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861“…The mechanism of antiproliferation activity of MEAC was investigated through morphological studies by acridine orange (AO)/ethidium bromide (EB) double staining method. Comet assay was estimated to check the DNA damage induced apoptosis property. …”
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862por Gorst, Sarah L., Gargon, Elizabeth, Clarke, Mike, Smith, Valerie, Williamson, Paula R.“…BACKGROUND: The COMET (Core Outcome Measures in Effectiveness Trials) Initiative promotes the development and application of core outcome sets (COS), including relevant studies in an online database. …”
Publicado 2016
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863“…These studies measured DNA damage (by one of four assays: 23 SCSA, 18 TUNEL, 8 SCD, and 7 Comet) and included a total of 8068 treatment cycles (3734 IVF, 2282 ICSI, and 2052 mixed IVF + ICSI). …”
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864por Verschaeve, Luc, Edziri, Hayet, Anthonissen, Roel, Boujnah, Dalenda, Skhiri, Fethia, Chehab, Hechmi, Aouni, Mahjoub, Mastouri, Maha“…The neutral Red Uptake test, Vitotox and alkaline comet assay were used. Leaf extracts from 4 different origins were investigated. …”
Publicado 2017
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865por Janati Esfahani, Azam, Mahdavi, Seied Rabi, Shiran, Mohammad Bagher, Khoei, Samideh“…The results of the TEF assay were 2.54 from the comet assay and 2.33 according to flow cytometry. …”
Publicado 2017
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866por Kadioglu, Onat, Chan, Ariel, Cong Ling Qiu, Alena, Wong, Vincent Kam Wai, Colligs, Vanessa, Wecklein, Sabine, Freund-Henni Rached, Halima, Efferth, Thomas, Hsiao, Wen-Luan Wendy“…Five compounds that showed comparable binding energies and similar docking poses were selected for in vitro cytotoxicity test and Comet assay for DNA damage. WWLL-013, WWLL-022, and WWLL-1098 showed the lowest binding energy also induced DNA damage in the Comet assay. …”
Publicado 2017
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867por Atli, Ozlem, Baysal, Merve, Aydogan-Kilic, Gozde, Kilic, Volkan, Ucarcan, Seyda, Karaduman, Burak, Ilgin, Sinem“…One-way ANOVA, post-hoc Dunnett's T3 test for the sperm comet assay, and post-hoc Tukey's test for the others were performed for statistical analysis. …”
Publicado 2017
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868“…The radioprotective potential was analysed by bone marrow micronucleus test and comet assay in peripheral blood lymphocytes. Biochemical estimations were performed in liver tissue homogenates. …”
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869“…Western blotting was conducted to test the activation of the apoptotic pathway. The comet assay was used to determine the DNA damage induced by loperamide. …”
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870por Webbe, James, Brunton, Ginny, Ali, Shohaib, Duffy, James MN, Modi, Neena, Gale, Chris“…TRIAL REGISTRATION NUMBER: Core Outcome Measures in Effectiveness Trials (COMET) database: 842 (www.comet-initiative.org/studies/details/842).…”
Publicado 2017
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871por Sadeghi, Fatemeh, Etebari, Mahmoud, Habibi Roudkenar, Mehryar, Jahanian-Najafabadi, Ali“…MTT assay of the Lcn2 over-expressing cells showed higher IC50 values comparing to the non-transfected cells. Furthermore, the Comet assay confirmed Lcn2 protective effects on the cisplatin (1 µg/mL) induced genotoxicity. …”
Publicado 2018
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872por Mo, Li-Jun, Song, Man, Huang, Qiao-Hua, Guan, Hua, Liu, Xiao-Dan, Xie, Da-Fei, Huang, Bo, Huang, Rui-Xue, Zhou, Ping-Kun“…To monitor DNA damage and repair efficiency, the DNA double-strand break biomarker 53BP1 foci, comet, micronuclei, expression of DNA repair genes and NHEJ repair activity were detected. …”
Publicado 2018
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873por De Mattos, José Carlos Pelielo, de Matos, Vanessa Coutinho, Rodrigues, Michelle Pinheiro, de Oliveira, Marcia Betânia Nunes, Dantas, Flavio José S., Santos-Filho, Sebastião David, Bernardo-Filho, Mario, Caldeira-de-Araujo, Adriano“…(positive control), SnCl(2) 500 μg/mL or (99m)Tc-MDP to animals and blood samples taken immediately before the injection, 3, and 24 h after (in the Comet assay) and 36 h after, for micronucleus test. …”
Publicado 2012
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874“…Micronucleus frequency (micronucleus test MNT) and DNA damage (comet assay) were performed in the bone marrow cells and leukocytes, respectively. …”
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875por Aramburú Junior, Jaime Sardá, Eilers Treichel, Tiago Luis, Lemos Pinto Filho, Saulo Tadeu, Gehrke, Sergio Alexandre, Machado, Alencar Kolinski, Cadoná, Francine Carla, Mânica da Cruz, Ivana Beatrice, Pippi, Ney Luis“…The aim of this study was to evaluate the potential use of a DNA comet assay, DNA fragmentation fluorimetric assay and reactive oxygen species levels as potential biomarkers of genome conditions of dental pulp stem cells (DPSCs) isolated from dog canine teeth. …”
Publicado 2018
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876por Kopjar, Nevenka, Fuchs, Nino, Žunec, Suzana, Mikolić, Anja, Micek, Vedran, Kozina, Goran, Lucić Vrdoljak, Ana, Brčić Karačonji, Irena“…Even though DNA damage quantified by the alkaline comet assay is subject to repair, its elevated level detected in the brain cells of THC-treated rats was reason for concern. …”
Publicado 2019
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877“…Maximal area of lung consolidation also was associated with a higher relapse risk (OR, 1.052/cm(2); 1.009‐1.097) but not with ADG. Comet tails and pleural fluid were not associated with risk of relapse or ADG. …”
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878por Chung, Young-Shin, Eum, Ki-Hwan, Choi, Seon-A, Oh, Se-Wook, Park, Sue Nie, Yum, Young-Na, Kim, Joo-Hwan, Seo, Young-Rok, Lee, Michael“…Carrageenan was not considered to be clastogenic in this assay at up to the highest feasible concentration which could be evaluated. The in vitro comet assay and micronucleus test results obtained on L5178Y cells also revealed that carrageenan has no genotoxicity potential, although there was a marginal increase in micronuclei frequencies and DNA damage in the respective micronucleus and comet assays. …”
Publicado 2009
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879por Vales, Gerard, Suhonen, Satu, Siivola, Kirsi M., Savolainen, Kai M., Catalán, Julia, Norppa, Hannu“…In this study, we investigated the role of surface charge in determining the genotoxic potential of gold NPs, as measured by the induction of DNA damage (comet assay) and chromosomal damage (micronucleus assay) in human bronchial epithelial BEAS-2B cells. …”
Publicado 2020
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880por Seal, Tapan, Chaudhuri, Kausik, Pillai, Basundhara, Chakrabarti, Shrabana, Mondal, Tanmoy, Auddy, Biswajit“…The genotoxicity of the contemplated plant was tried by the single-cell gel electrophoresis comet measure. The DNA defensive impacts of the aqueous extracts of fruits on rodent lymphocyte DNA lesions were likewise assessed with the comet test. …”
Publicado 2020
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