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  1. 1561
    “…Genotoxicity was assessed in both male and female mice by various assay systems, such as comet assay, chromosomal aberrations and micronuclei assay, which detect different abnormalities. …”
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    Evaluation of the in vivo genotoxicity of liposomal formulation for delivering anticancer estrogenic derivative (ESC8) in a mouse model
  2. 1562
    “…Extent of DNA damage in leucocytes was assayed by comet assay. RESULTS: Pulmonary function parameters, FVC, FEV(1), PEFR, and MVV measured in workers were significantly (p<0.05) lower than those observed in the comparison group. …”
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    Pulmonary Functions, Oxidative Stress and DNA Damage in Workers of a Copper Processing Industry
  3. 1563
    “…The alterations in antioxidant enzymes’ activity (SOD, CAT, and GPX), hepatic enzymes’ activity (ALT, AST and ALP), DNA damage (measured by comet assay and cellProfiler software) and CYP1A gene expression in the fish liver were studied on the 1st, 3rd, 7th and 14th days. …”
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    Interactions of oxidative DNA damage and CYP1A gene expression with the liver enzymes in Klunzinger’s mullet exposed to benzo[a]pyrene
  4. 1564
    “…Cytotoxicity was evaluated with trypan blue vitality test, while genotoxic damage was performed by Comet Test, Diffusion Assay and RAPD-PCR for 48 and 72 exposure hours. …”
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    NPs-TiO(2) and Lincomycin Coexposure Induces DNA Damage in Cultured Human Amniotic Cells
  5. 1565
    “…Given the intended use in food for human consumption, and noting its potential presence at trace levels in finished products, a series of safety studies including in vitro Ames and chromosome aberration assays, in vivo mammalian erythrocyte micronucleus and alkaline comet assays, and a 90‐day rat oral toxicity study were conducted. …”
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    Safety evaluation of arabinase (arabinan endo‐1,5‐α‐L‐arabinanase) from Aspergillus tubingensis
  6. 1566
    “…To illuminate the signal pathway involved in the radioresistance and evaluate the potential for predicting NPC response to radiotherapy, we established the radioresistant NPC cell line (CNE2-RR) derived from NPC cell line CNE2 by gradually increased the radiation dose (total 60 Gy), and the radioresistance of CNE2-RR cells was evaluated by the colony formation, FCM and comet assays. Furthermore, comparison of established CNE2-RR cell line to parental cell line found the homologous recombination repair (HRR) proteins differences involved in NPC radioresistance. …”
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    The Homologous Recombination Repair Pathway is Associated with Resistance to Radiotherapy in Nasopharyngeal Carcinoma
  7. 1567
    por Foster, Harold D.
    Publicado 2007
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    Disaster Planning for Cosmic Impacts: Progress and Weaknesses
  8. 1568
    “…Objectives: To identify long-term trends in HIV-1 molecular epidemiology and antiretroviral drug resistance (ARV) among migrants followed up in Portugal Methods: 5177 patients were included between 2001 and 2017. Rega, Scuel, Comet, and jPHMM algorithms were used for subtyping. …”
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    Molecular Epidemiology of HIV-1 Infected Migrants Followed Up in Portugal: Trends between 2001–2017
  9. 1569
    “…The presence of the BI-04 strain reduced the intracellular oxidative stress and DNA damage incurred in the colon epithelial cells by BaP treatment due to the enhanced expression of antioxidant enzymes and metabolism-related enzymes (CYP1A1). The data from comet assay, qRT-PCR, and western blot analysis showed that the cytotoxic effects of BaP on colon epithelial cells were largely alleviated because the bifidobacterial strain could bind to this carcinogenic compound. …”
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    Potential of Inactivated Bifidobacterium Strain in Attenuating Benzo(A)Pyrene Exposure-Induced Damage in Colon Epithelial Cells In Vitro
  10. 1570
    “…The instrument COSIMA (COmetary Secondary Ion Mass Analyzer) onboard of the European Space Agency mission Rosetta collected and analyzed dust particles in the neighborhood of comet 67P/Churyumov‐Gerasimenko. The chemical composition of the particle surfaces was characterized by time‐of‐flight secondary ion mass spectrometry. …”
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    Composition of cometary particles collected during two periods of the Rosetta mission: multivariate evaluation of mass spectral data
  11. 1571
    “…All Ni exposures caused DNA strand breaks (comet assay), whereas no induction of micronuclei was observed. …”
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    Transcriptome Profiling and Toxicity Following Long-Term, Low Dose Exposure of Human Lung Cells to Ni and NiO Nanoparticles—Comparison with NiCl(2)
  12. 1572
    “…MATERIALS AND METHODS: Isolated peripheral blood lymphocytes from 62 painters and 62 unexposed subjects were analyzed by the modified high-throughput comet assay with the Fpg and AlkA enzymes. The categories used for the evaluation of the DNA damage were basal damage (without enzymes), oxidative and methylating damage. …”
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    Evaluación del daño oxidativo y por metilación del ADN de pintores expuestos ocupacionalmente a solventes orgánicos y pintura
  13. 1573
    “…Model calibration is attempted from clonogenic assay data (doses of 0–6 Gy) and from time-resolved comet assay data obtained within 6 h after irradiation with 6 Gy. …”
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    Holistic View on Cell Survival and DNA Damage: How Model-Based Data Analysis Supports Exploration of Dynamics in Biological Systems
  14. 1574
    “…This study explored the application oxidative stress, comet assay, and micronucleus assay for in situ aquatic laboratory studies using fish O. mossambicus for screening the ecomutagenic and genotoxic potential of environmental pollutants.…”
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    Exploration of Cadmium Dioxide Nanoparticles on Bioaccumulation, Oxidative Stress, and Carcinogenic Potential in Oreochromis mossambicus L.
  15. 1575
    “…Cell toxicity was analyzed using MTT and neutral red (NR) uptake assays and apoptosis induction was analyzed using comet assay and caspase-3 activity. Oxidative stress following Hottentotta schach crude venom treatment was analyzed using nitrite oxide (NO) determination assay, reduced glutathione (GSH) and catalase enzyme activity assays. …”
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    In-vitro Study of Hottentotta Schach Crude Venom Anticancer Effects on MCF-7 and Vero Cell Lines
  16. 1576
    “…Finally, the stronger checkpoint in germline precursor cells is regulated by CMT-1, the ortholog of p31(comet), which is required for both PCH-2′s localization to unattached kinetochores and its enrichment in germline precursor cells. …”
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    The conserved AAA-ATPase PCH-2 (TRIP13) regulates spindle checkpoint strength
  17. 1577
    “…DNA damage levels of peripheral blood (mononuclear) cells in 45 newly diagnosed and untreated cancer patients and in 35 healthy individuals were measured using Alkaline Comet Assay technique. RESULTS: The DNA damage observed in cancer patients was significantly higher than in healthy individuals. …”
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    Vitamin D level and endogenous DNA damage in patients with cancers in Duhok city, KRG-Iraq
  18. 1578
    “…The genetic toxicity, using the alkaline comet assay, was evaluated. The studied extracts inhibited the cell proliferation of all tested cancer cell lines with concentration dependent effect over time. …”
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    Potent Cytotoxicity of Four Cameroonian Plant Extracts on Different Cancer Cell Lines
  19. 1579
    “…Herein, human hepatocellular (HepG2) cells were treated with 100, 200, and 400 μM TCEP for 3 days to quantify hepatotoxicity by MTT, NRU, and comet assays. Apoptosis, mitochondrial membrane potential (ΔΨm), oxidative stress, and Ca(2+) influx were measured by flow cytometry. …”
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    Tris(2-chloroethyl) Phosphate (TCEP) Elicits Hepatotoxicity by Activating Human Cancer Pathway Genes in HepG2 Cells
  20. 1580
    “…The study used peripheral blood comet assay, indicating DM-mediated damage to DNA at all exposure levels in a time responsive manner. …”
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    Dimethoate Induces DNA Damage and Mitochondrial Dysfunction Triggering Apoptosis in Rat Bone-Marrow and Peripheral Blood Cells
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