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Mostrando 841 - 860 Resultados de 3,134 Para Buscar '"comet"', tiempo de consulta: 0.27s Limitar resultados
  1. 841
    “…Acridine orange (AO) and ethidium bromide (EB) and Hoechst 33258 staining were adopted to assess the mode of cell death, Annexin V-Cy3 staining to evaluate one of the early apoptotic features, JC-1 staining to assess the mitochondrial membrane depolarization, comet assay for DNA fragmentation, and cell cycle analysis for the distribution of cells after treatment. …”
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    Antiproliferative property of n-hexane and chloroform extracts of Anisomeles malabarica (L). R. Br. in HPV16-positive human cervical cancer cells
  2. 842
    “…The genotoxic and cytotoxic effects were evaluated using the alkaline comet and trypan blue dye exclusion assays. DNA damage was evaluated using two genotoxicity parameters: tail length and comet frequency. …”
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    Evaluation of Genotoxic and Cytotoxic Effects in Human Peripheral Blood Lymphocytes Exposed In Vitro to Neonicotinoid Insecticides News
  3. 843
    “…Comet assay was performed in a subgroup of 26 individuals to determine the influence of selected SNPs on DNA damage. …”
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    Genetic polymorphisms in homologous recombination repair genes in healthy Slovenian population and their influence on DNA damage
  4. 844
    “…Using an FPG-modified Comet-assay as well as warm and cold repair incubation, we show that dsbs arise partially during repair of bi-stranded, oxidative, clustered DNA lesions. …”
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    UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages
  5. 845
    “…In SOS chromotest, using E.coli PQ37 tester strain, it inhibited induction factor induced by H(2)O(2) and 4NQO by 75.54% and 71.69% at the concentration of 121.46 μM,respectively. In Comet assay, it reduced the tail moment induced by H(2)O(2) and 4NQO by 70.21% and 69.04%, respectively, at the same concentration in human blood lymphocytes. …”
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    Modulation of genotoxicity of oxidative mutagens by glycyrrhizic acid from Glycyrrhiza glabra L.
  6. 846
    por Teh, Min Yan, Morona, Renato
    Publicado 2013
    “…The activated N-WASP then activates the Arp2/3 complex which initiates de novo actin nucleation and polymerisation to form F-actin comet tails and allows bacterial cell-to-cell spreading. …”
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    Identification of Shigella flexneri IcsA Residues Affecting Interaction with N-WASP, and Evidence for IcsA-IcsA Co-Operative Interaction
  7. 847
    “…Cytoplasm shrinkage and a significant decrease in the diameter of the nuclei were also seen. Comet assay and agarose gel electrophoresis revealed DNA breakage, while positive TUNEL and activated caspase 3 confirmed the apoptosis. …”
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    Low Dose and Long Term Toxicity of Sodium Arsenite Caused Caspase Dependent Apoptosis Based on Morphology and Biochemical Character
  8. 848
    “…Flow cytometry was employed for cell cycle analysis, DAPI staining, and the Comet assay was used for DNA fragmentation and DNA condensation. …”
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    Houttuynia cordata Thunb extract modulates G(0)/G(1) arrest and Fas/CD95-mediated death receptor apoptotic cell death in human lung cancer A549 cells
  9. 849
    “…DNA damage and repair were evaluated by alkaline comet assay and γH2AX foci assay. Using the comet assay, we observed a dose-dependent increase in DNA damage in both cell types. …”
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    Are mouse lens epithelial cells more sensitive to γ-irradiation than lymphocytes?
  10. 850
    “…In the plasmid relation and comet assay, the P. longifolia leaf extract exhibited strong inhibitory effects against H(2)O(2)-mediated DNA damage. …”
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    Evaluation of the Genotoxic Potential against H(2)O(2)-Radical-Mediated DNA Damage and Acute Oral Toxicity of Standardized Extract of Polyalthia longifolia Leaf
  11. 851
    “…In peripheral blood mononuclear cells of non-smoking individuals, non-obstructive smokers, patients with COPD of all stages and those with COPD exacerbation, we evaluated DNA damage, PARP activity and PARP-1 mRNA expression using Comet Assay IV, biotinylated-NAD incorporation assay and qRT-PCR, respectively and subjected results to ordinal logistic regression modelling. …”
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    Increased DNA Damage in Progression Of COPD: A Response By Poly(ADP-Ribose) Polymerase-1
  12. 852
    “…IC(50) values and cell doubling times were quantified using a real time cytotoxicity assay. COMET and γ-H2AX assays, cell cycle analysis, and apoptosis assessment further investigated the mechanisms of BLM resistance in these cell lines. …”
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    Resistance to Bleomycin in Cancer Cell Lines Is Characterized by Prolonged Doubling Time, Reduced DNA Damage and Evasion of G2/M Arrest and Apoptosis
  13. 853
    “…Methods to assess base and nucleotide excision repair pathways (BER and NER) in peripheral blood cells based on modified comet assay protocols have been widely applied in human epidemiological studies. …”
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    Functional evaluation of DNA repair in human biopsies and their relation to other cellular biomarkers
  14. 854
    “…Both the conventional phenotypic alkaline comet test and the newly developed quantitative toxicogenomics assay, that detects and quantifies molecular level changes in the regulation of six DNA damage repair pathways, were employed. …”
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    Comparative and Mechanistic Genotoxicity Assessment of Nanomaterials via a Quantitative Toxicogenomics Approach across Multiple Species
  15. 855
    “…DNA and chromosomal damage in peripheral blood leukocytes of patients with coronary artery disease (CAD) were investigated by using the single cell gel electrophoresis assay /comet and cytokinesis- block micronucleus (CBMN) assays, respectively. …”
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    DNA and chromosomal damage in coronary artery disease patients
  16. 856
    “…The relative expression level of γ-H2AX and percentage of cells with comet tails were elevated in pEGFP-UL76 or pEGFP-UL76C transfection groups compared to the control. …”
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    Unconserved C terminal of human cytomegalovirus tegument protein pUL76 elicits nuclear aggresome formation and induces DNA damage in transfected cells
  17. 857
    “…CHO-K1 cells were used in vitro micronucleus (MNvit) and comet assays. Two strains of Salmonella typhimurium (Salmonella enterica subsp.enterica; TA98 and TA1537) were employed in Ames tests. …”
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    Comparative evaluation of the mutagenicity and genotoxicity of smoke condensate derived from Korean cigarettes
  18. 858
    “…The results suggest that neither Comet nor ParentSteps had beneficial effects on adolescent’s antisocial or delinquent behavior, or on alcohol use. …”
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    Parent Programs for Reducing Adolescent’s Antisocial Behavior and Substance Use: A Randomized Controlled Trial
  19. 859
    “…RESULTS: By applying the two methods, cell-free DNA and comet assay, we found a significant increase in the extent of DNA damage in the exposed individuals compared with the non-exposed ones within the control group. …”
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    Quantification of cell-free DNA for evaluating genotoxic damage from occupational exposure to car paints
  20. 860
    “…The results demonstrated that equol induced an apoptotic nuclear morphology revealed by AO/EB staining, the presence of a comet tail, the cleavage of caspase-3 and PARP and the depletion of cIAP1, indicating its pro-apoptotic effect. …”
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    Equol Induces Mitochondria-Dependent Apoptosis in Human Gastric Cancer Cells via the Sustained Activation of ERK1/2 Pathway
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