Mostrando 921 - 940 Resultados de 3,134 Para Buscar '"comet"', tiempo de consulta: 0.34s Limitar resultados
  1. 921
    “…DNA damage was assessed in the HeLa and MS751 cells using alkaline comet assays and by detection of γH2AX focus formation. …”
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  2. 922
    “…RESULTS: No statistically significant differences were found in the bacterial mutation assay, in vitro chromosomal aberration test, in vivo comet assay, and in vivo micronucleus test when tested for induction of genotoxicity in both two types of SiO(2) nanoparticles. …”
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  3. 923
    “…DNA strand breaks in BAL cells, lung, and liver tissue were assessed using the alkaline comet assay. The pulmonary acute phase response was analyzed by Saa3 mRNA real-time quantitative PCR. …”
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  4. 924
    “…Urban dust and DEP produced comparable levels of DNA damage, as assessed by the alkaline comet assay, in MEFs at higher levels than those induced by Manchester PM. …”
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  5. 925
    “…Data generated from the comet assay indicated a concentration-dependent increase in DNA damage, showing a significant increase (p < 0.05) in comet tail-length and percentages of DNA cleavage. …”
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  6. 926
    “…Data obtained from the Comet assay indicated that cadmium chloride causes DNA damage in HepG(2) cells in a concentration-dependent manner. …”
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  7. 927
    “…Specifically, cell viability was evaluated by colorimetric assay; cytotoxicity by LDH release; apoptosis was determined by Western blotting, and morphological analysis with, acridine orange and neutral red stainings and comet assay; topoisomerase I activity was assessed using assay based upon DNA relaxation and topoisomerase II by DNA relaxation plus decatentation of kinetoplast DNA; lysosomal vacuolation and volume of acidic compartments (VAC) were evaluated with neutral red staining. …”
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  8. 928
  9. 929
    “…As the only particles, ZnO caused a significant toxic effect in the airways while TiO(2) gave rise to DNA-strand break as shown by the comet assay.…”
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  10. 930
  11. 931
    “…Neither TDF + 3TC nor combivir + EFV induced DNA damage at any concentrations tested after 24 h or 48 h using the comet assay. After 24 h, both combinations increased the micronucleus frequency at all concentrations tested. …”
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  12. 932
    “…Leaf extract of A. biebersteinii was not cytotoxic even at the highest examined dose (512 µg/ml) and inhibited cell toxicity induced by H(2)O(2) (98% viability for the cells pretreated with plant extract in the presence of H(2)O(2)). Comet assay also confirmed high DNA protective activity of leaf extracts. …”
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  13. 933
    “…HIC1 is also essential for DSB repair as silencing of endogenous HIC1 in BJ-hTERT fibroblasts significantly delays DNA repair in functional Comet assays. HIC1 SUMOylation favours its interaction with MTA1, a component of NuRD complexes. …”
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  14. 934
    “…We will actively disseminate our findings to help improve clinical trials, systematic reviews and clinical guidelines with the ultimate aim of improving the prevention and management of periodontal diseases. TRIAL REGISTRATION: COMET (http://www.comet-initiative.org/studies/details/265?…”
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  15. 935
  16. 936
    “…The inclusion of multiple stakeholder perspectives will increase the final COSs applicability and relevance. TRIAL REGISTRATION: Comet Initiative, COMET 1083; PROSPERO, CRD42018084853. …”
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  17. 937
    “…TRIAL REGISTRATION: The Core Outcome Measures in Effectiveness Trials Initiative (COMET): http://www.comet-initiative.org/studies/details/983. …”
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  18. 938
    “…MATERIALS AND METHODS: A total of nine human BTC cell lines were used for evaluating anti-tumor effect of AZD6738 (ATR inhibitor) alone or combination with cytotoxic chemotherapeutic agents through MTT assay, colony-forming assays, cell cycle analyses, and comet assays. We established SNU478-mouse model for in vivo experiments to confirm our findings. …”
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  19. 939
  20. 940
    “…Hence, maximum comet parameters (Tail length, Tail DNA and Olive Tail Moment) were observed in (in-organic Cr) by 0.3 mg/kg concentration. …”
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