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  1. 1201
    “…Objective: Case report of a patient with angioid streaks, peau d’orange, comet tail lesions, choroidal neovascularisation and presumed pseudoxanthoma elasticum (PXE). …”
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    Visual loss and presumed pseudoxanthoma elasticum confirmed with genetic analysis but not with skin examination and biopsies
  2. 1202
    “…In this review (Part 1), we present an overview of research conducted on some fruits (grapefruit, cranberries, pomegranate, guava, pineapple, and mango) which are frequently consumed by humans, as well as the analysis of some phytochemicals extracted from fruits and yeasts which have demonstrated antigenotoxic capacity in various tests, including the Ames assay, sister chromatid exchange, chromosomal aberrations, micronucleus and comet assay.…”
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    Evidence of Some Natural Products with Antigenotoxic Effects. Part 1: Fruits and Polysaccharides
  3. 1203
    “…LSM, 3D-SIM, proximity ligation assay (PLA) and co-immunoprecipitation methods applied in combination with selective depletion of β- or γ-cytoplasmic actins revealed a selective interaction between microtubules and γ-, but not β-cytoplasmic actin via the microtubule +TIPs protein EB1. EB1-positive comet distribution analysis and quantification have shown more effective microtubule growth in the absence of β-actin. …”
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    Interaction of microtubules with the actin cytoskeleton via cross-talk of EB1-containing +TIPs and γ-actin in epithelial cells
  4. 1204
    por Sourakov, Andrei
    Publicado 2017
    “…The resulting aberrations are dubbed ‘Black Eye’ and ‘Comet Eye.’ Other known aberrations of Automeris io eyespots are summarized, illustrated, and named.…”
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    Giving eyespots a shiner: Pharmacologic manipulation of the Io moth wing pattern
  5. 1205
    “…Mitochondrial membrane potential was evaluated using Rhodamine-123 staining; the % apoptosis by Hoechst staining and acridine orange staining; DNA damage was measured by comet assay. The levels of p53, Bax, Bcl-xL, Bcl-2, Cytochrome c, Caspase-9 and Caspase-3 expression in HaCaT cells were analyzed by western blotting and RT-PCR. …”
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    Juglans regia L. protects against UVB induced apoptosis in human epidermal keratinocytes
  6. 1206
    Publicado 2013
    “…DNA damage was detected by single-cell gel electrophoresis (comet assay). RESULTS: TEM revealed that SiO2 nanoparticles with different sizes can be uptaken by cells and be localized in the cytoplasm and the nucleus. …”
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    纳米二氧化硅在人支气管上皮细胞内的亚细胞分布和遗传毒性
  7. 1207
    por Fang, Hao, Cui, Yibin, Wang, Zhuang, Wang, Se
    Publicado 2018
    “…In addition, genotoxicity was assessed by examining DNA damage in mouse liver and sperm via the comet assay, and transmission electron microscopy (TEM) was used for direct visual observations of mitochondrial damage in the liver. …”
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    Toxicological assessment of multi-walled carbon nanotubes combined with nonylphenol in male mice
  8. 1208
    “…To exclude any potential toxic effects of the oil on human dermal fibroblasts, the MTT test (methyl thiazolyl tetrazolium) and COMET assay (single-cell gel electrophoresis) were performed. …”
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    Novel Gel Formulations as Topical Carriers for the Essential Oil of Bidens tripartita for the Treatment of Candidiasis
  9. 1209
    por Hu, Xiaohua, Mullins, R. Dyche
    Publicado 2019
    “…Upon starvation, JMY shifts to motile, LC3-containing membranes that move on actin comet tails. LC3 enhances JMY’s de novo actin nucleation activity via a cryptic actin-binding sequence near JMY’s N terminus, and STRAP inhibits JMY’s ability to nucleate actin and activate the Arp2/3 complex. …”
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    LC3 and STRAP regulate actin filament assembly by JMY during autophagosome formation
  10. 1210
    “…The occurrence of karyolysis showed significant changes in this group as well. The comet assay data revealed genetic damage in peripheral blood cells for all groups of smokers. …”
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    Genomic Instability in Peripheral Blood and Buccal Mucosal Cells of Marijuana Smokers: The Impact of Tobacco Smoke
  11. 1211
    “…The purpose of this study was to compare the potential radio-sensitization effects of two different sized GNPs (3.9 and 37.4 nm) fabricated and examined in vitro in Lewis lung carcinoma (LLC) as a model of non-small cell lung cancer through use of comet and clonogenic assays. After treatment with 2Gy X-ray irradiation, both particle sizes demonstrated increased DNA damage when compared to treatment with particles only and radiation alone. …”
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    Gold Nanoparticles Radio-Sensitize and Reduce Cell Survival in Lewis Lung Carcinoma
  12. 1212
    por Salisbury, Laura
    Publicado 2022
    “…I include analyses of the anxious textuality of Don DeLillo’s The Silence and Saidiya Hartman’s reworking of W. E. B. Du Bois’s ‘The Comet’ to demonstrate how doomscrolling emerges from a moment when trust is anxiously fractured, but how it works, nevertheless, to witness what gets to count when time is felt to be coming to an end.…”
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    On not being able to read: doomscrolling and anxiety in pandemic times
  13. 1213
    “…The genotoxicity was investigated using a comet assay, and the mutagenicity was examined using micronucleus (MN) and erythrocytic nuclear abnormalities (ENAs) assays. …”
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    Investigation of genotoxicity, mutagenicity, and cytotoxicity in erythrocytes of Nile tilapia (Oreochromis niloticus) after fluoxetine exposure
  14. 1214
    “…The inhibitors of histone deacetylases (HDACis) exhibit selective antiproliferative effects against transformed and tumor cells and could enhance tumor cell sensitivity to genotoxic agents, which is partly attributed to their ability to interfere with DDR. Using the comet assay and host-cell reactivation of transcription, as well as γH2AX staining, we have shown that sodium butyrate inhibited DNA double-strand break (DSB) repair of both endo- and exogenous DNA in transformed but not in normal cells. …”
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    HDAC Inhibitor Sodium Butyrate Attenuates the DNA Repair in Transformed but Not in Normal Fibroblasts
  15. 1215
    por Vatan, Özgür
    Publicado 2022
    “…The cytotoxic and genotoxic potentials of Fe-Ni ANPs were investigated by XTT, clonogenic, comet, and GammaH2AX analyses using Beas-2B cells. …”
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    Evaluation of In Vitro Cytotoxic, Genotoxic, Apoptotic, and Cell Cycle Arrest Potential of Iron–Nickel Alloy Nanoparticles
  16. 1216
    “…Cytotoxicity, cell survival (5 days), cell cycle kinetics (flow cytometry), genotoxicity (comet assay), and gene (TP53, BAX, and BCL2) expression profiles were evaluated using reverse-transcriptase quantitative polymerase chain reaction. …”
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    In vitro toxicogenomic activity of an MTA/salicylate-based endodontic sealer
  17. 1217
    “…Five fungicides—Amistar(®) (250 g·L(−1) azoxystrobin), Filan(®) (500 g·kg(−1) boscalid), Comet(®) 200 (200 g·L(−1) pyraclostrobin), Imtrex(®) (62.5 g·L(−1) fluxapyroxad), Poraz(®) (450 g·L(−1) prochloraz)—were investigated for their potential as selective inhibitors in culture media for the isolation of F. graminearum from soil and plant material. …”
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    Screening of Fungicides and Comparison of Selective Media for Isolation of Fusarium graminearum from Soil and Plant Material
  18. 1218
    “…IMPORTANCE: In the previously reported Comparative Enzyme Replacement Trial With neoGAA Versus rhGAA (COMET) trial, avalglucosidase alfa treatment for 49 weeks showed clinically meaningful improvements in upright forced vital capacity (FVC) percent predicted and 6-minute walk test (6MWT) compared with alglucosidase alfa. …”
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    Efficacy and Safety of Avalglucosidase Alfa in Patients With Late-Onset Pompe Disease After 97 Weeks: A Phase 3 Randomized Clinical Trial
  19. 1219
    “…Neutral comet assay and immunofluorescence staining was used to measure DNA double strand breaks. …”
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    Cysteine depletion sensitizes prostate cancer cells to agents that enhance DNA damage and to immune checkpoint inhibition
  20. 1220
    “…Therefore, it has become necessary to rely on using the comet assay, which is not necessarily specific for 8-oxo-dGuo. …”
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    Analysis of 7,8-Dihydro-8-oxo-2′-deoxyguanosine in Cellular DNA during Oxidative Stress
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