performed in haploids. …”
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“…BACKGROUND: In the third molar surgery, it is important to focus not only on surgical skills, but also on patient satisfaction. Classically studies have been focused on surgery and surgeon’s empathy, but there are non-surgical factors that may influence patient satisfaction. …”
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“…There have been few recent studies involving penetrating craniocerebral injuries, and most studies have been restricted to small numbers of patients; classic studies in military and civil environment have identified that this is a highly lethal or devastating violent condition, able to leave marked consequences for the affected individual, the family and the health system itself. …”
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“…Priming and activation of these intracellular protein platforms trigger the maturation of pro-inflammatory chemokines and cytokines, most notably, interleukin-1β (IL-1β) and IL-18, to promulgate innate immune defenses. Although classically studied in models of gout, Type II diabetes, Alzheimer’s disease, and multiple sclerosis, the importance and mechanisms of action of inflammasome priming and activation have recently been elucidated in cells of the respiratory tract where they modulate the responses to a number of inhaled pathogenic particles and fibres. …”
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“…METHODS: A search for papers addressing autonomic related-structures affected by Alzheimer’s degeneration, and under normal condition was performed through MedLine, PsycInfo and Lilacs, on the bibliographical references of papers of interest, together with a manual search for classic studies in older journals and books, spanning over a century of publications. …”
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“…Moreover, it has been suggested that the chronically lipid overloaded heart augments fatty acid oxidation and triglyceride synthesis to an even greater degree and, thus, develops a lipotoxic phenotype. In comparison, classic studies in exercise physiology have provided a basis for the acute metabolic changes that occur during physical activity. …”
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“…This adaptation process, called auditory sensory gating (ASG), is altered in various psychiatric diseases including schizophrenia and is classically studied by focusing on early evoked cortical responses to the second tone (T2) using 500-ms ISI. …”
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“…Conclusions: This analysis provides a better understanding on dyslexia and may help doctors, researchers, and stakeholders to achieve a more comprehensive understanding of classic studies, new discoveries, and trends regarding this research field, thus promoting ideas for future investigation.…”
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“…Therefore, examination of additional neurocircuitries not classically studied in the context of AUD may provide novel therapeutic targets. …”
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“…Adjuvant chemotherapy was superior to surgery alone based on OS and disease free survival (CLASSIC study HR = 0.72, CI: 0.52–1 and HR = 0.56, CI: 0.44–0.72, respectively). …”
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“…Human cancer research in general requires refined models to bridge the gap between basic science research and meaningful clinical trials. Classic studies in cultured cancer cell lines and animal models such as mice and rats often present caveats when extended to humans due to inherent genetic and physiological differences. …”
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“…We propose a novel framework supporting enhanced late-life reappraisal via hippocampal dedifferentiation of memory representations across current and past experiences. We review classic studies supporting mood benefits from integrated positive narratives following adverse autobiographical events. …”
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“…Each trial also contained “wolf” objects, whose movement was inspired by classic studies of multiple object tracking. When participants needed to physically avoid the wolves, foraging patterns changed, with an increased tendency to switch between target categories and a decreased ability to prioritise high reward targets, relative to participants who could safely ignore them. …”
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“…Both types of valid cues reduced reaction time (by 58 and 60 ms, respectively, with no significant difference between them, a larger effect than in many classic studies). In addition, observers’ ability to accurately localize hazards dropped 11% in the spatiotemporal invalid condition, a result with dangerous implications on the road. …”
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“…These findings were not unlike those of classic studies reported from Ponseti’s institution. We conclude that the Ponseti method is not only a technique to achieve initial correction of an idiopathic clubfoot, but also how to manage relapses that will inevitably occur in many patients. …”
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“…This finding links classic studies in plant ecology and prior research in plant physiological ecology to current trait‐based approaches in community ecology. …”
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“…Abstract. Classic studies have successfully linked single-species abundances, life-history traits, assemblage structures and biomass of carabid beetles to past and present, human-caused environmental impacts and variation in ‘natural’ conditions. …”
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