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281por Moore, Wendy C., Kornmann, Oliver, Humbert, Marc, Poirier, Claude, Bel, Elisabeth H., Kaneko, Norihiro, Smith, Steven G., Martin, Neil, Gilson, Martyn J., Price, Robert G., Bradford, Eric S., Liu, Mark C.“…Here, we examine the clinical impact of stopping mepolizumab after long-term use. METHODS: COMET (NCT02555371) was a randomised, double-blind, placebo-controlled, parallel-group, multicentre study. …”
Publicado 2022
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282por Copp, Michaela E., Chubinskaya, Susan, Bracey, Daniel N., Shine, Jacqueline, Sessions, Garrett, Loeser, Richard F., Diekman, Brian O.“…Chondrocytes from younger donors (<45 years) had less DNA damage than older donors (>70 years) as assessed by the percentage of DNA in the comet “tail”. In donors between 50 and 60 years old, there was increased DNA damage in chondrocytes from OA cartilage as compared to cadaveric. …”
Publicado 2022
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285por Bennett, Sophia Elizabeth“…Monsieur Henri-Michel Comet Préfet de la région Auvergne-Rhône-Alpes République française…”
Publicado 2017
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286por Wellbrock, A., Jones, G. H., Dresing, N., Coates, A. J., Simon Wedlund, C., Nilsson, H., Sanchez‐Cano, B., Palmerio, E., Turc, L., Myllys, M., Henri, P., Goetz, C., Witasse, O., Nordheim, T. A., Mandt, K.“…We analyze observations of a solar energetic particle (SEP) event at Rosetta's target comet 67P/Churyumov‐Gerasimenko during 6–10 March 2015. …”
Publicado 2022
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287por Duty, Susan M, Singh, Narendra P, Silva, Manori J, Barr, Dana B, Brock, John W, Ryan, Louise, Herrick, Robert F, Christiani, David C, Hauser, Russ“…VisComet image analysis software was used to measure comet extent, a measure of total comet length (micrometers); percent DNA in tail (tail%), a measure of the proportion of total DNA present in the comet tail; and tail distributed moment (TDM), an integrated measure of length and intensity (micrometers). …”
Publicado 2003
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288“…In this study, we show that although pure cofilin can disassemble Listeria monocytogenes actin comet tails, it cannot efficiently disassemble comet tails in the presence of polymerizable actin. …”
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289“…The comet assay was used to estimate radiobiological hypoxic fraction across a full range of tumour oxygenations in C3H mammary tumours implanted into the feet of female CDF1 mice. …”
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290por Lisowska, Halina, Deperas-Kaminska, Marta, Haghdoost, Siamak, Parmryd, Ingela, Wojcik, Andrzej“…The present investigation was carried out to test this. Using the alkaline comet assay we analysed the level of DNA damage and repair in isolated γδ T-lymphocytes, pan T-lymphocytes and in total PBMC exposed in vitro to gamma radiation. …”
Publicado 2010
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294“…The comet assay is a simple and cost effective technique, commonly used to analyze and quantify DNA damage in individual cells. …”
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295por Apostolou, Panagiotis, Toloudi, Maria, Kourtidou, Eleni, Mimikakou, Georgia, Vlachou, Ioanna, Chatziioannou, Marina, Papasotiriou, Ioannis“…Single Cell Gel lectrophoresis - also known as a comet assay - is used to detect DNA damage at the level of individual eukaryotic cells. …”
Publicado 2014
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296“…However, this rapidly emerging field lacks dedicated visualisation tools that can display features specific to epigenetic datasets. RESULT: We developed coMET, an R package and online tool for visualisation of EWAS results in a genomic region of interest. coMET generates a regional plot of epigenetic-phenotype association results and the estimated DNA methylation correlation between CpG sites (co-methylation), with further options to visualise genomic annotations based on ENCODE data, gene tracks, reference CpG-sites, and user-defined features. …”
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297por de Lapuente, Joaquín, Lourenço, Joana, Mendo, Sónia A., Borràs, Miquel, Martins, Marta G., Costa, Pedro M., Pacheco, Mário“…Since Singh and colleagues, in 1988, launched to the scientific community the alkaline Single Cell Gel Electrophoresis (SCGE) protocol, or Comet Assay, its uses and applications has been increasing. …”
Publicado 2015
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299“…The present work was aimed at the evaluation of DNA damage in metal workers by Alkaline Comet Assay in blood lymphocytes. The results showed that there was significant difference statistically between the level of DNA damage in blood lymphocytes of metal workers and control group (p < 0.05). …”
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300por Li, Hong, Li, Yi-Dan, Zhu, Wei-Wei, Kong, Ling-Yun, Ye, Xiao-Guang, Cai, Qi-Zhe, Sun, Lan-Lan, Lu, Xiu-Zhang“…Ultrasound lung comets (ULCs) are a nonionizing bedside approach to assess extravascular lung water. …”
Publicado 2018
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