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401por Cascajosa-Lira, Antonio, Puerto, María, Prieto, Ana I., Pichardo, Silvia, Díez-Quijada Jiménez, Leticia, Baños, Alberto, Guillamón, Enrique, Moyano, Rosario, Molina-Hernández, Verónica, Jos, Ángeles, Cameán, Ana M.“…After oral administration (doses: 5.5, 17.4, and 55.0 mg/kg PTS body weight), a combination of the micronucleus (MN) assay (OECD 474) in bone marrow and the standard and enzyme-modified comet assay (OECD 489) was performed. After necropsy, histopathological studies were also carried out. …”
Publicado 2021
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402por Wang, Yiying, Mittelstaedt, Roberta A., Wynne, Rebecca, Chen, Ying, Cao, Xuefei, Muskhelishvili, Levan, Davis, Kelly, Robison, Timothy W., Sun, Wei, Schmidt, Elizabeth K., Smith, Thomas H., Norgaard, Zachary K., Valentine, Charles C., Yaplee, Jeffry, Williams, Lindsey N., Salk, Jesse J., Heflich, Robert H.“…In the current study, we assayed DNA damage with the high‐throughput CometChip assay and quantified mutagenesis with Duplex Sequencing, an error‐corrected next‐generation sequencing method capable of detecting a single mutation per 10(7) base pairs. …”
Publicado 2021
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405por Miranda-Vilela, Ana L, Alves, Penha CZ, Akimoto, Arthur K, Lordelo, Graciana S, Gonçalves, Carlos A, Grisolia, Cesar K, Klautau-Guimarães, Maria N“…These were induced by exposing leukocytes from peripheral blood of healthy humans (N = 135) to hydrogen peroxide (H(2)O(2)), and the effects were tested by comet assay. Blood samples were submitted to genotyping and comet assay (before and after treatment with H(2)O(2 )at 250 μM and 1 mM). …”
Publicado 2010
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406por Tavakoli, Mohammad, Bateni, Ensiyeh, Rismanchian, Mansour, Fathi, Mohammadhossein, Doostmohammadi, Ali, Rabiei, Azim, Sadeghi, Hojat, Etebari, Mahmood, Mirian, Mina“…MATERIALS AND METHODS: In this in vitro experimental study, periodontal C165 fibroblasts cells were cultured in their logarithmic phase and the genotoxicity of novel synthesized bioactive glass nanoparticles and Novabone bioglass was studied in different concentrations and a control group using Comet assay test. By using Autocomet software, three parameters (Tail length, %DNA in tail, Tail moment) were analyzed; the genotoxicity of mentioned biomaterials and control group. …”
Publicado 2012
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407por LI, JIANGUO, WANG, YAN, DU, LIQING, XU, CHANG, CAO, JIA, WANG, QIN, LIU, QIANG, FAN, FEIYUE“…To identify an effective method of evaluating the radiosensitivity of human tumor cell lines in vitro, the present study adopted mtDNA-4977-bp deletion coupled with comet assay. The three human tumor cell lines applied were HepG(2), EC-9706 and MCF-7. …”
Publicado 2014
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408por Fretland, Åsmund Avdem, Kazaryan, Airazat M, Bjørnbeth, Bjørn Atle, Flatmark, Kjersti, Andersen, Marit Helen, Tønnessen, Tor Inge, Bjørnelv, Gudrun Maria Waaler, Fagerland, Morten Wang, Kristiansen, Ronny, Øyri, Karl, Edwin, Bjørn“…METHODS/DESIGN: The Oslo-CoMet Study is a randomized trial into laparoscopic versus open liver resection for the surgical management of hepatic colorectal metastases. …”
Publicado 2015
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409por Hebert, Amanda, Bishop, Michelle, Bhattacharyya, Dhiman, Gleason, Karen, Torosian, Stephen“…This assay measures toxicity based on the area or intensity of the comet-like shape that DNA fragments produce when DNA damage has occurred. …”
Publicado 2014
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410por Powell, Kingsley, Wilson, Victoria J., Redmond, Niamh M., Gaunt, Daisy M., Ridd, Matthew J.“…We report on the impact of different recruitment strategies used in the Choice of Moisturiser in Eczema Treatment (COMET) study – a feasibility trial comparing the effectiveness of four emollients for the treatment of childhood eczema – recruiting via general practitioner (GP) surgeries. …”
Publicado 2016
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411por Ridd, Matthew J, Garfield, Kirsty, Gaunt, Daisy M, Hollinghurst, Sandra, Redmond, Niamh M, Powell, Kingsley, Wilson, Victoria, Guy, Richard H, Ball, Nicola, Shaw, Lindsay, Purdy, Sarah, Metcalfe, ChrisEnlace del recurso
Publicado 2016
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412“…COMET 3D does scanning of the carburetor body by which COLIN 3D software is used for measurements, editing, and analyzing of the acquired point clouds data. …”
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413por Medrano-Padial, Concepción, Puerto, María, Prieto, Ana Isabel, Ayala, Nahúm, Beaumont, Pauline, Rouger, Caroline, Krisa, Stéphanie, Pichardo, Silvia“…The combination of micronucleus assay in bone marrow (OECD 474) and standard (OECD 489) and enzyme-modified comet assay was used to determine the genotoxicity on cells isolated from stomach, liver, and blood of exposed animals. …”
Publicado 2021
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414por Carrà, Giuseppe, Crocamo, Cristina, Bartoli, Francesco, Riboldi, Ilaria, Sampogna, Gaia, Luciano, Mario, Albert, Umberto, Carmassi, Claudia, Cirulli, Francesca, Dell’Osso, Bernardo, Menculini, Giulia, Nanni, Maria Giulia, Pompili, Maurizio, Sani, Gabriele, Volpe, Umberto, Fiorillo, Andrea“…METHODS: We capitalised on data (N = 17,628) from a large, cross-sectional, national survey, the COMET study, run between March and May 2020. While psychological distress was measured by General Health Questionnaire–12 (GHQ-12), the Depression, Anxiety and Stress Scale-21 Items (DASS-21) was used to assess relevant domains. …”
Publicado 2022
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415“…We found that the comet images became diffused and the viability of the cells decreased substantially (>20%) as the UVA dose and benzo [a] pyrene (BaP) concentration exceeded 6.3 J/cm(2) and 10(−6) mol/L BaP. …”
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416por Blondel, Sylvie“…À l'histoire de ce savant, Sylvie Blondel superpose le récit d'une tranche de vie de notre temps : celle d'un homme qui part à la recherche de ce chasseur de comètes tombé dans l'oubli, ainsi que de sa propre femme qui a quitté la maison un beau jour sans laisser de trace. …”
Publicado 2015
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417por Choi, Sugy, O’Grady, Megan A., Cleland, Charles M., Knopf, Elizabeth, Hong, Sueun, D’Aunno, Thomas, Bao, Yuhua, Ramsey, Kelly S., Neighbors, Charles J.Enlace del recurso
Publicado 2023
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418“…Single-cell electrophoresis (comet assay) has been used to evaluate DNA damage and repair in the human myeloid leukaemia cell line K562 after low-dose (predominantly sub-lethal) treatments of hyperthermia and photodynamic therapy (PDT). …”
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419por Zhao, Jin, Guo, Zhong, Zhang, Hong, Wang, Zhenhua, Song, Lei, Ma, Jianxiu, Pei, Shuyan, Wang, Chenjing“…Substantial amounts of residual damage, assessed by the neutral comet assay, were present after irradiation (p < 0.05). …”
Publicado 2013
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420“…MATERIAL AND METHODS: We investigated the ability of vitamin C to reduce the damage induced by hydrogen peroxide, in human colorectal adenocarcinoma cells in vitro by the comet assay. Additionally, we measured the kinetics and efficacy of the repair of DNA damage after incubation with vitamin C in the presence of H(2)O(2). …”
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