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  1. 981
    “…DNA damage repair was analyzed by comet assay and immunofluorescence detection of γH2AX foci. …”
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    Radiosensitization and growth inhibition of cancer cells mediated by an scFv antibody gene against DNA-PKcs in vitro and in vivo
  2. 982
    “…CONCLUSION: Our study shows that the Comet/FLARE assay is a relatively rapid and useful method for determination of DNA repair capacity. …”
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    Rapid method for determination of DNA repair capacity in human peripheral blood lymphocytes amongst smokers
  3. 983
    “…Swimming was not associated with DNA damage detectable by the comet assay. Urine mutagenicity increased significantly after swimming, in association with the higher concentration of exhaled bromoform (p = 0.004). …”
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    Genotoxic Effects in Swimmers Exposed to Disinfection By-products in Indoor Swimming Pools
  4. 984
    “…DNA damage as measured by Comet assay was increased in HepG2 cells at all concentrations of Chlorella vulgaris tested. …”
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    Hot water extract of Chlorella vulgaris induced DNA damage and apoptosis
  5. 985
    “…METHODS: We measured urinary levels of four PAH metabolites and assessed semen quality, sperm apoptotic markers with Annexin V assay, and sperm DNA damage with comet assay in 232 men from Chongqing, China. RESULTS: We found that increased urinary 2-hydroxynaphthalene (2-OHNa) levels were associated with increased comet parameters, including the percentage of DNA in the tail (tail%) [β coefficient = 13.26% per log unit 2-OHNa (micrograms per gram creatinine); 95% confidence interval (CI), 7.97–18.55]; tail length (12.25; 95% CI, 0.01–24.52), and tail distribution (7.55; 95% CI, 1.28–18.83). …”
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    Association between Urinary Polycyclic Aromatic Hydrocarbon Metabolites and Sperm DNA Damage: A Population Study in Chongqing, China
  6. 986
    “…Genotoxic activity of samples was determined by comet assay. Identification of different compounds was carried out by gas chromatography- mass spectrometry analysis. …”
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    Insecticidal and genotoxic activity of Psoralea corylifolia Linn. (Fabaceae) against Culex quinquefasciatus Say, 1823
  7. 987
    “…Serotonin, interferon gamma (IFN-γ), and glutathione-s-transferase activity, together with Comet DNA were assayed in the brain tissue of rats in all different groups. …”
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    Protective and therapeutic potency of N-acetyl-cysteine on propionic acid-induced biochemical autistic features in rats
  8. 988
    “…These observations were strongly supported by increased caspase activity, increased comet tails using comet assays, and increased protein levels of apoptosis-associated molecules (caspase 3/9, cleaved PARP). …”
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    Combination Effect of Epigenetic Regulation and Ionizing Radiation in Colorectal Cancer Cells
  9. 989
    “…BACKGROUND: The COMET (Core Outcome Measures in Effectiveness Trials) Initiative is developing a publicly accessible online resource to collate the knowledge base for core outcome set development (COS) and the applied work from different health conditions. …”
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    Collating the knowledge base for core outcome set development: developing and appraising the search strategy for a systematic review
  10. 990
    “…A corresponding increase in oxidative damage to DNA was revealed by the formamidopyrimidine-DNA glycosylase (fpg)-modified comet assay. Without fpg, DNP-induced DNA damage detected by the comet assay was only found in Hepa1c1c7 cells. …”
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    Mechanisms linked to differences in the mutagenic potential of 1,3-dinitropyrene and 1,8-dinitropyrene
  11. 991
    “…TRIAL REGISTRATION: Registered 12 April 2015 at COMET (http://www.comet-initiative.org)…”
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    Outcomes in Trials for Management of Caries Lesions (OuTMaC): protocol
  12. 992
    “…MATERIALS AND METHODS: In this experimental study, comet assay and neutral red uptake (NRU) assay methods were used to determinacy to toxicity and genotoxicity of BA and hydrogen peroxide (H(2)O(2)). …”
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    Protective Effect of Boric Acid on Oxidative DNA Damage In Chinese Hamster Lung Fibroblast V79 Cell Lines
  13. 993
    “…METHODS: This study is a secondary analysis of the COMET trial, a pragmatic prospective Dutch multicenter before-after study. …”
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    Unexpected versus all-cause mortality as the endpoint for investigating the effects of a Rapid Response System in hospitalized patients
  14. 994
    “…Oxidative stress was evaluated in leukocytes using the COMET assay. Insulin, glucose, ketones, insulin-like growth factor-1 (IGF-1) and IGF binding proteins (IGFBPs) were measured as biomarkers of the fasting state. …”
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    Safety and feasibility of fasting in combination with platinum-based chemotherapy
  15. 995
    “…Cell cycle status was analyzed by checking DNA content after staining with PI. A comet assay was used to assess the DNA repair in the cells. …”
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    Chloroquine, an autophagy inhibitor, potentiates the radiosensitivity of glioma initiating cells by inhibiting autophagy and activating apoptosis
  16. 996
    “…Hoechst 33342/PI double staining and comet assay were used to examine the morphological characteristics of apoptosis and to examine the effects of rHSG on the apoptosis of the C6 cells. …”
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    Pro-apoptotic effects of rHSG on C6 glioma cells
  17. 997
    “…We will also explore the challenges of using online Delphi methods for this hard-to-reach population, and examine differences in opinion about which outcomes matter to diverse stakeholder groups. TRIAL REGISTRATION: COMET registration: http://www.comet-initiative.org/studies/details/911. …”
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    A core outcome set for evaluating self-management interventions in people with comorbid diabetes and severe mental illness: study protocol for a modified Delphi study and systematic review
  18. 998
    “…The plant immune response was measured within three days of virus infection using the cutoff value of H(2)O(2) (⩽1.095 μmol/100 mg) and (⩽3.201 units) for the tail moment in the Comet Assay. Their percentage changes were 255.12% and 522.40% respectively which reflects the stress of virus infection in the plant. …”
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    Physiological parameters correlated with Tomato Mosaic Virus inducing defensive response in Datura metel
  19. 999
    “…TRIAL REGISTRATION: The COS study, of which this is a part, is registered in the Core Outcome Measures in Effectiveness Trials (COMET) database, http://www.comet-initiative.org/studies/details/956. …”
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    Selecting Core Outcomes for Randomised Effectiveness trials In Type 2 Diabetes (SCORE-IT): study protocol for the development of a core outcome set
  20. 1000
    “…Regarding genotoxicity/mutagenicity, results showed fluconazole to increase significantly (P<0.05) DNA damage index, as assessed by comet assay, at 1306μM versus the negative control (DI=1.17 vs DI=0.28, respectively). …”
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    Cytotoxic and Genotoxic Effects of Fluconazole on African Green Monkey Kidney (Vero) Cell Line
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