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1101por Carey, B., Farag, A. M., Nasri-Heir, C., Klasser, G. D., Ariyawardana, A., Chmieliauskaite, M., Sardella, A., Carlson, C. R., Miller, C. S., Mejia, L., O’Neill, F. E., Albuquerque, R.“…METHODS: A BMS-specific COS will be developed using the method recommended by the Core Outcome Measures in Effective Trials (COMET) initiative (Registration: http://www.comet-initiative.org/studies/details/1357). …”
Publicado 2020
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1102por Quirke, Fiona A., Healy, Patricia, Bhraonáin, Elaine Ní, Daly, Mandy, Biesty, Linda, Hurley, Tim, Walker, Karen, Meher, Shireen, Haas, David M., Bloomfield, Frank H., Kirkham, Jamie J., Molloy, Eleanor J., Devane, Declan“…TRIAL REGISTRATION: This study is registered in the Core Outcome Measures for Effectiveness (COMET) database http://www.comet-initiative.org/Studies/Details/1270.…”
Publicado 2021
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1103por Vergote, Simen, De Bie, Felix, Bosteels, Jan, Hedrick, Holly, Duffy, James, Power, Beverley, Benachi, Alexandra, De Coppi, Paolo, Fernandes, Caraciolo, Lally, Kevin, Reiss, Irwin, Deprest, Jan“…METHODS: We will use the methodology described in the Core Outcome Measures in Effectiveness Trials (COMET) Initiative Handbook. An international steering group will be created to guide the development of the COS. …”
Publicado 2021
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1104por Bateman, Marcus, Evans, Jonathan P., Vuvan, Viana, Jones, Val, Watts, Adam C., Phadnis, Joideep, Bisset, Leanne, Vicenzino, Bill“…TRIAL REGISTRATION: Registered with the Core Outcome Measures in Effectiveness Trials (COMET) database, November 2019. https://www.comet-initiative.org/Studies/Details/1497.…”
Publicado 2021
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1105“…Furthermore, mammalian toxicity was analyzed with respect to DNA damage induced in treated rat relative to control by comet assay using different tissues of rat (blood, liver, and kidney). …”
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1106por Zheng, Yansong, Zhang, Hengce, Guo, Yueting, Chen, Yuan, Chen, Hanglong, Liu, Yingchun“…RESULTS: We found that knockdown of XRCC1 significantly increased β-lap-induced DNA double-strand breaks, comet tail lengths and cell death in PDA cells. Furthermore, we observed combining XRCC1 knockdown with β-lap treatment switched programmed necrosis with β-lap monotherapy to caspase-dependent apoptosis. …”
Publicado 2021
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1107“…TRIAL REGISTRATION: This study was registered in the database of Core Outcome Measures in Effectiveness Trials (COMET) on June11th, 2021 (https://comet-initiative.org/Studies/Details/1884).…”
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1108por Henry, Cían J., Semova, Gergana, Barnes, Ellen, Cotter, Isabel, Devers, Tara, Rafaee, Aisyah, Slavescu, Andreea, Cathain, Niamh O., McCollum, Danielle, Roche, Edna, Mockler, David, Allen, John, Meehan, Judith, Klingenberg, Claus, Latour, Jos M., van den Hoogen, Agnes, Strunk, Tobias, Giannoni, Eric, Schlapbach, Luregn J., Degtyareva, Marina, Plötz, Frans B., de Boode, Willem P., Naver, Lars, Wynn, James L., Küster, Helmut, Janota, Jan, Keij, Fleur M., Reiss, Irwin K. M., Bliss, Joseph M., Polin, Richard, Koenig, Joyce M., Turner, Mark A., Gale, Christopher, Molloy, Eleanor J.“…These were then assigned to seven different domains in line with the taxonomy for classification proposed by the COMET initiative. The most frequently reported outcome was survival with 74% (n = 67) of the studies reporting an outcome within this domain. …”
Publicado 2022
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1109por Harms, Floor A., Ubbink, Rinse, de Wijs, Calvin J., Ligtenberg, Max P., ter Horst, Maarten, Mik, Egbert G.“…CONCLUSION: This pilot study illustrated the feasibility of measuring cutaneous mitoPO(2) using the COMET(®) monitor during cardiothoracic procedures. …”
Publicado 2022
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1110por Siemionow, Maria, Brodowska, Sonia, Langa, Paulina, Zalants, Kristina, Kozlowska, Katarzyna, Grau-Kazmierczak, Wictoria, Heydemann, Ahlke“…No complications were observed after intraosseous transplant of human DEC. COMET assay of donors and fused DEC cells confirmed lack of DNA damage. …”
Publicado 2022
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1111por Mitchell, James W., Noble, Adam, Baker, Gus, Batchelor, Rachel, Brigo, Francesco, Christensen, Jakob, French, Jacqueline, Gil-Nagel, Antonio, Guekht, Alla, Jette, Nathalie, Kälviäinen, Reetta, Leach, John Paul, Maguire, Melissa, O’Brien, Terence, Rosenow, Felix, Ryvlin, Philippe, Tittensor, Phil, Tripathi, Manjari, Trinka, Eugen, Wiebe, Samuel, Williamson, Paula R., Marson, Tony“…CORE OUTCOME SET REGISTRATION: COMET Initiative as study 118.…”
Publicado 2022
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1112por Chapman, Lara S., Redmond, Anthony C., Flurey, Caroline A., Richards, Pamela, Smith, Toby O., Arnold, John B., Beaton, Dorcas, Conaghan, Philip G., Golightly, Yvonne M., Hannan, Marian T., Hofstetter, Catherine, Maxwell, Lara J., Menz, Hylton B., Shea, Beverley, Tugwell, Peter, Helliwell, Philip, Siddle, Heidi J.“…TRIAL REGISTRATION: This study is registered with the Core Outcome Measures in Effectiveness Trials (COMET) database, as of June 2022: https://www.comet-initiative.org/Studies/Details/2081…”
Publicado 2023
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1113por Kronk, Gary W“…The book also includes breakthroughs in the study of meteor showers, such as accurate predictions of outbursts as well as comet and meteor observations from the 6th century to the 17th century that were not published in the first edition. …”
Publicado 2014
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1114por Bignami, Giovanni F“…He will help us to discover the innovations that will have changed our lives by 2062, when, riding astride Halley’s Comet, our omniscient extraterrestrial will return to visit us.In this book, we shall learn how astronomers will devote themselves to the study of the mysterious force of dark energy, which makes up some three-quarters of the Universe. …”
Publicado 2014
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1115por Randall, Lisa“…In Dark Matter and the Dinosaurs, Lisa Randall proposes it was a comet that was dislodged from its orbit as the Solar System passed through a disk of dark matter embedded in the Milky Way. …”
Publicado 2015
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1116“…We demonstrate this by applying the pipeline to data sets generated by ThermoFinnigan LCQ, ABI 4700 MALDI-TOF/TOF, and Waters Q-TOF instruments, and searched in turn using SEQUEST, Mascot, and COMET.…”
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1117por Zha, Ying-ying, Yang, Bo, Tang, Ming-liang, Guo, Qiu-chen, Chen, Ju-tao, Wen, Long-ping, Wang, Ming“…At high concentrations, fullerenol induced apoptosis confirmed by Comet assay and assessment of caspase proteins. CONCLUSION: These findings suggest that fullerenol promotes cell death and protects against cell damage, depending on the concentration present. …”
Publicado 2012
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1118“…In this review the most common methods quantifying the three parameters mentioned above, the cytokinesis-block micronucleus assay, the comet assay, and the quantification of 8-oxo-7,8-dihydro-2′-deoxyguanosine, are evaluated concerning the feasibility of the analysis and regarding the marker's potential to predict clinical outcomes.…”
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1119“…In an analysis of dispersed cells from the ovaries, however, the cell viability of the vitrified/warmed group tended to be decreased. The results of a comet assay showed no significant differences in DNA damage. …”
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1120“…One form is called spreading, which is a type of sliding motility and the second form involves comet formation, which has many observable characteristics associated with gliding motility. …”
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