“…The results of the enzyme-modified comet assay suggest a DNA oxidative damage induced by nicotine. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In both versions of the comet assay treatment with STC + 5-M-STC, less DNA damage intensity occurred compared to single mycotoxin treatment, suggesting an antagonistic genotoxic action.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After semen analysis, the remaining volume was used for evaluation of three types of sperm DNA damage: (i) total DNA fragmentation, using an alkaline comet assay, (ii) double-stranded DNA fragmentation, using a neutral comet assay, and (iii) oxidative DNA damage, using an alkaline comet assay associated with the DNA glycosylase formamidopyrimidine enzyme. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Further, B. ceiba extract displayed moderate cytotoxicity against Huh7 cells and no cytotoxicity against HepG2 and A549 cells. The comet assay findings showed that Huh7 cells treated with four concentrations of B. ceiba extract (¼ IC(50), ½ IC(50), IC(50), and double IC(50)) increased the comet tail formation within 48 h in a concentration-dependent manner. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After travelling through the Solar System for nearly 10 years Rosetta arrived at its main target, Comet 67/P Churyumov-Gerasimenko, in August 2014. …”
Enlace del recurso

“…In The Carvedilol Or Metoprolol European Trial (COMET) two beta blockers were compared in a double-blind randomized matter. …”
Enlace del recurso
Enlace del recurso

“…Oxidative DNA damage was estimated by nuclear condensation assessment, fluorescence-activated cell sorting analysis, and Comet assay. Rutaecarpine inhibited cell death induced by 500 μM H(2)O(2), as assessed by 4',6-diamidino-2-phenylindole (DAPI) staining. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…DNA damage was detected using the comet assays; the combination led to the highest alkaline- and neutral-comet percentages, demonstrating exacerbation of both single- and double-strand breaks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Thin sections revealed that the net of actin filaments is not formed nor is a "comet" tail produced.…”
Enlace del recurso
Enlace del recurso

“…Data generated from the comet assay also indicated a slight dose-dependent increase in DNA damage in MCF-7 cells associated with VA treatment. …”
Enlace del recurso
Enlace del recurso

“…METHODS: Peripheral blood was used to perform the alkaline and neutral comet assay; and genetic polymorphisms by PCR/RFLP. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Comet scores were calculated as mean ± standard error of mean (SEM) using one-way ANOVA. …”
Enlace del recurso
Enlace del recurso

“…Also, there was a decrease in the level of DNA damage in the comet assay after treating WBCs from healthy individuals, asthma and COPD groups with aspirin N (ASP N) but not with IBU N. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The two occasions could be interchanged. Comet assay was performed on two specimens on the same day for the evaluation of lymphocytic DNA damage with or without oxidative stress. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The aim of this study was to investigate the cytotoxic, genotoxic, mutagenic, and protective effects of 2HMC using the Ames mutagenicity test, the mouse bone marrow micronucleus test, and the comet assay in mice. In the assessment using the Ames test, 2HMC did not increase the number of His(+) revertants in Salmonella typhimurium strains, demonstrating lack of mutagenicity. 2HMC showed no significant increase in micronucleated polychromatic erythrocyte frequency (MNPCE) in the micronucleus test, or in DNA strand breaks using the comet assay, evidencing absence of genotoxicity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…According to our results, for short term exposure, SEM analyses of gills and liver histopathological analyses could be useful tools for the evaluation of target organ damage as well as comet assays for DNA damage. We propose that the 96-h laboratory bioassay protocol described is useful for monitoring the deterioration of water quality employing the teleost C. decemmaculatus and that the microscope analysis of gills and liver as well as the comet assay methodology could be sensitive endpoint indicators.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, some of the studies followed both autologous and allogenic CLET, but described the results together, for both procedures, and therefore it was impossible to analyze them separately. COMET presented some advantages compared to CLET. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Single-cell gel electrophoresis (COMET assay) is a sensitive and well-established technique for quantifying DNA damage in individual cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, the single or integrated dose–response curves of these genes were distinctive from the conventional models obtained by the gamma-H2AX or comet assays. In comparison, rice displayed a higher dose-dependency in the comet signal and OsRAD51 transcription, while the gamma-H2AX induction was more dose-dependent in Arabidopsis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso