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  1. 1761
    “…DNA primary damage was evaluated by Comet assay while chromosomal damage and cell proliferation were assessed by Cytome assay. …”
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    Suitability of a Cellulose-Based Nanomaterial for the Remediation of Heavy Metal Contaminated Freshwaters: A Case-Study Showing the Recovery of Cadmium Induced DNA Integrity Loss, Cell Proliferation Increase, Nuclear Morphology and Chromosomal Alterations on Dreissena polymorpha
  2. 1762
    “…The involvement of oxidative stress and cell cycle arrest in the DNA and chromosome damage induced by 0.4–20 µg mL(−1) Au@Ag NR were investigated by comet assay, γ-H2AX assay and micronucleus test. …”
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    Roles of ROS and cell cycle arrest in the genotoxicity induced by gold nanorod core/silver shell nanostructure
  3. 1763
    por Wang, Lijuan, Li, Shangbiao, Zhu, Xiaoxia
    Publicado 2020
    “…The radiosensitivity of the cells was detected by clone formation assay, EDU cell proliferation assay, neutral comet assay, and γ-H2AX immunofluorescence staining. …”
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    Construction of Radiation Surviving/Resistant Lung Cancer Cell Lines with Equidifferent Gradient Dose Irradiation
  4. 1764
    “…Cytotoxic as well as genotoxic effects of the labeling procedure were measured in labeled and unlabeled hASCs using the MTT assay, comet assay and chromosomal aberration test. Trilineage differentiation was performed to evaluate an impairment of the differentiation potential due to the particles. …”
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    Superparamagnetic Iron Oxide Particles (VSOPs) Show Genotoxic Effects but No Functional Impact on Human Adipose Tissue-Derived Stromal Cells (ASCs)
  5. 1765
    “…Here, we developed two NSCLC radioresistant (RR) cell lines (A549-RR and H1299-RR) and characterized their motility, cell cycle distribution, DNA damage, and CSC production using migration/invasion assays, flow cytometry, comet assays, and sphere formation, respectively. …”
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    β-Elemene enhances radiosensitivity in non-small-cell lung cancer by inhibiting epithelial–mesenchymal transition and cancer stem cell traits via Prx-1/NF-kB/iNOS signaling pathway
  6. 1766
    “…The formamidopyrimidine-DNA glycosylase (FPG)-modified alkaline comet assay in conjunction with reactive oxygen species (ROS) assay and glutathione (GSH)/glutathione (GSSG) assay suggests that YM155-mediated oxidative stress contributes to DNA damage. …”
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    Ym155 Induces Oxidative Stress-Mediated DNA Damage and Cell Cycle Arrest, and Causes Programmed Cell Death in Anaplastic Thyroid Cancer Cells
  7. 1767
    “…A total of 205 children were randomly selected to assess the DNA damage in buccal cells, employing the comet assay. Total PAHs measured in exposed and comparative schools varied, respectively, from 61.60 to 64.64 ng m(−3) and from 5.93 to 35.06 ng m(−3). …”
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    Exposure to Particulate PAHs on Potential Genotoxicity and Cancer Risk among School Children Living Near the Petrochemical Industry
  8. 1768
    “…The cytotoxicity was measured by XTT, LDH assays and Giemsa staining, whereas genotoxicity via comet assay. Changes in cell morphology were assessed by phase-contrast microscopy. …”
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    The Potential Role of Small-Molecule PERK Inhibitor LDN-0060609 in Primary Open-Angle Glaucoma Treatment
  9. 1769
    “…DNA damage in peripheral blood mononuclear cells was assessed by the comet assay in 49 older subjects participating in the study. …”
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    Association between Food Intake, Clinical and Metabolic Markers and DNA Damage in Older Subjects
  10. 1770
    “…DNA primary reversible damage was evaluated by means of the Comet assay. Chromosomal persistent damage was assessed on the basis of micronuclei frequency and nuclear abnormalities by means of the Micronucleus-Cytome assay. …”
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    Suitability of Nanoparticles to Face Benzo(a)pyrene-Induced Genetic and Chromosomal Damage in M. galloprovincialis. An In Vitro Approach
  11. 1771
    “…These results were in accordance with liver histology analysis, liver comet assay, and changes in serum levels of ALT, AST, and AP. …”
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    Effects of C60 Fullerene on Thioacetamide-Induced Rat Liver Toxicity and Gut Microbiome Changes
  12. 1772
    “…The chemoprotective effects of XN were investigated in vitro in the metabolically competent HepG2 cell line, analyzing its influence on AFB1-induced cytotoxicity using the MTS assay, genotoxicity using the comet and γH2AX assays, and cell cycle modulation using flow cytometry. …”
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    Chemoprotective Effects of Xanthohumol against the Carcinogenic Mycotoxin Aflatoxin B1
  13. 1773
    “…DNA damage in leaf and roots nuclei was evaluated by the comet assay. AgNPs of the size 22–25 nm at concentrations higher than 50 mg·L(−1) significantly increased the tail moments (TM) values in leaf nuclei compared to the negative control. …”
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    Genomic Damage Induced in Nicotiana tabacum L. Plants by Colloidal Solution with Silver and Gold Nanoparticles
  14. 1774
    “…Then we discuss the reliability of endpoint assays, such as the comet assay, the most favored assessment technique because of its versatility to measure low levels of DNA strand breakage, and the micronucleus assay, which is complementary to the former because of its greater ability to detect chromosomal DNA fragmentation. …”
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    Nanoparticles: Weighing the Pros and Cons from an Eco-genotoxicological Perspective
  15. 1775
    “…The cytotoxic potential (MTT test) of single and combined STC and 5-M-STC, the nature of their interaction (additivity, antagonism, or synergy) and DNA damage level (alkaline comet assay) in HepG2 and A549 cells were also investigated. …”
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    Sterigmatocystin, 5-Methoxysterigmatocistin, and Their Combinations are Cytotoxic and Genotoxic to A549 and HepG2 Cells and Provoke Phosphorylation of Chk2, but not FANCD2 Checkpoint Proteins
  16. 1776
    “…Endogenous DNA damage levels were measured by comet assay. Immunophenotyping of leukocyte subpopulations was performed using flow cytometry. …”
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    Are Changes in the Percentage of Specific Leukocyte Subpopulations Associated with Endogenous DNA Damage Levels in Testicular Cancer Patients?
  17. 1777
    “…Genotoxicity was accessed through the Comet assay (alkaline version), acute and subacute oral toxicities were also evaluated. …”
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    Toxicity evaluation of Eleutherine plicata Herb. extracts and possible cell death mechanism
  18. 1778
    “…NFRFP exhibited a chemopreventive effect, in all protocols, with damage reduction (% DR) of 75% in the comet test. NFRFP reduced the incidence of aberrant crypt outbreaks by 49.36% in the post-treatment protocol. …”
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    The Use of Natural Fiber-Rich Food Product Is Safe and Reduces Aberrant Crypt Foci in a Pre-Clinical Model
  19. 1779
    “…DNA primary damage was investigated by the Comet assay; micronuclei frequency and nuclear morphological alterations were assessed by Cytome assay in mussels’ haemocytes. …”
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    Cellular Responses Induced by Zinc in Zebra Mussel Haemocytes. Loss of DNA Integrity as a Cellular Mechanism to Evaluate the Suitability of Nanocellulose-Based Materials in Nanoremediation
  20. 1780
    “…George Gershwin (1898–1937) was one of the most influential American composers of the 20(th) century. Likewise his swift, comet-like, career progress from a high school dropout to an iconic composer of the 20(th) century: “The man who said he had more notes in his head than he could write down in a hundred years died suddenly … in Hollywood”. …”
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    George Gershwin (1898–1937) – genius composer, malignant brain tumor patient. Malignant glioma: an irritating/stimulating element in triggering geniality?
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