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  1. 1461
    “…In the wet lab, we remarkably found that HG results in severe DNA damage to TNBC cells as observed using the comet assay. In addition, several DDR genes were confirmed to be upregulated using qPCR analysis in the same cell line. …”
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    High Glucose Increases DNA Damage and Elevates the Expression of Multiple DDR Genes
  2. 1462
    “…Growth curves were obtained, and the genotoxic effect was evaluated with a comet assay. The results indicate that initially, an induction of the apoptotic process is observable, but this is subsequently reversed by Bcl2. …”
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    Particle Debris Generated from Passenger Tires Induces Morphological and Gene Expression Alterations in the Macrophages Cell Line RAW 264.7
  3. 1463
    por Gordin, Michael D
    Publicado 2012
    “…Properly analyzed, the collective mythological and religious writings of humanity reveal that around 1500 BC, a comet swept perilously close to Earth, triggering widespread natural disasters and threatening the destruction of all life before settling into solar orbit as Venus, our nearest planetary neighbor.   …”
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    The pseudoscience wars: Immanuel Velikovsky and the birth of the modern fringe
  4. 1464
    “…Quantification of DNA damage by a comet assay revealed that the Klotho knockdown significantly increased the amount of DNA damage immediately after IR, suggesting that Klotho protects chromosomal DNA from the induction of damage, rather than facilitating DNA repair. …”
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    Klotho protects chromosomal DNA from radiation-induced damage
  5. 1465
    por Kim, Jiwan, Choi, Jinhee
    Publicado 2023
    “…The genotoxicity and epigenotoxicity of CMIT/MIT were examined using a comet assay and global DNA methylation measurements. …”
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    Trans- and Multigenerational Effects of Isothiazolinone Biocide CMIT/MIT on Genotoxicity and Epigenotoxicity in Daphnia magna
  6. 1466
    “…We used cell cycle assay, lipid peroxidation assay, comet assay, and apoptosis assay to unearth the potential causes. …”
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    Pronounced Enhancement in Radiosensitization of Esophagus Cancer Cultivated in Docosahexaenoic Acid via the PPAR -γ Activation
  7. 1467
    por Cheng, Zhiyuan, Song, Ge, Fu, Yan
    Publicado 2022
    “…Currently, the search engines supported by PTMiner include pFind, MSFragger, MaxQuant, Comet, MS-GF + and SEQUEST.…”
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    A protocol of using PTMiner for quality control and localization of protein modifications identified by open or closed search of tandem mass spectra
  8. 1468
    “…The level of reactive oxygen species in NSCs was significantly elevated and the cell membrane was damaged, causing the release of intracellular lactate dehydrogenase (p < 0.05). The comet experiment and γ-H2AX immunofluorescence assay showed that AFB(1) caused significant DNA damage to NSCs (p < 0.05). …”
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    A Novel Multicellular Placental Barrier Model to Investigate the Effect of Maternal Aflatoxin B(1) Exposure on Fetal-Side Neural Stem Cells
  9. 1469
    “…DNA damage in the cells was immediately assessed quantitatively using the CometScore™ software. RESULTS: Comets were found in cataractous LECs. …”
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    In vitro assessment of the severity of deoxyribonucleic acid damage in different types of cataracts directly in lens epithelial cells
  10. 1470
    “…To assess the anticancer activity of this combination, we analyzed cell viability (MTT assay), oxidative stress (CM-H(2)DCFDA), autophagy (fluorescence), DNA damage (comet assay), and protein expression (Western blot). …”
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    Sulforaphane Combined with Vitamin D Induces Cytotoxicity Mediated by Oxidative Stress, DNA Damage, Autophagy, and JNK/MAPK Pathway Modulation in Human Prostate Tumor Cells
  11. 1471
    “…The genotoxic effect was evaluated by Comet Assay. RESULTS: The oxidative stress biomarkers; Disulfide, TOS, MPO, oxidative stress index, and IL-1β, IL-6, and TNF-α levels of inflammation biomarkers and the DNA damage in COVID-19 patients were increased (p<0.001), and the levels of TAS, TT, and NT In COVID-19 patients were decreased (p<0.001). …”
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    Oxidative stress, DNA damage, and inflammation in COVID-19 patients
  12. 1472
    “…Next, we assessed the antioxidant potential of Lactobacilli and role in bile injury repair: we measured bile-induced DNA damage using the ROS marker 8-oxo guanine and COMET assay. Lactobacillus addition after bile injury accelerated repair of bile-induced DNA damage through recruitment of pH2AX/RAD51 and reduced NFκB-associated inflammation in esophageal cells. …”
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    Lactobacillus sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease
  13. 1473
    “…DNA damage was analysed using comet assay while the micronucleus test was used for assessing nuclear abnormalities. …”
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    Mutagenicity and genotoxicity in juvenile African catfish, Clarias gariepinus exposed to formulations of glyphosate and paraquat
  14. 1474
    “…Whole blood and plasma were analyzed for DNA damage using a comet assay with 3 different treatments (lysis buffer, H(2)O(2), and the lesion-specific enzyme formamidopyrimidine DNA glycosylase (FPG)) as well as for the oxidative stress markers protein carbonyls (PC), unconjugated bilirubin (UCB), and ferric reducing antioxidant power (FRAP). …”
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    Effect of Repeated Bolus and Continuous Glucose Infusion on DNA Damage and Oxidative Stress Biomarkers in Healthy Male Volunteers
  15. 1475
    “…Methods: We performed a 72-window LUS in 75 patients presenting to the outpatient rheumatology clinic and describe the abnormalities (presence of B-lines (vertical comet-tail artefacts), pleural abnormalities, pleural effusions, and subpleural nodules) on lung ultrasound. …”
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    Ultrasonographic Presentation and Anatomic Distribution of Lung Involvement in Patients with Rheumatoid Arthritis
  16. 1476
    “…The influence of HRE on genome integrity and the cell cycle was also studied via comet assay and flow cytometry. Our findings demonstrate that HREs can effectively modulate the cellular response to genotoxic and oxidative stress within the first two hours following exposure, thereby reducing the severity of such stress. …”
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    Haberlea rhodopensis Extract Tunes the Cellular Response to Stress by Modulating DNA Damage, Redox Components, and Gene Expression
  17. 1477
    “…At the periphery of the lesion, unstable vitiligo usually shows up as a diffuse border, trichrome pattern, micro-Koebner/comet tail phenomenon, satellite lesions, or a tapioca sago pattern. …”
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    Dermatoscopic Patterns in Vitiligo
  18. 1478
    “…Furthermore, the defective SSBR observed in S phase of RAD18−/− cells was also demonstrated by alkaline comet assay.…”
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    Human RAD18 is involved in S phase-specific single-strand break repair without PCNA monoubiquitination
  19. 1479
    “…Interestingly, those constructs similarly affect other actin-based phenomenons, such as InlB-induced membrane ruffling or Listeria comet tail formations. Thus, our data provide evidence for a control of phagocytosis by both activation and deactivation of cofilin. …”
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    A role for cofilin and LIM kinase in Listeria-induced phagocytosis
  20. 1480
    “…The Rad51 focus formation and comet assays revealed that the DNA repair function of BRCA1 was impaired when the PP1-binding motif was mutated. …”
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    A PP1-binding motif present in BRCA1 plays a role in its DNA repair function
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