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  1. 40301
    “…Co-culture of myeloid-derived suppressor cells (MDSC) with CD8(+) T cells was used to measure immune suppression. Overexpression of colony-stimulating factor-1 (CSF-1) in tumor cells was used to show the effect of tumor-derived CSF-1 on sensitivity to trametinib and anti-programmed death- 1 (αPD-1) in mice. …”
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    MEK1/2 inhibition transiently alters the tumor immune microenvironment to enhance immunotherapy efficacy against head and neck cancer
  2. 40302
    “…Response to fluvastatin was assessed in vitro using the MCF10A cell line model system, including a statin resistant cell line that was generated (MCF10.AT1-R), and measured using colony forming assays. In vivo efficacy of statin for chemoprevention was assessed in the SV40C3 TAg mouse model. …”
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    Gene signature associated with resistance to fluvastatin chemoprevention for breast cancer
  3. 40303
    “…In one case, the mutation arose within the wildtype colony used for expanding mutant lines. CONCLUSIONS: Our data show that spontaneous mutations with observable effects on phenotype are a common side effect of intensive breeding programmes, including those underlying targeted mutation programmes. …”
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    Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme
  4. 40304
    “…INTERVENTIONS: Capsules containing Lactobacillus rhamnosus (HN001) (6×10(9) colony-forming units/day), or placebo capsules; and cereal containing 4 g/day OBG or calorie-matched control cereal, taken daily, for 6 months. …”
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    A randomised controlled trial of a probiotic and a prebiotic examining metabolic and mental health outcomes in adults with pre-diabetes
  5. 40305
    “…The effect of BMI1 on proliferation and migration of OS cells (143B and U-2OS cell lines) was investigated in vitro using CCK-8, colony formation and transwell assays, and in vivo using subcutaneous tumorigenesis and lung metastasis assays in xenograft nude mice. …”
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    BMI1 promotes osteosarcoma proliferation and metastasis by repressing the transcription of SIK1
  6. 40306
    “…Cell proliferation and the cell cycle were assessed by the Cell Counting Kit-8, EDU assay, flow cytometry, colony formation assay, and Western blot analysis. …”
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    NAP1L1 promotes tumor proliferation through HDGF/C-JUN signaling in ovarian cancer
  7. 40307
    “…RESULTS: The UDCs were isolated from swine urine samples and when at passage 2 submitted to in vitro reprogramming. Colonies of putative iPSCs were obtained only from UDCs transduced with the murine factors (mOSKM), but not from human factors (hOSKM). …”
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    In vitro induced pluripotency from urine-derived cells in porcine
  8. 40308
    “…Average liver metastatic colonies’ number per microscope field at the CS-FA-MBZ group (2.3 ± 0.7) was significantly (P < 0.05) lower than the Control (9.6 ± 1.7), MBZ (5.0 ± 1.5), and CS-FA (5.2 ± 1) groups. …”
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    Biodegradable and biocompatible subcutaneous implants consisted of pH-sensitive mebendazole-loaded/folic acid-targeted chitosan nanoparticles for murine triple-negative breast cancer treatment
  9. 40309
    “…RESULTS: Regression analysis demonstrated that LAM was a predictor of colony-forming unit (CFU)/mL values obtained from the 14-day treatment cohort, with well-estimated model parameters (relative standard error ≤ 22.2%). …”
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    Sputum lipoarabinomannan (LAM) as a biomarker to determine sputum mycobacterial load: exploratory and model-based analyses of integrated data from four cohorts
  10. 40310
    “…METHODS: The anti-tumor activity of B28 in PAAD was confirmed by RTCA, colony formation assay and flow cytometry. GO and KEGG enrichment analyses were performed to analyze the differentially expressed genes (DEGs) obtained by RNA sequencing. …”
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    A synthesized olean-28,13β-lactam targets YTHDF1-GLS1 axis to induce ROS-dependent metabolic crisis and cell death in pancreatic adenocarcinoma
  11. 40311
    “…METHODS: We utilized therapy sensitive (MCF7 and ZR75), therapy resistant (MCF7-TamR, MCF7-FR, MCF7-PELP1cyto, MCF7-SETDB1) estrogen receptor alpha positive (ER(+))BC models and conducted in vitro cell viability, colony formation, 3-dimensional cell growth assays to investigate the role of SETDB1 in endocrine resistance. …”
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    SETDB1 interactions with PELP1 contributes to breast cancer endocrine therapy resistance
  12. 40312
    “…In the human study, 120 patients with FC were randomized to treatment [L. plantarum Lp3a; 2×1.0×10(10 )(colony forming units; CFU) ×7 days] or control groups (n=60 each). …”
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    Lactobacillus plantarum Lp3a improves functional constipation: evidence from a human randomized clinical trial and animal model
  13. 40313
    “…Live E. coli, 5 × 10(7) colony-forming units (CFU/mL) was infused in a peripheral vein. …”
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    Evaluation of an extracorporeal ozone-based bactericide system for the treatment of Escherichia coli sepsis
  14. 40314
    “…In our study, the plant diversity in pollen from colonies installed in land-use systems with distinct levels of forest transformation was highly homogeneous, reflecting a large influx of pollen transported by stingless bees through distinct land-use types. …”
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    Biomonitoring via DNA metabarcoding and light microscopy of bee pollen in rainforest transformation landscapes of Sumatra
  15. 40315
    “…Brachial artery flow-mediated dilation (FMD) and endothelial progenitor cell – colony forming units (EPC-CFU) assays were utilized as measures of endothelial function. …”
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    Could COVID-19 Induced Endothelial Dysfunction Explain New Onset Peyronie's Disease?
  16. 40316
    “…Their inhibition effects on cell proliferation and metastasis were firstly compared upon three human NSCLC cell lines in vitro, by cell counting kit-8, colony formation, wound healing and transwell assays respectively. …”
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    Sequence-dependent synergistic effect of aumolertinib-pemetrexed combined therapy on EGFR-mutant non-small-cell lung carcinoma with pre-clinical and clinical evidence
  17. 40317
    “…MATERIALS AND METHODS: CCK8, Edu assays and colony formation assay were performed to assess the effect of SBD on PCa cell growth. …”
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    Scutellaria barbata D.Don (SBD) extracts suppressed tumor growth, metastasis and angiogenesis in Prostate cancer via PI3K/Akt pathway
  18. 40318
    “…METHODS: Anopheles gambiae s.l. eggs obtained from laboratory-established colonies were reared under eight temperature regimes (25, 28, 30, 32, 34, 36, 38, and 40 °C). …”
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    Relationship between temperature and Anopheles gambiae sensu lato mosquitoes' susceptibility to pyrethroids and expression of metabolic enzymes
  19. 40319
    “…In addition, silencing PAFAH1B3 suppressed cell proliferation, colony formation, and invasion and increased the cell population in the G0-G1 phases in vitro. …”
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    PAFAH1B3 predicts poor prognosis and promotes progression in lung adenocarcinoma
  20. 40320
    “…Mice in the CB group received treatment with CB [1×10(8) colony forming unit (CFU) in 100 µL phosphate buffered saline (PBS)] 3 times a week for 40 days by gavage administration. …”
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    Clostridium butyricum inhibits the progression of colorectal cancer and alleviates intestinal inflammation via the myeloid differentiation factor 88 (MyD88)-nuclear factor-kappa B (NF-κB) signaling pathway
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