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541por Guo, Xuan, Li, Zhou, Yao, Qiuming, Mueller, Ryan S, Eng, Jimmy K, Tabb, David L, Hervey, William Judson, Pan, Chongle“…Benchmarking with soil and marine microbial communities demonstrated a higher number of peptide and protein identifications by Sipros Ensemble than MyriMatch/Percolator, Comet/Percolator, MS-GF+/Percolator, Comet & MyriMatch/iProphet and Comet & MyriMatch & MS-GF+/iProphet. …”
Publicado 2018
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542por Leseigneur, Guillaume, Bredehöft, Jan Hendrik, Gautier, Thomas, Giri, Chaitanya, Krüger, Harald, MacDermott, Alexandra J., Meierhenrich, Uwe J., Caro, Guillermo M. Muñoz, Raulin, François, Steele, Andrew, Steininger, Harald, Szopa, Cyril, Thiemann, Wolfram, Ulamec, Stephan, Goesmann, Fred“…The most pristine material of the Solar System is assumed to be preserved in comets in the form of dust and ice as refractory matter. …”
Publicado 2022
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543“…We also performed an alkali comet assay to detect single-strand breaks (SSB) and alkali labile sites (ALS). …”
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544por Lestari, Mayang Indah, Murti, Krisna, Liberty, Iche Andriyani, Hafy, Zen, Linardi, Violantina, Khoirudin, Muhammad, Umar, Tungki Pratama“…From our meta-analysis, which compared the extent of DNA damage in operating room workers to the unexposed group, operating room workers exposed to WAGs had a significantly higher DNA damage indicator, including DNA damage score, comet tail's length, comet tail's DNA percentage, micronuclei formation, and total chromosomal aberration (p < 0.05) than non-exposed group. …”
Publicado 2023
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545por Reymann, Anne-Cécile, Suarez, Cristian, Guérin, Christophe, Martiel, Jean-Louis, Staiger, Christopher J., Blanchoin, Laurent, Boujemaa-Paterski, Rajaa“…Following its binding to the actin networks, ADF/cofilin is able to break up the dense actin filament array of a comet tail. Stochastic severing by ADF/cofilin loosens the tight entanglement of actin filaments inside the comet tail and facilitates turnover through the macroscopic release of large portions of the aged actin network.…”
Publicado 2011
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546“…The Comet assay and cell cycle analysis were performed 48 hours after the treatment. …”
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547por Davison, Gareth W.“…The alkaline single-cell gel electrophoresis or “comet assay” is a simple and reliable method for measuring the components of DNA stability in eukaryotic cells. …”
Publicado 2016
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548por Dodd, Susanna, Clarke, Mike, Becker, Lorne, Mavergames, Chris, Fish, Rebecca, Williamson, Paula R.“…CONCLUSIONS: This outcome taxonomy will be used to annotate outcomes included in COS within the COMET database and is currently being piloted for use in Cochrane Reviews within the Cochrane Linked Data Project. …”
Publicado 2018
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549por Di Giorgio, M, Bonomi, M, Busto, E, Mairal, L, Menendez, P, Roth, B, Sardi, M, Taja, M R, Vallerga, M B“…One over reactor was also evaluated trough comet assay. DNA damage and repair capacity were quantified by the tail moment. …”
Publicado 2003
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550“…Modified Ames tests and Comet assays have been developed for measuring mutagenicity and genotoxicity. …”
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551por Ryser, Marc D., Greenwald, Matthew A., Sorribes, Inmaculada C., King, Lorraine M., Hall, Allison, Geradts, Joseph, Weaver, Donald L., Mallo, Diego, Holloway, Shannon, Monyak, Daniel, Gumbert, Graham, Vaez-Ghaemi, Shariar, Wu, Ethan, Murgas, Kevin, Grimm, Lars J., Maley, Carlo C., Marks, Jeffrey R., Shibata, Darryl, Hwang, E. Shelley“…Here we show that this pattern of spread is consistent with a new ‘Comet’ model of DCIS tumorigenesis, whereby multiple subclones arise early and nucleate the buds of the growing tumor. …”
Publicado 2023
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552por Rodríguez-Pena, Elba, Suárez, Diego, Estévez-Pérez, Graciela, Verísimo, Patricia, Barreira, Noelia, Fernández, Luis, González-Tizón, Ana, Martínez-Lage, Andrés“…In this work, we analyse the viability and the possible genetic damage in sperm accumulated in the seminal receptacles of M. brachydactyla females as a function of the storage time (from 0 to 14 months) using the comet assay technique. On one hand, we developed an algorithm for comet image analysis that improves the comet segmentation compared with the free software Open comet v1.3.1 (97% vs. 76% of detection). …”
Publicado 2023
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553por Binková, B, Lewtas, J, Mísková, I, Rössner, P, Cerná, M, Mrácková, G, Peterková, K, Mumford, J, Meyer, S, Srám, R“…The GSTM1 genotype had a significant effect on urinary PAH metabolites, urine mutagenicity, and comet parameters (% T and tail moment) when the GSTM1 genotype was considered as a single factor affecting these biomarkers. …”
Publicado 1996
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554“…The CA % is also directly related to exposure. The comet assay findings reveal that the mean comet length and tail length increases with exposure time. …”
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555por Castagna, Olivier, Regnard, Jacques, Gempp, Emmanuel, Louge, Pierre, Brocq, François Xavier, Schmid, Bruno, Desruelle, Anne-Virginie, Crunel, Valentin, Maurin, Adrien, Chopard, Romain, MacIver, David Hunter“…RESULTS: The ultrasound lung comet score was 0 following both the dives at rest regardless of breathing pressure. …”
Publicado 2018
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556por Tugce Yesil, Devecioglu, Aydogan, Fatih, Omurtag, Gulden Zehra, Bese, Nuran Senel, Sardas, Semra“…Peripheral blood lymphocytes were used to measure oxidized DNA damage using formamidopyrimidine DNA-glycosylase (FPG) and endonuclease III (endo III) in a modified comet assay. Individual DNA repair capacity was evaluated with the comet assay after a hydrogen peroxide (H(2)O(2)) challenge to examine the difference in DNA damage susceptibility. …”
Publicado 2018
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557por Alhawmdeh, Maysa, Isreb, Mohammad, Aziz, Abid, Jacob, Badie K., Anderson, Diana, Najafzadeh, Mojgan“…Also, it caused a significant reduction in DNA damage in the lymphocytes from lung cancer patients in both the Comet and micronucleus assays. The 100 U·mL(−1) of IFN-γ liposome significantly reduced the oxidative stress caused by H(2)O(2) and appeared to be effective in both groups using the Comet and micronucleus assays. …”
Publicado 2021
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558por Urazbaev, Arshat, Serikbaeva, Anara, Tvorogova, Anna, Dusenbayev, Azamat, Kauanova, Sholpan, Vorobjev, Ivan“…Parameters of comets (shape, form, and velocity) were used as topological characteristics of 3D voxel objects. …”
Publicado 2021
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559por Bukowski, Karol, Marciniak, Beata, Kciuk, Mateusz, Mojzych, Mariusz, Kontek, Renata“…Cytotoxic and genotoxic properties of the tested compounds were estimated using the MTT assay, comet assay (alkaline and neutral version), and γ-H2AX immuno-staining. …”
Publicado 2022
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560The effects of cysteine and L-carnitine on the DNA integrity of post-thaw sperm of frozen buck semen“…Comet assay revealed significant decreases in DNA damage with best results at 2.5 mM cysteine and 7.5 mM LC. …”
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