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441por Hwang, E Shelley, Hyslop, Terry, Lynch, Thomas, Frank, Elizabeth, Pinto, Donna, Basila, Desiree, Collyar, Deborah, Bennett, Antonia, Kaplan, Celia, Rosenberg, Shoshana, Thompson, Alastair, Weiss, Anna, Partridge, Ann“…METHODS AND ANALYSIS: COMET is a phase III, randomised controlled clinical trial for patients with low-risk DCIS. …”
Publicado 2019
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442por Kašuba, Vilena, Milić, Mirta, Želježić, Davor, Mladinić, Marin, Pizent, Alica, Kljaković-Gašpić, Zorana, Balija, Melita, Jukić, Irena“…Exposed women had significantly higher comet tail intensity (TI) and length (TL) than control women. …”
Publicado 2020
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443por Siskind, Dan, Russell, Anthony W., Suetani, Shuichi, Flaws, Dylan, Kisely, Steve, Moudgil, Vikas, Northwood, Korinne, Robinson, Gail, Scott, James G., Stedman, Terry, Warren, Nicola, Winckel, Karl, Cosgrove, Peter, Baker, AndreaEnlace del recurso
Publicado 2021
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444por Wang, Shirlene D., Devjani, Shivali, Chillakanti, Mahima, Dunton, Genevieve F., Mason, Tyler B.Enlace del recurso
Publicado 2021
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445por Ji, Shengjun, Hu, Qunchao, Zhu, Jiahao, Chen, Jie, Chen, Qingqing, Liu, Zhengcao, Shen, Chen, Yang, Ru, Sun, Haoyao, Wu, Jinchang, Gu, Ke“…All patients will be randomly divided into four arms to receive either (1) intensity modulated radiation therapy (IMRT), (2) RapidArc, (3) positron emission tomography/computed tomography (PET/CT) with F-18 fluorodeoxyglucose (FDG), or (4) Comet assay-guided IMRT, PET/CT, and Comet assay-guided RapidArc. …”
Publicado 2018
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446por Hu, Jiang, Lloyd, Mel, Hobbs, Cheryl, Cox, Peter, Burke, Keith, Pearce, Gareth, Streicker, Michael A., Gao, Quanyin, Frankos, Vasilios“…Relative total growth at the highest analyzable concentrations at 3 h (±S9) and 24 h (-S9) ranged from 64 to 133 %. In the comet assay, no statistically significant increases in DNA strand breaks were detected in the colon or kidney following oral gavage of 500, 1000 or 2000 mg/kg/day in male F344 rats for 2 days compared to concurrent vehicle control. …”
Publicado 2021
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447por Lokhandwala, Tasneem, Acharya, Mahip, Farrelly, Eileen, Coutinho, Anna D, Bell, Christopher F, Svedsater, Henrik“…Step 2 was the within-trial economic analysis, in which unit costs from Step 1 were applied to the resource use (based on maximum respiratory support and length of stay for inpatient events and number of visits for outpatient events) observed during the first 29 days post-randomization in COMET-ICE. RESULTS: A total of 1,057 patients from the intent-to-treat COMET-ICE population were included (sotrovimab, n = 528; placebo, n = 529). …”
Publicado 2022
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448por Pothmann, Daniela, Simar, Sophie, Schuler, Detlef, Dony, Eva, Gaering, Stéphane, Le Net, Jean-Loïc, Okazaki, Yoshi, Chabagno, Jean Michel, Bessibes, Cécile, Beausoleil, Julien, Nesslany, Fabrice, Régnier, Jean-François“…Twenty-four hours post-exposure, chromosomal aberrations in the bone marrow cells were evaluated by the micronucleus test and DNA damages in the lung, kidney and liver cells by both the standard and the human 8-oxoguanine DNA N-glycosylase 1 (hOGG1)-modified comet assay. All studies were performed according to the OECD test guidelines. …”
Publicado 2015
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449por Siskind, Dan, Friend, Nadia, Russell, Anthony, McGrath, John J, Lim, Carmen, Patterson, Sue, Flaws, Dylan, Stedman, Terry, Moudgil, Vikas, Sardinha, Savio, Suetani, Shuichi, Kisely, Steve, Winckel, Karl, Baker, AndreaEnlace del recurso
Publicado 2018
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450por Åkerlund, Emma, Cappellini, Francesca, Di Bucchianico, Sebastiano, Islam, Shafiqul, Skoglund, Sara, Derr, Remco, Odnevall Wallinder, Inger, Hendriks, Giel, Karlsson, Hanna L., Johnson, G.“…The results showed increased DNA strand breaks (comet assay) for the NiO NPs and at higher doses also for the Ni NPs whereas no effects were observed for Ni ions/complexes from NiCl(2). …”
Publicado 2017
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451por Sablerolles, Roos S. G., Hogenhuis, Freija E. F., Lafeber, Melvin, van de Loo, Bob P. A., Borgsteede, Sander D., Boersma, Eric, Versmissen, Jorie, van der Kuy, Hugo“…The COvid MEdicaTion (COMET) study is an observational, multinational study that focused on the clinical course of COVID‐19 (i.e. hospital mortality and intensive care unit [ICU] admission), and included COVID‐19 patients who were registered at the emergency department or admitted to clinical wards of 63 participating hospitals. …”
Publicado 2021
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452por Juricic, Stefan A., Stojkovic, Sinisa M., Galassi, Alfredo R., Stankovic, Goran R., Orlic, Dejan N., Vukcevic, Vladan D., Milasinovic, Dejan G., Aleksandric, Srdjan B., Tomasevic, Miloje V., Dobric, Milan R., Nedeljkovic, Milan A., Beleslin, Branko D., Dikic, Miodrag P., Banovic, Marko D., Ostojic, Miodrag C., Tesic, Milorad B.“…BACKGROUND: The COMET-CTO trial was a randomized prospective study that assessed long-term follow-up in patients with chronic total occlusion (CTO) in coronary arteries treated with percutaneous coronary intervention (PCI) or with optimal medical therapy (OMT). …”
Publicado 2023
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455“…Comets are considered the most primitive planetary bodies in our Solar System. …”
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456por Kang, Changgeun, Lee, Hyungkyoung, Yoo, Yong-San, Hah, Do-Yun, Kim, Chung Hui, Kim, Euikyung, Kim, Jong Shu“…The toxic effects of ZEN are well known, but the ability of an alkaline Comet assay to assess ZEN-induced oxidative DNA damage in Chang liver cells has not been established. …”
Publicado 2013
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457por Prinsen, Cecilia A C, Vohra, Sunita, Rose, Michael R, King-Jones, Susanne, Ishaque, Sana, Bhaloo, Zafira, Adams, Denise, Terwee, Caroline B“…BACKGROUND: The Core Outcome Measures in Effectiveness Trials (COMET) initiative aims to facilitate the development and application of ‘core outcome sets’ (COS). …”
Publicado 2014
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458por Dhopavkar, Vaidehi Vikas, Shivanand, Sunita S., Bhat, Kishore, Patil, Anand C., Doddwad, Preeti K., Godbole, Niraj Jayant“…Cytotoxicity was assessed by 3,(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and genotoxicity was assessed by Comet assay at time intervals at 24 h and 48 h. STATISTICAL ANALYSIS: Data were analyzed by the Kruskal–Wallis and Mann–Whitney U-test. …”
Publicado 2021
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459por Kühbacher, Andreas, Emmenlauer, Mario, Rämo, Pauli, Kafai, Natasha, Dehio, Christoph, Cossart, Pascale, Pizarro-Cerdá, Javier“…In particular our results show that the requirements for actin nucleators during Listeria entry and actin comet tail formation are different. Knockdown of several actin nucleators, including SPIRE2, reduced bacterial invasion while not affecting the generation of comet tails. …”
Publicado 2015
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460“…The cells were analyzed for DNA strand breakage using the SCGE/COMET assay with mean olive tail moment as a marker of DNA damage. …”
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