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821por Lori, Gabriele, Tassinari, Roberta, Narciso, Laura, Udroiu, Ion, Sgura, Antonella, Maranghi, Francesca, Tait, Sabrina“…Cytotoxicity, apoptosis, necrosis and intracellular reactive oxygen species (ROS), comet assay and a micronucleus test with CREST immunofluorescence were used. …”
Publicado 2021
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822por Sajid, Moniba, Khan, Muhammad Rashid, Shah, Naseer Ali, Ullah, Shafi, Younis, Tahira, Majid, Muhammad, Ahmad, Bushra, Nigussie, Dereje“…DNA damages were investigated with comet assay in renal tissues while the oxidative injuries were estimated in serum and renal tissues. …”
Publicado 2016
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823por Richardson, Ebony, McEwen, Alison, Newton-John, Toby, Manera, Karine, Jacobs, Chris“…This core outcome set will support the standardisation of outcome reporting in reproductive carrier screening research and contribute to an evolving literature on outcomes to evaluate genetic testing and genetic counselling as health interventions. COMET CORE OUTCOME SET REGISTRATION: http://www.comet-initiative.org/Studies/Details/1381.…”
Publicado 2021
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824por Bond, Peter“…Bond’s perspective provides a much-needed overview, but it also details the very human feelings that animated the intense rivalries between the Soviet Union and the United States, and most recently the difficulties that arose in collaborations between NASA and ESA on the Rosetta and Halley's Comet missions.…”
Publicado 2007
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825por Moore, Sir Patrick“… All those nagging questions you have about the universe are answered here, like 'Is there a dark side to the moon? What happens when a comet hits the sun? Do the Martian canals have any water in them? …”
Publicado 2011
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826por Alafaleq, Nouf Omar, Zughaibi, Torki A., Jabir, Nasimudeen R., Khan, Azhar U., Khan, Mohd Shahnawaz, Tabrez, Shams“…A battery of biological assays, viz. neutral red uptake (NRU) assay, in vitro scratch assay, and comet assay, were performed for anticancer efficacy evaluation. …”
Publicado 2023
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827por Schönrock, Nele, Tillmans, Frauke, Sebens, Susanne, Kähler, Wataru, Klapa, Sebastian, Rieger, Bente, Scherthan, Harry, Koch, Andreas“…DNA damage was examined before, directly after, and 24 h after exposure with an alkaline comet assay and detection of γH2AX+53BP1 colocalizing double-strand break (DSB) foci and apoptosis. …”
Publicado 2023
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828por Cetkovic Pecar, Tamara, Haveric, Anja, Caluk Klacar, Lejla, Haveric, Sanin, Dzaferspahic, Alen, Mehanovic, Mahira, Durmisevic, Irma, Dzaferspahic, Selma, Hadzic Omanovic, Maida“…Before sampling, detailed survey and informed consent have been provided by each participant. Comet assay in oral leukocytes and buccal micronucleus cytome (BMCyt) assay in exfoliated buccal cells were applied. …”
Publicado 2023
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829“…Similarly, there was no significant difference in DNA damage (comet assay), percentage of centromere positive and negative cells (MN-FISH test) compared to the solvent control. …”
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830por Rouhi, Leila, Cheedipudi, Sirisha M., Cathcart, Benjamin, Gurha, Priyatansh, Marian, Ali J.“…METHODS: The DNA strand breaks were detected by the single-cell gel electrophoresis or the comet assay and expression of selected proteins by immunoblotting. …”
Publicado 2023
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831“…Genotoxicity was assessed through comet assay. Results showed that both alone and drug combinations of varying concentrations exhibited greater zones of inhibition at higher concentrations. …”
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832por El-Atawy, Mohamed A., Alsubaie, Mai S., Alazmi, Mohammed L., Hamed, Ezzat A., Hanna, Demiana H., Ahmed, Hoda A., Omar, Alaa Z.“…Using the annexin V/PI and comet tests, respectively, treated MCF-7 cells with this IC(50) value of the Diarylthiourea 4 compound displayed a considerable increase in early and late apoptotic cells, as well as an intense comet nucleus in comparison to control cells. …”
Publicado 2023
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833por Srikanth, Prarthana, Chowdhury, Amit Roy, Low, Grace Kah Mun, Saraswathy, Radha, Fujimori, Akira, Banerjee, Birendranath, Martinez-Lopez, Wilner, Hande, M. Prakash“…Interestingly, telomeric fragments were detected in the comet tails as revealed by comet-fluorescence in situ hybridization analysis, suggestive of telomeric instability in AT (-/-) cells upon exposure to sodium arsenite or radiation. …”
Publicado 2022
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834por Siles, E., Villalobos, M., Jones, L., Guerrero, R., Eady, J. J., Valenzuela, M. T., Núñez, M. I., McMillan, T. J., Ruiz de Almodóvar, J. M.“…However, as the results obtained by the comet assay are not in agreement with the DNA ladder experiments, we suggest that the distinction between the degraded DNA produced by apoptosis and necrosis may be difficult by this technique. …”
Publicado 1998
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835por Yao, Ke, Wu, Wei, Wang, KaiJun, Ni, Shuang, Ye, PanPan, Yu, YiBo, Ye, Juan, Sun, LiXia“…DNA damage to HLECs was examined by alkaline comet assay and the phosphorylated form of histone variant H2AX (γH2AX) foci formation assay. …”
Publicado 2008
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836por Ahmad, Muhammad S, Mirza, Bushra, Hussain, Mukhtiar, Hanif, Muhammad, Ali, Saqib, Walsh, Michael J, Martin, Francis L“…Biochemical-cell signatures were also ascertained using attenuated total reflection Fourier-transform infrared (ATR-FTIR) spectroscopy. In the comet assay, organotin(IV) carboxylates induced significantly-elevated levels of DNA SSBs. …”
Publicado 2008
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837por Stevens, Jacqueline J., Graham, Barbara, Walker, Alice M., Tchounwou, Paul B., Rogers, Christian“…Results of the [(3)H]thymidine incorporation assay and comet assay revealed that exposure to arsenic trioxide affected DNA synthesis and exhibited genotoxic effects in human colon cancer cells.…”
Publicado 2010
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838por Buchanan, Ian M, Scott, Tamalee, Tandle, Anita T, Burgan, William E, Burgess, Teresa L, Tofilon, Philip J, Camphausen, Kevin“…DNA damage was quantitated by γH2AX foci and neutral comet assay. Growth kinetics of subcutaneous tumours was used to assess the effects of AMG102 on in vivo tumour radiosensitivity. …”
Publicado 2011
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839por Al Zabadi, Hamzeh, Ferrari, Luc, Sari-Minodier, Irène, Kerautret, Marie-Aude, Tiberguent, Aziz, Paris, Christophe, Zmirou-Navier, Denis“…Genotoxicity of urinary extracts was assessed by comet and micronucleus assays on a HepG2 cell line. …”
Publicado 2011
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840por Lavaggi, María L., Cabrera, Mauricio, Pintos, Cristina, Arredondo, Carolina, Pachón, Gisela, Rodríguez, Jorge, Raymondo, Stella, Pacheco, José Pedro, Cascante, Marta, Olea-Azar, Claudio, López de Ceráin, Adela, Monge, Antonio, Cerecetto, Hugo, González, Mercedes“…Electron spin resonance is used to confirm (•)OH production, alkaline comet assay to determine genotoxicity, and gel electrophoresis and flow cytometry to analyze DNA fragmentation and cell cycle distribution. …”
Publicado 2011
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