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701por Silano, Vittorio, Bolognesi, Claudia, Castle, Laurence, Cravedi, Jean‐Pierre, Engel, Karl‐Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Husøy, Trine, Kärenlampi, Sirpa, Mennes, Wim, Milana, Maria Rosaria, Penninks, André, Smith, Andrew, Tavares Poças, Maria de Fátima, Tlustos, Christina, Wölfle, Detlef, Zorn, Holger, Zugravu, Corina‐Aurelia, Binderup, Mona‐Lise, Crebelli, Riccardo, Marcon, Francesca, Marzin, Daniel, Mosesso, Pasquale, Anastassiadou, Maria, Carfì, Maria, Saarma, Siiri, Gürtler, Rainer“…An in vivo Comet assay in liver and duodenum was provided that suggests that 4,5‐epoxydec‐2(trans)‐enal [FL‐no: 16.071] did not induce DNA damage in the duodenum of rats. …”
Publicado 2017
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702por Marschall, Raphael, Skorov, Yuri, Zakharov, Vladimir, Rezac, Ladislav, Gerig, Selina-Barbara, Christou, Chariton, Dadzie, S. Kokou, Migliorini, Alessandra, Rinaldi, Giovanna, Agarwal, Jessica, Vincent, Jean-Baptiste, Kappel, David“…A comet is a highly dynamic object, undergoing a permanent state of change. …”
Publicado 2020
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703por Assmann, Sadé, Keszthelyi, Daniel, Kleijnen, Jos, Kimman, Merel, Anastasiou, Foteini, Bradshaw, Elissa, Carrington, Emma, Chiarioni, Giuseppe, Maeda, Yasuko, Muris, Jean, Pohl, Daniel, Rydningen, Mona, Vaizey, Carolynne, Breukink, Stephanie“…TRIAL REGISTRATION: This project has been registered in the COMET database on the 1st of April 2020, available at http://www.comet-initiative.org/Studies/Details/1554. …”
Publicado 2021
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704por Arpini, Anna Paula, De Lorenzo, Andrea, Moritz, Aniele, Pereira, Julia Passarelli, Dias, Glauber Monteiro“…Single-cell gel electrophoresis (comet assay) was performed with blood lymphocytes to detect strand breaks, which determine a “comet tail” of variable size, visually scored by 3 observers in a fluorescence microscope after staining (0: no damage, no tail; 1: small damage; 2: large damage; 3: full damage). …”
Publicado 2022
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705por Komai, Seitaro, Inatomi, Tsutomu, Nakamura, Takahiro, Ueta, Mayumi, Horiguchi, Go, Teramukai, Satoshi, Kimura, Yasuko, Kagimura, Tatsuo, Fukushima, Masanori, Kinoshita, Shigeru, Sotozono, Chie“…BACKGROUND/AIMS: To investigate the long-term outcomes of cultivated oral mucosal epithelial transplantation (COMET) for fornix reconstruction in eyes with chronic cicatrising disease. …”
Publicado 2022
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706por Ubbink, Rinse, Streng, Lucia W. J. M., Raat, Nicolaas J. H., Harms, Floor A., te Boekhorst, Peter A. W., Stolker, Robert J., Mik, Egbert G.“…The aims of this pilot study were to investigate the effect of a red blood cell transfusion on mitochondrial oxygenation as measured by the COMET device in chronic anemia patients and to explore the clinical usability of the COMET monitor in blood transfusion treatments, especially the feasibility of performing measurements in an outpatient setting. …”
Publicado 2023
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707por Srám, R J“…For this review papers reporting the effect of GSTM1 genotype on DNA adducts, protein adducts, urine mutagenicity, Comet assay parameters, chromosomal aberrations, sister chromatid exchanges (SCE), micronuclei, and hypoxanthine-guanine phosphoribosyl transferase mutations were assessed. …”
Publicado 1998
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708por Alvarez-Moya, Carlos, Silva, Mónica Reynoso, Arámbula, Alma Rosa Villalobos, Sandoval, Alfonso Islas, Vasquez, Hugo Castañeda, González Montes, Rosa María“…In this work, various concentrations of a glyphosate isopropylamine salt were tested using two methods of genotoxicity assaying, viz., the pink mutation assay with Tradescantia (4430) and the comet assay with nuclei from staminal cells of the same plant. …”
Publicado 2011
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709por Romeo, Stefania, Zeni, Luigi, Sarti, Maurizio, Sannino, Anna, Scarfì, Maria Rosaria, Vernier, P. Thomas, Zeni, Olga“…A dose-dependent reduction in alkaline comet-assayed DNA migration is observed immediately after nsPEF exposure, accompanied by permeabilization of the plasma membrane (YO-PRO-1 uptake). …”
Publicado 2011
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710por Hintzsche, Henning, Jastrow, Christian, Kleine-Ostmann, Thomas, Kärst, Uwe, Schrader, Thorsten, Stopper, Helga“…DNA strand breaks and alkali-labile sites were quantified with the comet assay. No DNA strand breaks or alkali-labile sites were observed as a consequence of exposure to terahertz electromagnetic fields in the comet assay. …”
Publicado 2012
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711por Vadivelu, Raja Kumar, Yeap, Swee Keong, Ali, Abdul Manaf, Hamid, Muhajir, Alitheen, Noorjahan Banu“…Nevertheless, betulinic acid exhibited G(1) cell cycle arrest in flow cytometry cell cycle profiling and low level of DNA damage against VSMC in acridine orange/propidium iodide and comet assay after 24 h of treatment. In conclusion, betulinic acid induced G(1) cell cycle arrest and dose-dependent DNA damage on VSMC.…”
Publicado 2012
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712por da Silva, Fernanda R., Erdtmann, Bernardo, Dalpiaz, Tiago, Nunes, Emilene, Ferraz, Alexandre, Martins, Tales L.C., Dias, Johny F., da Rosa, Darlan P., Porawskie, Marilene, Bona, Silvia, da Silva, Juliana“…DNA damage was evaluated using the micronucleus test and the Comet assay and the concentration of cytochrome P450 enzymes was estimated. …”
Publicado 2013
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713“…The oxidative DNA damage level was measured with comet assay containing Fpg/Endo III cleavage, and the BER activity was estimated with a modified comet assay including nuclear extract of lymphocytes for enzymatic cleavage. …”
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714por Rosenberger, Albert, Rössler, Ute, Hornhardt, Sabine, Sauter, Wiebke, Bickeböller, Heike, Wichmann, H.-Erich, Gomolka, Maria“…DNA damage analysis was performed by alkaline comet assay before and after in vitro irradiation of isolated lymphocytes. …”
Publicado 2012
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715por Thomas, Emilia G., Šrut, Maja, Štambuk, Anamaria, Klobučar, Göran I. V., Seitz, Alfred, Griebeler, Eva Maria“…Microsatellite analysis suggested that Dp had undergone a genetic bottleneck. Comet assay did not indicate any difference in DNA damage between the two populations, but MNT revealed that Dp had an increased percentage of micronuclei in hemocytes in comparison to Cl. …”
Publicado 2014
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716por Oliveira, R.J., Mantovani, M.S., da Silva, A.F., Pesarini, J.R., Mauro, M.O., Ribeiro, L.R.“…In addition, the comet assay and the micronucleus test were also performed on peripheral blood cells of 54 male Swiss mice, 35 g each, to assess the effects of the compounds in vivo. …”
Publicado 2014
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717por Eskandani, Morteza, Dadizadeh, Elmira, Hamishehkar, Hamed, Nazemiyeh, Hossein, Barar, Jaleh“…Furthermore, Annexin V/PI staining and comet assay were used to study genotoxicity of compounds. …”
Publicado 2014
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718“…Slides were analyzed using fluorescence microscope and comet patterns were assessed. RESULTS: The mutagenicity index in addicted group was robustly higher than healthy volunteers. …”
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719por Ye, Qiaozhen, Rosenberg, Scott C, Moeller, Arne, Speir, Jeffrey A, Su, Tiffany Y, Corbett, Kevin D“…We propose that TRIP13 and p31(comet) collaborate to inactivate the spindle assembly checkpoint through MAD2 conformational conversion and disassembly of mitotic checkpoint complexes. …”
Publicado 2015
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720por Alvarez-Moya, Carlos, Reynoso-Silva, Mónica, Canales-Aguirre, Alejandro A., Chavez-Chavez, José O., Castañeda-Vázquez, Hugo, Feria-Velasco, Alfredo I.“…The comet assay can be used to assess genetic damage, but heterogeneity in the length of the tails is frequently observed. …”
Publicado 2015
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