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  1. 1281
    “…Overexpression of Hsp70 protein suggests alar induced subcellular molecular stress and comet assay validates genotoxicity in the form of DNA damage in the treated larvae. …”
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    Exploration of teratogenic and genotoxic effects of fruit ripening retardant Alar (Daminozide) on model organism Drosophila melanogaster
  2. 1282
    “…The DNA protective role was further tested by the single-cell gel electrophoresis (COMET) assay and by Fenton’s reagent causing double-strand breaks on the closed circular high copy pUC19 plasmid isolated from Escherichia coli. …”
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    Chemical Composition and Biological Activity of Allium cepa L. and Allium × cornutum (Clementi ex Visiani 1842) Methanolic Extracts
  3. 1283
    “…The cultures were treated with essential oil (EO) of Schinus molle L. and subsequently subjected to genotoxic analysis (comet assay), mutagenic analysis (micronucleus frequency and chromosomal aberration), and cytotoxic (cell viability) and functional parameters (interleukins secretions). …”
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    Immunotoxicological Evaluation of Schinus molle L. (Anacardiaceae) Essential Oil in Lymphocytes and Macrophages
  4. 1284
    “…Cell viability of leukocytes and an alkaline comet assay were performed to evaluate the cytotoxicity. …”
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    Synthesis and Biological Evaluation of Hydrazone Derivatives as Antifungal Agents
  5. 1285
    “…In addition, an analysis of some phytochemicals extracted from those vegetables and the analysis of a resin (propolis),whose antigenotoxic power has been demonstrated in various tests, including the Ames assay, sister chromatid exchange, chromosomal aberrations, micronucleus, and comet assay, was also performed.…”
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    Evidence of Some Natural Products with Antigenotoxic Effects. Part 2: Plants, Vegetables, and Natural Resin
  6. 1286
    “…In addition, the total anti-oxidant power of plasma and the DNA damage were measured by FRAP test and COMET assay, respectively. LPS increased the COX2 expression, the TNF-α production and the DNA damage. …”
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    Hydroxytyrosol Exerts Anti-Inflammatory and Anti-Oxidant Activities in a Mouse Model of Systemic Inflammation
  7. 1287
    “…A 48 h MTT assay indicated that tributyltin isothiocyanate (TBT-ITC) is more cytotoxic than triphenyltin isothiocyanate (TPT-ITC) in MCF 7 cells, and the same trend was observed in the MDA-MB-231 cell line. A comet assay revealed the presence of both crosslinks and increasing DNA damage levels after the 17 h treatment with both derivatives. …”
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    Genotoxic Effects of Tributyltin and Triphenyltin Isothiocyanates, Cognate RXR Ligands: Comparison in Human Breast Carcinoma MCF 7 and MDA-MB-231 Cells
  8. 1288
    “…Different biochemical analysis (serum liver and kidney enzymes level, cholesterol and Glucose levels) were evaluated. DNA damage using comet assay and histopathological examination of different body organs were also screened. …”
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    Investigating the potential protective effects of natural product quercetin against imidacloprid-induced biochemical toxicity and DNA damage in adults rats
  9. 1289
    “…We showed examples of the tool’s use with fluorescence data and DNA-damage related Comet tail quantitation. This FairSubset tool and the method to retain distribution information at the single-datum level may be considered for standardized use in fair publishing practices.…”
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    FairSubset: A tool to choose representative subsets of data for use with replicates or groups of different sample sizes
  10. 1290
    “…Caloric restriction and also the HCLP diet lead to ca. 30% weight loss, which is paralleled by decreased DNA damage (“comet” formation) and oxidative damage of purines in inner organs, additionally the activity of nucleotide excision repair increased. …”
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    Impact of Weight Loss Strategies on Obesity‐Induced DNA Damage
  11. 1291
    “…This study analyses the impact of CAPE on the cytotoxic (MTT assay), genotoxic (comet assay) and proapoptotic (caspase-3/7 activity) potential of irinotecan and its metabolite SN-38 in cultures of gastrointestinal neoplastic cells (HCT116, HT29, AGS). …”
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    Antagonistic Effects of CAPE (a Component of Propolis) on the Cytotoxicity and Genotoxicity of Irinotecan and SN38 in Human Gastrointestinal Cancer Cells In Vitro
  12. 1292
    “…Low energy ion measurements in the vicinity of a comet have provided us with important information about the planet’s evolution. …”
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    Performance of a Low Energy Ion Source with Carbon Nanotube Electron Emitters under the Influence of Various Operating Gases
  13. 1293
    “…Methods: HUVECs were treated with compounds induce DNA single-strand breaks (SSBs) using the comet assay. Oxidative DNA damage was detected using endonuclease III (Nth) or human 8 oxoguanine DNA glycosylase (hOOG1). …”
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    The Protective Effect of Dabigatran and Rivaroxaban on DNA Oxidative Changes in a Model of Vascular Endothelial Damage with Oxidized Cholesterol
  14. 1294
    “…Our results indicated a concentration-dependent enhancement of reactive oxygen species measured through flow cytometry and DNA damage evaluated via the comet assay. Additionally, it induced apoptosis in all tested concentrations. …”
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    Benomyl, a benzimidazole fungicide, induces oxidative stress and apoptosis in neural cells
  15. 1295
    por Wójcik, Ewa, Sokół, Agnieszka
    Publicado 2020
    “…Helpful tests for assessment of instabilities include the sister chromatid exchange assay, identification of fragile sites, the bleomycin assay and the comet assay. These techniques can be used to assess and compare the chromosome stability of individual breeds of animals. …”
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    Assessment of chromosome stability in boars
  16. 1296
    “…Oxidative damage, premature interruption of the apoptotic process and defects in DNA compaction during spermatogenesis are the main mechanisms that cause DNA breaks in sperm. The two-tailed Comet assay is the only technique that can differentiate single- (SSBs) from double- (DSBs) strand DNA breaks. …”
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    The Impact of Single- and Double-Strand DNA Breaks in Human Spermatozoa on Assisted Reproduction
  17. 1297
    “…Surprisingly, worms with a null mutation in PCH-2’s adapter protein, CMT-1, the ortholog of p31(comet), localize PCH-2 to meiotic chromosomes, exhibit non-homologous synapsis and lose crossover assurance. …”
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    PCH-2 collaborates with CMT-1 to proofread meiotic homolog interactions
  18. 1298
    “…Water and sediment samples were collected simultaneously for physicochemical and heavy metal analyses. The comet assay was performed as a biomarker of genotoxicity. …”
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    Genotoxic effect of heavy metals on Astyanax lacustris in an urban stream
  19. 1299
    por Onbasli, Dilsad, Yuvali, Gokcen
    Publicado 2021
    “…While the antioxidant activity of the extract was evaluated by DPPH, metal chelating, plasma lipid peroxidation and total phenolic content, the antigenotoxicity and cytotoxicity were established by Comet test and the WST-1 Cell proliferation assay kit respectively. …”
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    In vitro medicinal potentials of Bryum capillare, a moss sample, from Turkey
  20. 1300
    “…None of the NFCs induced genotoxic effects, as evaluated by the alkaline comet assay and the cytokinesis-block micronucleus assay. …”
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    Role of Surface Chemistry in the In Vitro Lung Response to Nanofibrillated Cellulose
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