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38561por Johnson, Melissa, Dudek, Arkadiusz Z., Sukari, Ammar, Call, Justin, Kunk, Paul R., Lewis, Karl, Gainor, Justin F., Sarantopoulos, John, Lee, Patrice, Golden, Adele, Harney, Allison, Rothenberg, S. Michael, Zhang, Yuanyuan, Goldman, Jonathan W.“…PURPOSE: ARRY-382 (PF-07265804) is a selective inhibitor of colony-stimulating factor-1 receptor. We evaluated the safety and preliminary efficacy of ARRY-382 plus pembrolizumab in patients with advanced solid tumors. …”
Publicado 2022
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38562“…Imprints were incubated at 37°C under aerobic conditions, and colony-forming units (CFU) on each plate were counted after 24, 48, and 72 h. …”
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38563Effects of Boric Acid Gel on Vaginal Candida albicans Infections and the Local Immune System in Micepor Guo, Xiaoyu, Jing, Tingting, Li, Xiaojing, Liu, Zhao, Chen, Yongxue, Li, Yiquan, Xu, Yanyan, Gao, Hongqi“…In groups B and F, there was less vaginal injury and less exudate, with group B doing better than group F. The numbers of CA colonies were higher in groups B, F, and M than in group N (P < 0.01). …”
Publicado 2022
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38564por Lin, Guizhen, Zhang, Lei, Yan, Zheng, Jiang, Wei, Wu, Beibei, Li, Dongsheng, Xiong, Xiaofang“…Compared with Th17 cells, Th17.1 cells plus transitional Th17.1 cells induced higher expression of C-X-C motif chemokine ligand 1 (CXCL1), C-C motif chemokine ligand 2 (CCL2), C-X-C motif chemokine 5 (CXCL5), and granulocyte-macrophage colony-stimulating factor (GM-CSF) in aortic endothelial cells. …”
Publicado 2022
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38565por Ingalagi, Preeti, Bhat, Kishore G, Kulkarni, R. D., Kotrashetti, Vijayalakshmi S., Kumbar, Vijay, Kugaji, Manohar“…Phenotypical identification was done morphologically and biochemically further quantification of P. gingivalis was done by colony-forming unit. The second aliquot was subjected for DNA extraction and real-time PCR was conducted to detect and quantify P. gingivalis using specific primer. …”
Publicado 2022
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38566por Grace, Alicia, Murphy, Robert, Dillon, Aoife, Smith, Diarmuid, Cryan, Sally-Ann, Heise, Andreas, Fitzgerald-Hughes, Deirdre“…Results: All PLLs, including the linear polypeptide, were bactericidal at 1μM against S. aureus 25923 and P. aeruginosa PAO1, with log reduction in colony forming units/ml between 2.7-3.6. PLL (160 )demonstrated similar killing potency against 20 S. aureus and five P. aeruginosa clinical isolates from DFW, mean log reductions: 3.04 ± 0.16 and 3.96 ± 0.82 respectively after 1 hour incubation. …”
Publicado 2022
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38567“…We found that treatment with IL-36γ increased the proliferation and colony formation of JB6 Cl41 and MCF7 cells. Analysis of the mechanism underlying the neoplastic cell transformation revealed that IL-36γ induced IL-36R-mediated phosphorylation of MEK1/2, ERK1/2, JNK1/2, and c-Jun, resulting in increased c-Fos, c-Jun, and AP-1 activities in JB6 Cl41 and MCF7 cells. …”
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38568por Ng, Lui, Wan, Timothy Ming-Hun, Iyer, Deepak Narayanan, Huang, Zheng, Sin, Ryan Wai-Yan, Man, Abraham Tak-Ka, Li, Xue, Foo, Dominic Chi-Chung, Lo, Oswens Siu-Hung, Law, Wai-Lun“…Overexpression of miR-187-3p in CRC cell lines impaired colony formation, cell migration, and invasion, and induced chemosensitivity. …”
Publicado 2022
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38569por Knecht, Leandra E., Born, Yannick, Pelludat, Cosima, Pothier, Joël F., Smits, Theo H. M., Loessner, Martin J., Fieseler, Lars“…When wild type bacteria were incubated with Y2, permanently resistant colonies (1430(Y2R)) formed spontaneously. In addition, 1430(Y2R) revealed cross-resistance against other phages (Bue1) or lowered the efficiency of plating (L1, S2, and S6). …”
Publicado 2022
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38570por Sohrabi, Maryam, Alizade Naini, Mahvash, Rasekhi, Alireza, Oloomi, Mana, Moradhaseli, Farzad, Ayoub, Abbas, Bazargani, Abdollah, Hashemizadeh, Zahra, Shahcheraghi, Fereshteh, Badmasti, Farzad“…In Galleria mellonella, a concentration of 10(6) colony-forming units of the K1 hvKp strain resulted in 100% death at 24 hours, confirming the higher virulence of the hvKp strain compared with cKp. …”
Publicado 2022
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38571por Del Bufalo, Donatella, Di Martile, Marta, Valentini, Elisabetta, Manni, Isabella, Masi, Ilenia, D’Amore, Antonella, Filippini, Antonio, Nicoletti, Carmine, Zaccarini, Marco, Cota, Carlo, Castro, Maria Victoria, Quezada, María Josefina, Rosanò, Laura, Lopez-Bergami, Pablo, D’Aguanno, Simona“…RESULTS: Results demonstrated that Bcl2L10 acts as an inducer of in vitro cell migration, invasion, and VM, while in vitro cell proliferation, in vivo tumor growth, as well as colony formation properties were not affected. Dissecting different signaling pathways, it was found that Bcl2L10 positively affects the phosphorylation of extracellular-signal-regulated kinase (ERK) and the expression of markers of cell invasion, such as urokinase plasminogen activator receptor (uPAR) and matrix metalloproteinases (MMPs). …”
Publicado 2022
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38572“…METHODS: The cytotoxic effect of Pro A on PC cells was determined using cell viability assay, colony formation assay and transwell assay in vitro. …”
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38573por Markin, Sergey S., Lapshin, Roman D., Baskina, Olga S., Korotchenko, Svetlana A., Mukhina, Irina V., Ivanov, Sergei V., Semenov, Mikhail P., Beregovykh, Valerii V., Semenov, Andrey M.“…Nebulized nSta had a normalizing effect on the proinflammatory cytokines in blood— interleukin (IL)-1α, IL-17A, IL-6, and granulocyte-macrophage colony-stimulating factor (GM-CSF). These data showed the effectiveness of nebulized nSta and the perspectives of its clinical usage in COVID-19 patients with acute respiratory distress syndrome (ARDS).…”
Publicado 2022
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38574por Campanati, Anna, Orciani, Monia, Marani, Andrea, Di Vincenzo, Mariangela, Magi, Simona, Gregoriou, Stamatios, Diotallevi, Federico, Martina, Emanuela, Radi, Giulia, Offidani, Annamaria“…C- and AD-MSCs (T0, T16) were isolated from skin specimens and characterized; the expression/secretion of IL4 and IL13 was evaluated using immuno-cytochemistry (ICC), indirect immune-fluorescence (IIF) and an ELISA test; secretion of IL2, IL4, IL5, IL6, IL10, IL12, IL13, IL17A, Interferon gamma (IFNγ), Tumor necrosis factor alpha (TNFα), Granulocyte Colony-Stimulating Factor (G-CSF), and Transforming Growth Factor beta1 (TGFβ1) were measured with ELISA. …”
Publicado 2022
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38575“…No study has evaluated the effect of therapeutic granulocyte colony-stimulating factor (G-CSF) in preventing recurrence of febrile neutropenia (FN) and survival outcomes in gynecologic cancer patients. …”
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38576por Ti, Gang, Guo, Zongliang, Li, Lili, Lv, Yongqiang, Yang, Bin, Wang, Jian, Guo, Rui, Chen, Yunqing, Meng, Debin, Li, Feng“…Overexpression of miR-33a-5p in BGC-823 and MGC-803 cells greatly inhibited the cell invasion and colony number. Furthermore, compared to sh-control (shControl), RAP2A knockdown (sh-RAP2A/shRAP2A) raised the sensitivity of GC cells to 5-FU significantly, characterized as reducing cell apoptosis. …”
Publicado 2022
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38577“…CP9 significantly attenuated ETEC-induced inflammatory response by reducing ETEC-induced nitric oxide production and relative mRNA expression of the Toll-like receptors (TLRs; TLR2, TLR4, and TLR9), proinflammatory tumor necrosis factor alpha, interleukins (ILs; IL-6 and IL-8), augmenting anti-inflammatory granulocyte-macrophage colony-stimulating factor and host defense peptide mucin 1 (MUC1) mRNA levels. …”
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38578“…Units were then analyzed at various time points up to 96 hours using traditional iShage and colony-forming assays, in parallel with the IL-3-based potency assay. …”
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38579por Loftus, Michael J., Young-Sharma, Tracey E.M.W., Lee, Sue J., Wati, Shitanjni, Badoordeen, Gnei Z., Blakeway, Luke V., Byers, Sally M.H., Cheng, Allen C., Cooper, Ben S., Cottingham, Hugh, Jenney, Adam W.J., Hawkey, Jane, Macesic, Nenad, Naidu, Ravi, Prasad, Amitesh, Prasad, Vinita, Tudravu, Litia, Vakatawa, Timoci, van Gorp, Elke, Wisniewski, Jessica A., Rafai, Eric, Peleg, Anton Y., Stewardson, Andrew J.“…METHODS: We conducted a prospective cohort study of inpatients with Enterobacterales bloodstream infections (BSIs) at Colonial War Memorial Hospital, Suva. We used cause-specific Cox proportional hazards models to estimate the effect of 3GC-R on the daily risk (hazard) of in-hospital mortality and being discharged alive (competing risks), and we used multistate modelling to estimate the excess length of hospital stay. …”
Publicado 2022
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38580por Foray, Claudia, Barca, Cristina, Winkeler, Alexandra, Wagner, Stefan, Hermann, Sven, Schäfers, Michael, Grauer, Oliver M., Zinnhardt, Bastian, Jacobs, Andreas H.“…They can be efficiently targeted by inhibiting the colony-stimulating factor 1 receptor (CSF-1R). We applied noninvasive PET/CT and PET/MRI using (18)F-fluoroethyltyrosine ((18)F-FET) (amino acid metabolism) and N,N-diethyl-2-[4-(2-(18)F-fluoroethoxy)phenyl]-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-acetamide ((18)F-DPA-714) (translocator protein) to understand the role of GAMMs in glioma initiation, monitor in vivo therapy-induced GAMM depletion, and observe GAMM repopulation after drug withdrawal. …”
Publicado 2022
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