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  1. 1301
    “…In addition, the in vitro standard and enzyme-modified (human 8-oxoguanine DNA glycosylase 1 (hOGG), endonuclease III (EndoIII), human alkyladenine DNA glycosylase (hAAG)) comet assay (S9−/S9+) was conducted in order to assess the potential premutagenic lesions in TK6 cells. …”
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    In Vitro Genotoxicity Assessment of Functional Ingredients: Betaine, Choline, and Taurine
  2. 1302
    “…These in vitro results were ascertained by in vivo experiments, which also supported the free radical-mediated oxidative stress. The comet assay confirmed the oxidative stress that leads to DNA damage. …”
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    Bioactive Tryptophan-Based Copper Complex with Auxiliary β-Carboline Spectacle Potential on Human Breast Cancer Cells: In Vitro and In Vivo Studies
  3. 1303
    “…Its imaging characteristics can be variable, but they usually exhibit comet tail artifacts on ultrasound. In equivocal cases, claw sign on CT scan is diagnostic to confirm the site. …”
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    Thyroid “claw sign” a useful diagnostic marker in the outsized lesions of isthmus: A large colloid cyst.
  4. 1304
    “…CAPP treatment caused the increased expression of genes for heat shock proteins HSP101 and HSP70 in the first two days after sowing. Using comet assay it was observed that shorter treatment times (30–120 s) did not cause DNA damage. …”
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    Cold Atmospheric Pressure Plasma Treatment of Maize Grains—Induction of Growth, Enzyme Activities and Heat Shock Proteins
  5. 1305
    “…While gel electrophoresis was used to determine DNA cleavage activity and production of reactive oxygen species (ROS), the Comet assay was used to determine induced genomic DNA damage. …”
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    Understanding the Potential In Vitro Modes of Action of Bis(β‐diketonato) Oxovanadium(IV) Complexes
  6. 1306
    por Liehr, Thomas
    Publicado 2021
    “…Here especially highlighted variations of FISH are molecular combing, chromosome orientation-FISH (CO-FISH), telomere-FISH, parental origin determination FISH (POD-FISH), FISH to resolve the nuclear architecture, multicolor-FISH (mFISH) approaches, among other applied in chromoanagenesis studies, Comet-FISH, and CRISPR-mediated FISH-applications. …”
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    Molecular Cytogenetics in the Era of Chromosomics and Cytogenomic Approaches
  7. 1307
    por Song, Jin Ah, Choi, Cheol Young
    Publicado 2021
    “…The H(2)O(2) and LPO levels at each SW increased significantly with time. A comet assay also revealed that changes in salinity increased the rate of nuclear DNA damage in all the salinity groups. …”
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    Temporal Changes in Physiological Responses of Bay Scallop: Performance of Antioxidant Mechanism in Argopecten irradians in Response to Sudden Changes in Habitat Salinity
  8. 1308
    “…In this study, the toxicity of the five goldenseal alkaloid constituents was characterized, and their toxic potencies were compared. As measured by the Comet assay and the expression of γ-H2A.X, berberine, followed by palmatine, appeared to be the most potent DNA damage inducer in human hepatoma HepG2 cells. …”
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    Mechanism study of goldenseal-associated DNA damage
  9. 1309
    “…The aim of this study was to evaluate the genotoxic effects of Al(2)O(3), Fe(2)O(3), and Cu nanoparticles with chromosomal aberration (CA), micronucleus (MN), and comet assays on the bone marrow of male BALB/c mice. …”
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    Genotoxicity of aluminium oxide, iron oxide, and copper nanoparticles in mouse bone marrow cells
  10. 1310
    “…As a complement, the standard and Fpg-modified comet assays for the evaluation of strand breaks, alkali labile sites and oxidative DNA damage were also performed in TK6 cells. …”
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    In Vitro Genotoxicity Evaluation of an Antiseptic Formulation Containing Kaolin and Silver Nanoparticles
  11. 1311
    “…The first stage of the research was to determine genotoxicity using the comet test, which confirmed the safety of A. arborescens. …”
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    Aloe arborescens: In Vitro Screening of Genotoxicity, Effective Inhibition of Enzyme Characteristics for Disease Etiology, and Microbiological Activity
  12. 1312
    “…The effect of the GNPs on cell growth in real-time was determined by using xCELLigence, followed by a comet assay for genotoxicity determination. The HepG2 cells experienced genotoxicity for all GNP ligands; however, they were able to initiate repair mechanisms and recover DNA damage, except for two functionalization chemistries.…”
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    A Comparison of the Genotoxic Effects of Gold Nanoparticles Functionalized with Seven Different Ligands in Cultured Human Hepatocellular Carcinoma Cells
  13. 1313
    “…Most of the evaluations were performed in vitro using the comet assay (detecting DNA damage). The micronucleus assay (detecting chromosome damage) was the most used validated assay, whereas only two publications reported results on mammalian gene mutations. …”
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    Genotoxicity of Graphene-Based Materials
  14. 1314
    “…The aim of the present study was to investigate whether weekly exposure to gamma rays causes a persistent increase in the number of radioresistant leukocytes in mice in vivo. Using the comet assay, 1 Gy radiation exposure decreased the percentage of leukocytes with less than 5% DNA in the tail (<5% DNAT), and we propose that radioresistance induction might increase the number of cells with <5% DNAT after radiation exposure. …”
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    Induction and assessment of persistent radioresistance in murine leukocytes in vivo
  15. 1315
    “…Oxidative stress, DNA damage, cell membrane integrity, serum lactate dehydrogenase, and cytotoxicity, were investigated by Ferric Reducing Antioxidant Potential (FRAP) test, alkaline comet assay, measuring serum lactate dehydrogenase (LDH), Hoechst staining and flow cytometry with propidium iodide (PI) respectively. …”
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    Paraquat induced oxidative stress, DNA damage, and cytotoxicity in lymphocytes
  16. 1316
    “…The addition of CORM-3 to human colorectal cancer cells leads to strand breaks in the DNA, as assessed by the alkaline comet assay. DNA damage is inhibited by growth media containing amino acids, which bind to extracellular Ru and prevent its entry into cells. …”
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    CORM-3 induces DNA damage through Ru(II) binding to DNA
  17. 1317
    “…Genotoxicity and mutagenicity studies were performed by comet, micronucleus, and Ames tests on Salmonella typhimurium strains, which showed cellular safety and nonmutagenicity of menaquinone-7. …”
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    Safety assessment of menaquinone-7 for use in human nutrition
  18. 1318
    “…There is some evidence that oxidative DNA damage is increased following SCI, mainly using comet assays and immunohistochemistry. However, there is great variability in the timing and magnitude of its appearance, likely due to differences in experimental models, measurement techniques, and the rigor of the approach. …”
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    Oxidative DNA Damage in the Pathophysiology of Spinal Cord Injury: Seems Obvious, but Where Is the Evidence?
  19. 1319
    “…The limitations and variability of these tests comet the investigator to propose combining them in diagnostic algorithms to produce more accurate tools. …”
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    Nonalcoholic Fatty Liver Disease—A Concise Review of Noninvasive Tests and Biomarkers
  20. 1320
    “…We demonstrate the validity of CE-BART on the VisualCOMET and AVSD benchmarks. CE-BART achieved SOTA performance on both benchmarks, while an extensive ablation study and qualitative analysis demonstrated the performance gain and improved interpretability.…”
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    CE-BART: Cause-and-Effect BART for Visual Commonsense Generation
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