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  1. 8881
    Publicado 1989
    “…Addition of D600 to fibers recovering from inactivation stopped further recovery, confirming preferential interaction of the drug with the inactivated state. A concerted model that assumed coupled transitions of independent drug-binding sites from the reprimed to the inactivated state adequately described the data obtained from reprimed fibers. …”
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    Block of contracture in skinned frog skeletal muscle fibers by calcium antagonists
  2. 8882
    “…We conclude that Nav1.9 channel, the molecular correlate of the NaN current, is potentiated by the concerted action of inflammatory mediators that may contribute to nociceptors' hyperexcitability during peripheral inflammation.…”
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    Inflammatory Mediators Increase Nav1.9 Current and Excitability in Nociceptors through a Coincident Detection Mechanism
  3. 8883
    Publicado 1991
    “…The COOH terminus of decay-accelerating factor (DAF) contains a signal that directs glycophosphatidylinositol (GPI) membrane anchor attachment in a process involving concerted proteolytic removal of 28 COOH- terminal residues. …”
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    A nonfunctional sequence converted to a signal for glycophosphatidylinositol membrane anchor attachment
  4. 8884
    “…In pyruvate kinase deficient strains the required equimolar ratio of the two lysine precursors oxaloacetate and pyruvate can be achieved through concerted action of the phosphotransferase system (PTS) and phosphoenolpyruvate carboxylase (PEPC), whereby a reduced amount of carbon may be lost as CO(2 )due to reduced flux into the tricarboxylic acid (TCA) cycle. …”
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    Metabolic responses to pyruvate kinase deletion in lysine producing Corynebacterium glutamicum
  5. 8885
    “…CONCLUSION: NF-κB globally regulates diverse gene programs that are organized in signal networks and pathways differing in cancer subsets with distinct p53 status. The concerted alterations in gene expression patterns reflect cross-talk among NF-κB and other pathways, which may provide a basis for molecular classifications and targeted therapeutics for heterogeneous subsets of head and neck or other cancers.…”
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    Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status
  6. 8886
    “…However, the poor reliability for several variables, particularly time-related events in the emergency department, indicates the need for concerted efforts to improve the quality of data collection. …”
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    Inter-rater reliability of data elements from a prototype of the Paul Coverdell National Acute Stroke Registry
  7. 8887
    “…CONCLUSION: The introduction of the ART programme has revealed both strengths and weaknesses of human resource development in one province of South Africa. Without concerted efforts to increase the supply of key health professionals, accompanied by changes in the deployment of health workers, the core goals of the ART programme – i.e. providing universal access to ART and strengthening the health system – will not be achieved.…”
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    Human resource development and antiretroviral treatment in Free State province, South Africa
  8. 8888
    por Richmond, Stewart J
    Publicado 2008
    “…The use of multiple control devices, including a copper bracelet, represents a concerted attempt to overcome methodological limitations associated with trials in this field. …”
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    Magnet therapy for the relief of pain and inflammation in rheumatoid arthritis (CAMBRA): A randomised placebo-controlled crossover trial
  9. 8889
    “…Following a resurgence in the 1990s, malaria transmission has been reduced considerably in Tajikistan as a result of concerted efforts by the government and international agencies. …”
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    History of malaria control in Tajikistan and rapid malaria appraisal in an agro-ecological setting
  10. 8890
    “…IPA also revealed biological relationships between these networks and known type 1 diabetes candidate genes. CONCLUSIONS—The concerted and synergistic alteration of histone methylation within the identified network in lymphocytes might have an effect on the etiology of type 1 diabetes and its complications. …”
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    Lymphocytes From Patients With Type 1 Diabetes Display a Distinct Profile of Chromatin Histone H3 Lysine 9 Dimethylation : An Epigenetic Study in Diabetes
  11. 8891
    “…Because tandemly-repeated, rDNA evolves under a balanced influence of selection and "concerted evolution", which homogenizes rDNA variants over the genome (through genomic turnover mechanisms) and the population (through sexuality). …”
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    The IGS-ETS in Bacillus (Insecta Phasmida): molecular characterization and the relevance of sex in ribosomal DNA evolution
  12. 8892
    “…To further analyze the global consequences of manipulating DGAT1 levels during seed development, a concerted transcriptome and metabolome analysis of transgenic B. napus prototypes was performed. …”
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    Transgenic increases in seed oil content are associated with the differential expression of novel Brassica-specific transcripts
  13. 8893
    “…CONCLUSIONS: Our data clarified the potential mechanism of PDGF signaling in the lens epithelial cells, in which concerted efforts of the upstream components of PDGF receptor kinase, Src-family kinases, PI3K, Rac, and Ras proteins are required. …”
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    Control of PDGF-induced reactive oxygen species (ROS) generation and signal transduction in human lens epithelial cells
  14. 8894
    “…Concerted depolarization and Ca(2+) rise during neuronal action potentials activate large-conductance Ca(2+)- and voltage-dependent K(+) (BK) channels, whose robust K(+) currents increase the rate of action potential repolarization. …”
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    Mechanism of Increased BK Channel Activation from a Channel Mutation that Causes Epilepsy
  15. 8895
    “…CONCLUSION: We have shown that, with concerted effort, a relatively complete inventory of mapped health services is possible with enormous potential for improving planning. …”
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    A spatial national health facility database for public health sector planning in Kenya in 2008
  16. 8896
    “…In parallel, for pairs of ancestral tRNAs with complementary anticodons, we present updated evidence of concerted complementarity of the second bases in the acceptor stems. …”
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    One ancestor for two codes viewed from the perspective of two complementary modes of tRNA aminoacylation
  17. 8897
    “…Surprisingly, this process could also be blocked by DIDS, suggesting the concerted action of Bax, VDAC and ceramide in the efflux of AIF from the mitochondrion. …”
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    Involvement of VDAC, Bax and Ceramides in the Efflux of AIF from Mitochondria during Curcumin-Induced Apoptosis
  18. 8898
    “…BACKGROUND: Single- and low- copy genes are less likely subject to concerted evolution, thus making themselves ideal tools for studying the origin and evolution of polyploid taxa. …”
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    Phylogeny and evolutionary history of Leymus (Triticeae; Poaceae) based on a single-copy nuclear gene encoding plastid acetyl-CoA carboxylase
  19. 8899
    por Cavalier-Smith, Thomas
    Publicado 2010
    “…According to the coevolutionary theory of eukaryote origins, the fundamental innovations were the concerted origins of the endomembrane system and cytoskeleton, subsequently recruited to form the cell nucleus and coevolving mitotic apparatus, with numerous genetic eukaryotic novelties inevitable consequences of this compartmentation and novel DNA segregation mechanism. …”
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    Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution
  20. 8900
    “…Despite increasing evaluation of single AP-2 isoforms in mammary tumors the functional role of concerted expression of multiple AP-2 isoforms in breast cancer remains to be elucidated. …”
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    Interference with Activator Protein-2 transcription factors leads to induction of apoptosis and an increase in chemo- and radiation-sensitivity in breast cancer cells
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