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201“…Following internalization, all three proteins are recruited to the internalized bacteria, however upon generation of actin-rich comet tails, we observed spectrin recruitment to those structures in the absence of adducin or p4.1. …”
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202por Struck, Daniel, Lawyer, Glenn, Ternes, Anne-Marie, Schmit, Jean-Claude, Bercoff, Danielle Perez“…COMET is free to use via an online interface.…”
Publicado 2014
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203por Imanikia, Soudabeh, Galea, Francesca, Nagy, Eszter, Phillips, David H., Stürzenbaum, Stephen R., Arlt, Volker M.“…Induction of comets by BaP was concentration-dependent up to 20 μM; comet% tail DNA was ∼30% at 20 μM BaP and ∼10% in controls. …”
Publicado 2016
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204“…PURPOSE: The aim of this study was to evaluate whether the comet tail artifact on ultrasonography can be used to reliably diagnose benign gallbladder diseases. …”
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205por Schmeiser, Heinz H, Muehlbauer, Karl-Rudolf, Mier, Walter, Baranski, Ann-Christin, Neels, Oliver, Dimitrakopoulou-Strauss, Antonia, Schmezer, Peter, Kratochwil, Clemens, Bruchertseifer, Frank, Morgenstern, Alfred, Kopka, Klaus“…Radiopharmaceuticals used for diagnosis or therapy induce DNA strand breaks, which may be detectable by single-cell gel electrophoresis (called comet assay). Blood was taken from patients before and at different time points after treatment with radiopharmaceuticals; blood cells were investigated by the comet assay using the percentage of DNA in the tail as the critical parameter. …”
Publicado 2019
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206por Lok, Tsun Ming, Wang, Yang, Xu, Wendy Kaichun, Xie, Siwei, Ma, Hoi Tang, Poon, Randy Y. C.“…A further level of control of the timing of mitotic slippage is through p31(comet)-mediated suppression of MAD2 activation. The loss of kinetochore MAD2 was dependent on APC/C(CDC20), indicating a feedback control of APC/C to SAC during prolonged mitotic arrest. …”
Publicado 2020
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207“…The comet assay is a versatile, simple, and sensitive gel electrophoresis–based method that can be used to measure and accurately quantify DNA damage, particularly single and double DNA strand breaks, in single cells. …”
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208“…Here, we show that the ORD signature could be detected in comets by using ultraviolet spectropolarimetric observations conducted at middle size space observatories. …”
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209por Muruzabal, Damián, Sanz-Serrano, Julen, Sauvaigo, Sylvie, Treillard, Bertrand, Olsen, Ann-Karin, López de Cerain, Adela, Vettorazzi, Ariane, Azqueta, Amaya“…Different mechanistic assays are available, such as the comet assay, which detects DNA damage at the level of individual cells. …”
Publicado 2021
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210por Xiong, Aoli, Kaushal, Simran, Tay, Ian Junjie, Engelward, Bevin P., Han, Jongyoon, Preiser, Peter R.“…The CometChip was previously developed using mammalian cells as a high-throughput version of the comet assay. …”
Publicado 2021
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211por Cardoso, Renato, Dusinska, Maria, Collins, Andrew, Manjanatha, Mugimane, Pfuhler, Stefan, Registre, Marilyn, Elespuru, Rosalie“…The in vivo Comet assay measures the generation of DNA strand breaks under conditions in which the DNA will unwind and migrate to the anode in an electrophoresis assay, producing comet-like figures. …”
Publicado 2022
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213por Tutty, Melissa Anne, Vella, Gabriele, Vennemann, Antje, Wiemann, Martin, Prina-Mello, Adriele“…We have found through our interlaboratory comparison that the alkaline comet assay can be suitably applied to the pre-clinical assessment of NBMs, as a reproducible and repeatable methodology for assessing NBM-induced DNA damage. …”
Publicado 2022
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214por Owiti, Norah A., Kaushal, Simran, Martin, Lincoln, Sly, Jamie, Swartz, Carol D., Fowler, Jasmine, Corrigan, Joshua J., Recio, Les, Engelward, Bevin P.“…To address some of these concerns, we have developed the “HepaCometChip” (a.k.a. the HepaRG CometChip), wherein metabolically competent cells are incorporated into a higher throughput CometChip platform. …”
Publicado 2022
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216por Scheeres, Daniel J“…He shows how it is possible to model the small body environment, including specialised cases such as those of binary asteroids, comets and ‘rubble piles’, and how the fundamental equations of motion are derived. …”
Publicado 2012
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218por Cooper, Christian R., Jones, Donald J. L., Jones, George D. D., Petersson, Kristoffer“…Therefore, the aim of the current study was to profile FLASH-induced damage via the Comet assay, assessing any DNA crosslink formation as a putative marker of RRR and/or anoxic DNA damage formation as an indicative marker of TOD, to determine the extent to which either mechanism contributes to the “FLASH effect”. …”
Publicado 2023
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219por Willits, I, Price, L, Parry, A, Tilby, M J, Ford, D, Cholerton, S, Pearson, A D J, Boddy, A V“…DNA damage was measured using the alkaline COMET assay, and quantified as the percentage of highly damaged cells per sample. …”
Publicado 2005
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220por McGlynn, A P, Wasson, G R, O'Reilly, S, McKelvey-Martin, V J, McNulty, H, Strain, J J, McKerr, G, Mullan, F, Mahmud, N, Scott, J, Weir, D G, Downes, C S“…The alkaline single-cell gel electrophoresis or comet assay is a relatively simple method of measuring DNA single-strand breaks and alkali-labile sites in individual cells. …”
Publicado 2003
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