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40901por Ghosh, Nilanjana, Choudhury, Priyanka, Kaushik, Sandeep Rai, Arya, Rakesh, Nanda, Ranjan, Bhattacharyya, Parthasarathi, Roychowdhury, Sushmita, Banerjee, Rintu, Chaudhury, Koel“…Multiplexed analysis of 25 immunological markers (IFN-γ (interferon gamma), TNF-α (tumor necrosis factor alpha), IL-12p70 (interleukin 12p70), IL-2, IL-4, IL-5, IL-13, IL-10, IL-1α, IL-1β, TGF-β (transforming growth factor), IL-6, IL-17E, IL-21, IL-23, eotaxin, GM-CSF (granulocyte macrophage-colony stimulating factor), IFN-α (interferon alpha), IL-18, NGAL (neutrophil gelatinase-associated lipocalin), periostin, TSLP (thymic stromal lymphopoietin), MCP-1 (monocyte chemoattractant protein- 1), YKL-40 (chitinase 3 like 1) and IL-8) was also performed in the discovery cohort. …”
Publicado 2020
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40902Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCε pathway in a rat model of neonatal HIEpor Hu, Xiao, Li, Shirong, Doycheva, Desislava Met, Huang, Lei, Lenahan, Cameron, Liu, Rui, Huang, Juan, Xie, Shucai, Tang, Jiping, Zuo, Gang, Zhang, John H.“…Neuroinflammation plays an important role in the pathogenesis of HIE, in which microglia are key cellular mediators in the regulation of neuroinflammatory processes. Colony-stimulating factor 1 (CSF1), a specific endogenous ligand of CSF1 receptor (CSF1R), is crucial in microglial growth, differentiation, and proliferation. …”
Publicado 2020
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40903por Wang, Wen-Tao, Chen, Tian-Qi, Zeng, Zhan-Cheng, Pan, Qi, Huang, Wei, Han, Cai, Fang, Ke, Sun, Lin-Yu, Yang, Qian-Qian, Wang, Dan, Luo, Xue-Qun, Sun, Yu-Meng, Chen, Yue-Qin“…LAMP5-AS1 suppression significantly reduced colony formation and increased differentiation of primary MLL leukemia CD34+ cells. …”
Publicado 2020
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40904por Najmuddin, Syed Umar Faruq Syed, Amin, Zahiah Mohamed, Tan, Sheau Wei, Yeap, Swee Keong, Kalyanasundram, Jeevanathan, Ani, Muhamad Alhapis Che, Veerakumarasivam, Abhimanyu, Chan, Soon Choy, Chia, Suet Lin, Yusoff, Khatijah, Alitheen, Noorjahan Banu“…In addressing this issue, genetic/molecular engineering approach has paved its way to improve the therapeutic efficacy as observed in the case of herpes simplex virus (HSV) expressing granulocyte–macrophage colony-stimulating factor (GM-CSF). This study aimed to explore the cytotoxicity effects of recombinant NDV strain AF2240-i expressing interleukin-12 (rAF-IL12) against CT26 colon cancer cells. …”
Publicado 2020
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40905“…This study aimed to observe the efficacy of HLA-mismatched granulocyte colony-stimulating factor (G-CSF)-mobilized peripheral blood stem cells (GPBSCs) infusion for refractory EBV-HLH. …”
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40906“…Cell growth was evaluated by CCK-8 assay, trypan blue staining assay and colony formation assay. The Annexin V-FITC/PI double staining method was employed to measure cell apoptosis ratio. …”
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40907por Matsuyama, Hideyasu, Matsubara, Nobuaki, Kazama, Hirotaka, Seto, Takeshi, Tsukube, Shoko, Suzuki, Kazuhiro“…CONCLUSIONS: Clinicians should consider the patient’s risk of clinically significant ADRs and prophylactic granulocyte colony stimulating factor when selecting the starting dose of cabazitaxel for CRPC. …”
Publicado 2020
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40908por De Luca, Giacomo, Cavalli, Giulio, Campochiaro, Corrado, Della-Torre, Emanuel, Angelillo, Piera, Tomelleri, Alessandro, Boffini, Nicola, Tentori, Stefano, Mette, Francesca, Farina, Nicola, Rovere-Querini, Patrizia, Ruggeri, Annalisa, D'Aliberti, Teresa, Scarpellini, Paolo, Landoni, Giovanni, De Cobelli, Francesco, Paolini, John F, Zangrillo, Alberto, Tresoldi, Moreno, Trapnell, Bruce C, Ciceri, Fabio, Dagna, Lorenzo“…We aimed to examine whether mavrilimumab, an anti-granulocyte–macrophage colony-stimulating factor receptor-α monoclonal antibody, added to standard management, improves clinical outcomes in patients with COVID-19 pneumonia and systemic hyperinflammation. …”
Publicado 2020
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40909por Tang, Xiu-Feng, Ma, Zi-Tong, Gao, Ying-Ying, Wang, Han, Li, Xiao-Xi, Yu, Ping, Liu, Ren-Hui“…The bone mRNA and protein expression of osteoprotegerin (OPG), nuclear factor-kappa B ligand (RANKL), macrophage colony-stimulating factor (M-CSF), d2 isoform of vacuolar (H(+)) ATPase (ATP6V0d2), insulin-like growth factor (IGF-1), bone morphogenetic protein-2 (BMP2), M-CSF, Wnt5a, transforming growth factor-β1 (TGF-β1) were detected for evaluating bone metabolism. …”
Publicado 2020
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40910por Sun, Jingyuan, Zhu, Zhenru, Li, Wenwen, Shen, Mengying, Cao, Chuanhui, Sun, Qingcan, Guo, Zeqin, Liu, Li, Wu, Dehua“…The radioresistant role of UBE2T was examined by colony formation assays in vitro and xenograft tumor models in vivo. …”
Publicado 2020
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40911por Li, Jiangfeng, Xie, Haiyun, Ying, Yufan, Chen, Hong, Yan, Huaqing, He, Liujia, Xu, Mingjie, Xu, Xin, Liang, Zhen, Liu, Ben, Wang, Xiao, Zheng, Xiangyi, Xie, Liping“…Endogenous expression silencing of YTHDF2 and METTL3 was established with lentivirus-based shRNA technique. Colony formation, flow cytometry and trans-well assays were performed for cell function identifications. …”
Publicado 2020
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40912por Onyango, Calleb George, Ogonda, Lilian, Guyah, Bernard, Shiluli, Clement, Ganda, Gregory, Orang’o, Omenge Elkanah, Patel, Kirtika“…Evidence from experimental studies have shown potential usefulness of Squamous Cell Carcinoma Antigen (SCC Ag), Macrophage Colony Stimulating Factor (M-CSF), Vascular Endothelial Growth Factor (VEGF), MicroRNA, p16INKa / ki-67, HPV E6/E7/mRNA, and DNA methylation biomarkers in detecting premalignant cervical neoplasia. …”
Publicado 2020
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40913“…In the presence of hWJSCs or hWJSC-CM, the CD34+ cells produced significantly more primitive CFU-GEMM colonies, HoxB4, and HoxA9 gene expression and lower percentages of CD34+CXCR4+ cells. …”
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40914por Pierce, Stuart R., Fang, Ziwei, Yin, Yajie, West, Lindsay, Asher, Majdouline, Hao, Tianran, Zhang, Xin, Tucker, Katherine, Staley, Allison, Fan, Yali, Sun, Wenchuan, Moore, Dominic T., Xu, Chang, Tsai, Yi-Hsuan, Parker, Joel, Prabhu, Varun Vijay, Allen, Joshua E., Lee, Douglas, Zhou, Chunxiao, Bae-Jump, Victoria“…METHODS: Cell proliferation was assessed by MTT and colony formation assays. Cell cycle and apoptosis were evaluated by Cellometer. …”
Publicado 2021
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40915por Wang, Liang, Sun, Liankang, Liu, Runkun, Mo, Huanye, Niu, Yongshen, Chen, Tianxiang, Wang, Yufeng, Han, Shaoshan, Tu, Kangsheng, Liu, Qingguang“…The effects of MAPKAPK5-AS1 on tumor growth and metastasis were assessed via in vitro experiments, including MTT, colony formation, EdU, flow cytometry, transwell assays, and nude mice models. …”
Publicado 2021
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40916“…Cell proliferation was detected by using CCK-8 kit and colony formation assay. Cell migration was detected by wound‐healing and transwell migration assay. …”
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40917“…We found that the accessory genome of JNQH-PA57 including several prophages, genomic islands, as well as a PAPI-1 family integrative and conjugative element (ICE), mainly contributed to the larger genome of this strain (6,747,067 bp) compared to other popular P. aeruginosa strains (with an average genome size of 6,445,223 bp) listed in Pseudomonas Genome Database. Colony morphology analysis and biofilm crystal staining assay respectively demonstrated an enhanced alginate production and a thicker biofilm formation capability of JNQH-PA57. …”
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40918por Ding, Chenyu, Yi, Xuehan, Chen, Xiangrong, Wu, Zanyi, You, Honghai, Chen, Xiaoyong, Zhang, Gaoqi, Sun, Yong, Bu, Xingyao, Wu, Xiyue, Lin, Zhangya, Gu, Jianjun, Lin, Yuanxiang, Kang, Dezhi“…The half maximal inhibitory concentration (IC50) of TMZ, cell proliferation, apoptosis, migration and invasion were analyzed via Cell Counting Kit-8, colony formation, flow cytometry, wound healing and transwell assays. …”
Publicado 2021
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40919por Zhou, Zhi-hang, Liang, Si-yuan, Zhao, Tong-chao, Chen, Xu-zhuo, Cao, Xian-kun, Qi, Ming, Huang, Ying-ying, Ju, Wu-tong, Yang, Meng, Zhu, Dong-wang, Pang, Yi-chuan, Zhong, Lai-ping“…In vitro experiments showed that compared with the control group, the proliferation, colony formation and migration ability of CAL27 and SCC7 cells were significantly reduced in H-MnO(2)-PEG/TP group, while cell apoptosis was enhanced, and the expression of hypoxia-inducible factor-1α(HIF-1α) was down-regulated. …”
Publicado 2021
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40920por Jiao, Xinyan, Wang, Bo, Feng, Chen, Song, Shaoran, Tian, Bixia, Zhou, Can, Gao, Xiaoqian, Sun, Wei, Liu, Peijun“…The CCK8, MTT, cell counting, colony formation, and 5-ethynyl-2-deoxyuridine (EdU) incorporation assays were used to detect cell proliferation, respectively. …”
Publicado 2021
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