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661“…In this study, we sought to elucidate the process of DNA degradation in brain and dental pulp cells of mice, within postmortem 0–72 hours, by using the single cell gel electrophoresis assay and professional comet image analysis and processing techniques. The frequency of comet-like cells, the percentage of tail DNA, tail length, tail moment, Olive moment and tail area increased in tandem with increasing postmortem interval. …”
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662por Reis, Surya A., Ghosh, Balaram, Hendricks, J. Adam, Szantai-Kis, D. Miklos, Törk, Lisa, Ross, Kenneth N., Lamb, Justin, Read-Button, Willis, Zheng, Baixue, Wang, Hongtao, Salthouse, Christopher, Haggarty, Stephen J., Mazitschek, Ralph“…COMET probes may translate into novel therapeutic strategies for diseases where conditional and selective epigenome modulation is required.…”
Publicado 2016
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663por Sirikhansaeng, Prapaparn, Tanee, Tawatchai, Sudmoon, Runglawan, Chaveerach, Arunrat“…Medicinal plants in genus Lagerstroemia were investigated for phytochemical contents by GC-MS and HPLC with ethanol and hexane extracts and their toxicity MTT and comet assay on human peripheral blood mononuclear cells (PBMCs). γ-Sitosterol is the major component found in all species at 14.70–34.44%. …”
Publicado 2017
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664“…The current study was carried out to evaluate the genotoxic aspects of the aqueous extracts of the Tribulus terrestris fruits by comet assay and cytogenetic procedures conditions on cultured human peripheral blood lymphocyte. …”
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665por Rodriguez-Garraus, Adriana, Azqueta, Amaya, Vettorazzi, Ariane, López de Cerain, Adela“…A total of 43 articles that used well-established standard assays (i.e., in vitro mouse lymphoma assays, in vitro micronucleus tests, in vitro comet assays, in vivo micronucleus tests, in vivo chromosome aberration tests and in vivo comet assays), were selected. …”
Publicado 2020
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666por Toida, Kazuma, Kushida, Wakana, Yamamoto, Hiroki, Yamamoto, Kyoka, Ishii, Kaichi, Uesaka, Kazuma, Kanaly, Robert A., Kutsuna, Shinsuke, Ihara, Kunio, Fujita, Yuichi, Iwasaki, Hideo“…However, we isolated a spontaneous mutant strain that shows active motility (gliding activity) to give rise to complicated colony patterns, including comet-like wandering clusters and disk-like rotating vortices on solid media. …”
Publicado 2023
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667por El Mesallamy, Hala O, Metwally, Nadia S, Soliman, Mahmoud S, Ahmed, Kawkab A, Abdel Moaty, Mai M“…In addition, silymarin and EGb significantly decreased comet assay parameters. Histopathological examination of rat livers treated with either silymarin or EGb exhibited an improvement in the liver architecture compared to NDEA group. …”
Publicado 2011
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668por Behravan, Effat, Moallem, Seyed Adel, Khateri, Shahriar, Maraghi, Elham, Jowsey, Paul, Blain, Peter G, Balali-Mood, Mahdi“…CONCLUSION: SM exposure of the veterans revealed DNA damage as judged by the comet assay.…”
Publicado 2013
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669por Babazadeh, Beheshteh, Sadeghnia, Hamid Reza, Safarpour Kapurchal, Elham, Parsaee, Heydar, Nasri, Sima, Tayarani-Najaran, Zahra“…The amount of DNA in the comet tail (% tail DNA) was measured as an indicator of DNA damage. …”
Publicado 2012
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670por Arslan, Gozde, Altintoprak, Kubra Murzoglu, Yirgin, Inci Kizildag, Atasoy, Mehmet Mahir, Celik, Levent“…Additionally, the presence of comet tail sign which a tail extending from an enhancing breast lesion into the parenchyma and might represent ductal infiltration on post-contrast series was also noted. …”
Publicado 2016
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671por Cissen, Maartje, van Wely, Madelon, Scholten, Irma, Mansell, Steven, de Bruin, Jan Peter, Mol, Ben Willem, Braat, Didi, Repping, Sjoerd, Hamer, Geert“…Importantly, for the TUNEL assay, SCD test and Comet assay, meta-regression showed no differences in predictive value between IVF and ICSI. …”
Publicado 2016
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672por Jeon, Hye Lyun, Yi, Jung-Sun, Kim, Tae Sung, Oh, Youkyung, Lee, Hye Jeong, Lee, Minseong, Bang, Jin Seok, Ko, Kinarm, Ahn, Il Young, Ko, Kyungyuk, Kim, Joohwan, Park, Hye-Kyung, Lee, Jong Kwon, Sohn, Soo Jung“…Here, we modified the OECD TG 489 and optimized the in vitro comet assay in our previous study. This study aimed to verify the validity of in vitro tests involving mSSCs by comparing their results with those of in vivo tests using C57BL/6 mice by gavage. …”
Publicado 2017
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673“…METHODS: A random sample of 50 TUS videos (16‐s duration) were scored by 6 raters with various levels of TUS expertise. Lung consolidation, comet tail artifacts, pleural irregularity and effusion were scored. …”
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674“…Of the 77 (81%) applicants that did not mention COMET or COS in their application, eight stated in the survey that they had searched the COMET database and ten carried out a search using another method. …”
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675por Bussolaro, Daniel, Wright, Stephanie L., Schnell, Sabine, Schirmer, Kristin, Bury, Nicolas R., Arlt, Volker M.“…Interestingly, comet formation was substantially increased (∼4-fold) when RTgutGC cells were exposed to PS-MBs (50 μg mL(−1)) and 10 μM 3-NBA compared to cells treated with 3-NBA alone. …”
Publicado 2019
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676“…These studies have been added to the COMET database, which now contains 370 published (1981–2019) COS studies for clinical research. …”
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677“…CONCLUSIONS: The high-throughput comet assay represents a sensitive tool for monitoring discrete changes in DNA integrity and assessing the viability status in plant germplasm processed for long-term storage. …”
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678por Keim-Malpass, Jessica, Ratcliffe, Sarah J, Moorman, Liza P, Clark, Matthew T, Krahn, Katy N, Monfredi, Oliver J, Hamil, Susan, Yousefvand, Gholamreza, Moorman, J Randall, Bourque, Jamieson M“…This tool, Continuous Monitoring of Event Trajectories (CoMET), has been shown in retrospective observational studies to predict clinical decompensation on the acute care ward. …”
Publicado 2021
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679por Colin, Alexandra, Kotila, Tommi, Guérin, Christophe, Orhant‐Prioux, Magali, Vianay, Benoit, Mogilner, Alex, Lappalainen, Pekka, Théry, Manuel, Blanchoin, Laurent“…We used the speed and the size of the actin comet tails to evaluate the system's monomer consumption and its lifetime. …”
Publicado 2023
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680“…Here, we identify a MAD2 (mitotic arrest deficient‐2) interaction motif in the C‐terminus of SERT, which binds the closed conformation of MAD2 and allows for the recruitment of two additional mitotic spindle assembly checkpoint (SAC) proteins, BubR1 and p31(comet), and of AP2. We visualize MAD2, BubR1, and p31(comet) in dorsal raphe neurons, and depletion of MAD2 in primary serotonergic rat neurons decreases SERT endocytosis in the soma. …”
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