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641por Vasudevan, Arumugam, Srinivasan, Suganya, Vinayagam, Stalin, Ramkumar, Govindarajalou, Senthilnathan, Muthapillai“…RESULTS: The incidence of insufflation indicated by “comet tail” artifacts during FMV was lower in group CP (17 vs 71%; P < 0.001). …”
Publicado 2018
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642por Gunasekaran, Srilathaa, Dhiman, Rebika, Vanathi, Murugesan, Mohanty, Sujatha, Satpathy, Gita, Tandon, Radhika“…PURPOSE: The purpose of this study is to analyze the ocular surface microbial flora in patients with chronic limbal stem cell deficiency (LSCD) due to Stevens–Johnson Syndrome (SJS) and ocular chemical injury undergoing cultivated oral mucosal epithelial transplantation (COMET). METHODS: Patients of SJS and chemical injury who had bilateral total LSCD planned for COMET were studied. …”
Publicado 2019
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643por Chung, Young-Shin, Ahn, Jun-Ho, Eum, Ki-Hwan, Choi, Seon-A, Oh, Se-Wook, Kim, Yun-Ji, Park, Sue Nie, Yum, Young-Na, Kim, Joo-Hwan, Lee, Michael“…No statistically significant increase in the number of metaphases with structural aberrations was observed at the concentrations of 1.25, 2.5, and 5 µl/ml. The in vitro comet assay and micronucleus test results obtained on L5178Y cells also revealed that WSF has no genotoxicity potential, although there was a marginal increase in micronuclei frequencies and DNA damage in the respective micronucleus and comet assays. …”
Publicado 2008
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644por Rubin, Martin, Engrand, Cécile, Snodgrass, Colin, Weissman, Paul, Altwegg, Kathrin, Busemann, Henner, Morbidelli, Alessandro, Mumma, Michael“…Primitive objects like comets hold important information on the material that formed our solar system. …”
Publicado 2020
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645por Georgi, Fanny, Andriasyan, Vardan, Witte, Robert, Murer, Luca, Hemmi, Silvio, Yu, Lisa, Grove, Melanie, Meili, Nicole, Kuttler, Fabien, Yakimovich, Artur, Turcatti, Gerardo, Greber, Urs F.“…Here, we show that nelfinavir inhibits lytic cell-free transmission of HAdV, indicated by the suppression of comet-shaped infection foci in cell culture. Comet-shaped foci occur upon convection-based transmission of cell-free viral particles from an infected cell to neighboring uninfected cells. …”
Publicado 2020
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646“…REGISTRATION: This study is registered with the COMET database. https://www.comet-initiative.org/Studies/Details/1931. …”
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647por Singh, Asem Robinson, Singh, Salam Asbin, Singh, Thangjam Davis, Singh, Naorem Tarundas, Machathoibi, Takhellambam Chanu, Singh, Okram Mukherjee, Singh, Lisam Shanjukumar“…Kurz induces genomic DNA fragmentation, comet formation, and the inhibition of cell proliferation in the prostate cancer cell line PC3, as assessed by agarose gel electrophoresis, comet assay and MTT assay, respectively. …”
Publicado 2022
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648por Patel, Zabin S., Philips, Dominique, Casline, Elizabeth, Aarons, Gregory A., Maxwell, Colleen A., Ginsburg, Golda S., Ehrenreich-May, Jill, Jensen-Doss, Amanda“…After controlling for demographics and professional characteristics, COMET clinicians held more positive attitudes towards EBPs and MBC compared to national survey samples. …”
Publicado 2022
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649“…Mapping to the COMET Taxonomy showed that neither tool considered the impact of ‘Role Functioning’ on the person’s experience of dysphagia. …”
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650por Moretti, M, Villarini, M, Scassellati-Sforzolini, G, Monarca, S, Libraro, M, Fatigoni, C, Donato, F, Leonardis, C, Perego, L“…Peripheral blood lymphocytes were analyzed for the presence of DNA damage (single-cell microgel-electrophoresis, or comet assay) and for cytogenetic parameters (sister chromatid exchanges and micronuclei frequency, and proliferative rate index). …”
Publicado 1996
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651“…Epidemiologic studies support the use of chromosomal breakage as a relevant biomarker of cancer risk. The use of the Comet assay and methods analyzing oxidative DNA damage needs reliable validation for human biomonitoring. …”
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652“…The DNA damage of PBMC and PMN was evaluated based on the comet assay using visual scoring (arbitrary units). …”
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653por Szumilak, Marta, Merecz, Anna, Strek, Malgorzata, Stanczak, Andrzej, Inglot, Tadeusz W., Karwowski, Boleslaw T.“…Genotoxicity of the compounds was estimated by a comet assay. It has been shown that only compound 2a can interact with dsDNA via an intercalative binding mode as it displaced EtBr from the dsDNA-dye complex, with K(app) = 4.26 × 10(6) M(−1); caused an increase in melting temperature; changed the circular dichroism spectrum of dsDNA; converted relaxed plasmid DNA into a supercoiled molecule in the presence of Topo I and reduced the amount of short oligonucleotide fragments in the comet tail. …”
Publicado 2016
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654por Du, Yanan, Wang, Yan, Du, Liqing, Xu, Chang, Ji, Kaihua, Wang, Jinhan, Liu, Qiang“…DNA damage was detected using comet assay; the DNA percentage in the comet tail (TDNA%), tail moment (TM), and Olive tail moment (OTM) were recorded to describe DNA damage to lymphocytes and spermatozoa. …”
Publicado 2018
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655por Zani, Claudia, Donato, Francesco, Ceretti, Elisabetta, Pedrazzani, Roberta, Zerbini, Ilaria, Gelatti, Umberto, Feretti, Donatella“…A positive correlation was also found between in vitro comet test on leukocytes and PAHs in the PM(3–10) fraction. …”
Publicado 2021
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656por Scott, Madeleine K D, Quinn, Katie, Li, Qin, Carroll, Robert, Warsinske, Hayley, Vallania, Francesco, Chen, Shirley, Carns, Mary A, Aren, Kathleen, Sun, Jiehuan, Koloms, Kimberly, Lee, Jungwha, Baral, Jessika, Kropski, Jonathan, Zhao, Hongyu, Herzog, Erica, Martinez, Fernando J, Moore, Bethany B, Hinchcliff, Monique, Denny, Joshua, Kaminski, Naftali, Herazo-Maya, Jose D, Shah, Nigam H, Khatri, Purvesh“…In two validation cohorts (COMET trial and the Yale cohort), patients with higher monocyte counts were at higher risk for poor outcomes (COMET Wilcoxon p=0·025; Yale Wilcoxon p=0·049). …”
Publicado 2019
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657“…The results showed that the enzyme-sensitive sites were readily detected with the alkaline comet assay after the cells were treated with 10 microM As for 2 hr. …”
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658“…MATERIALS AND METHODS: Single-cell gel electrophoresis (comet assay) detects migration of DNA from individual cell nuclei following alkaline treatment. …”
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659“…The DNA damage involving the 25S rDNA sequences was analyzed using the comet-FISH technique. Fragmentation within or near the 25S rDNA involved the loci on the A and B chromosomes. …”
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660por Brooklyin, Sivakumar, Jana, Rashmoni, Aravinthan, Singaravelu, Adhisivam, Bethou, Chand, Parkash“…The amount of damaged DNA, measured as the tail length of the comet in cases, was 19.4±8.9 μm and the mean percentage of DNA in tail was 16.5±3.7. …”
Publicado 2014
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