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  1. 8921
    “…Using this combined information, we identify a key subnetwork (functional module) of concerted changes in metabolic pathways, specific for de- and rehydration. …”
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    Integrated pathway modules using time-course metabolic profiles and EST data from Milnesium tardigradum
  2. 8922
    “…A tetrameric concatemer with only one high-affinity binding site still displayed high toxin sensitivity, suggesting that interaction with a single binding site prevented the concerted step required for channel opening. We propose a mechanism whereby gambierol anchors the channel’s gating machinery in the resting state, requiring more work from the VSD to open the channel. …”
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    The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state
  3. 8923
    “…RESULTS: A phylogenetic analysis of 77 NAT sequences from 38 vertebrate species retrieved from public genomic databases shows that NATs are phylogenetically unstable genes, characterized by frequent gene duplications and losses even among closely related species, and that concerted evolution only played a minor role in the patterns of sequence divergence. …”
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    Rapid birth-and-death evolution of the xenobiotic metabolizing NAT gene family in vertebrates with evidence of adaptive selection
  4. 8924
    “…Globalization of herbal medicine along with uncontrolled exploitative practices and lack of concerted conservation efforts, have pushed many of Nepal's medicinal plants to the verge of extinction. …”
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    Medicinal plants, traditional medicine, markets and management in far-west Nepal
  5. 8925
    “…BACKGROUND: As part of efforts to reduce maternal deaths in Karnataka state, India, there has been a concerted effort to increase institutional deliveries. …”
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    Availability and Distribution of Emergency Obstetric Care Services in Karnataka State, South India: Access and Equity Considerations
  6. 8926
    “…The steepest decline was observed after expansion of the safe abortion program to include midlevel providers, second trimester training, and medication abortion, highlighting the importance of concerted efforts to improve access. Other countries contemplating changes to abortion policy can draw on the evidence and implementation strategies observed in Nepal.…”
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    Effects of Abortion Legalization in Nepal, 2001–2010
  7. 8927
    por Hood, Leroy
    Publicado 2013
    “…Studying complex biological systems in a holistic rather than a “one gene or one protein” at a time approach requires the concerted effort of scientists from a wide variety of disciplines. …”
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    Systems Biology and P4 Medicine: Past, Present, and Future
  8. 8928
    “…Microscopic size and concerted convergences make morphological examination non-trivial and hamper phylogenetic reconstructions. …”
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    At the limits of a successful body plan – 3D microanatomy, histology and evolution of Helminthope (Mollusca: Heterobranchia: Rhodopemorpha), the most worm-like gastropod
  9. 8929
    “…The accompanying hard selective sweep is segmentally eclipsed as a consequence of recurrent ectopic gene conversion among HMA4 protein-coding sequences, resulting in their concerted evolution. Thus, HMA4 coding sequences exhibit a network-like genealogy and locally enhanced nucleotide sequence diversity within each copy, accompanied by lowered sequence divergence between paralogs in any given individual. …”
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    Hard Selective Sweep and Ectopic Gene Conversion in a Gene Cluster Affording Environmental Adaptation
  10. 8930
    “…Effective health system strengthening depends on inter-agency collaboration and country commitment along with concerted partnership among all the stakeholders working in the health system.…”
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    Global health initiative investments and health systems strengthening: a content analysis of global fund investments
  11. 8931
    “…The elevation of Ca(2+) is thought to be primarily driven by the concerted interplay of two alkalization-activated currents, a K(+) current (KSPER) composed of pore-forming subunits encoded by the Kcnu1 gene (also termed Slo3) and a Ca(2+) current arising from a family of CATSPER subunits. …”
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    Simultaneous knockout of Slo3 and CatSper1 abolishes all alkalization- and voltage-activated current in mouse spermatozoa
  12. 8932
    por Twumasi, Yaw A., Merem, Edmund C.
    Publicado 2006
    “…The project offers some recommendations as part of the conservation strategies. In spite of concerted efforts by managers to address the problems, results revel that the study area experienced some significant changes in its coastal environments. …”
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    GIS and Remote Sensing Applications in the Assessment of Change within a Coastal Environment in the Niger Delta Region of Nigeria
  13. 8933
    “…Mutagenesis within the ETON region revealed several hydrophobic and basic hot spot residues that appear to control STIM1 coupling to Orai1 in a concerted manner. Moreover, we identified two basic residues, which protrude into the elongated pore to redound to Orai1 gating. …”
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    The Extended Transmembrane Orai1 N-terminal (ETON) Region Combines Binding Interface and Gate for Orai1 Activation by STIM1
  14. 8934
    “…CONCLUSION: Un programme d'activité physique adapté à notre population d'hémodialysés et élaboré en concertation pluridisciplinaire (cardiologues, orthopédistes, rhumatologues, kinésithérapeutes) paraît intéressant dans le cadre d'une prise en charge globale du patient hémodialysé chronique.…”
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    Evaluation du niveau d'activité physique dans un service Marocain d'hémodialyse chronique
  15. 8935
    “…However, participants’ comments indicated a lack of concerted effort at the system level to address Aboriginal disadvantage in cancer outcomes.…”
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    Identifying barriers and improving communication between cancer service providers and Aboriginal patients and their families: the perspective of service providers
  16. 8936
    “…We conclude that our approach can transform rDNA sequence heterogeneity from a problem to a useful source of evolutionary information, enabling the estimation of highly accurate phylogenies of closely related organisms, and discuss how it could be extended to future studies of multilocus rDNA systems. [concerted evolution; genome hydridisation; phylogenetic analysis; ribosomal DNA; whole genome sequencing; yeast]…”
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    Ribosomal DNA Sequence Heterogeneity Reflects Intraspecies Phylogenies and Predicts Genome Structure in Two Contrasting Yeast Species
  17. 8937
    “…Of these, 40 pairs were either co-up- or co-downregulated indicating concerted 5p/3p regulation. The 5p/3p species of only 4 pairs were regulated in reverse directions. …”
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    Frequent Co-Expression of miRNA-5p and -3p Species and Cross-Targeting in Induced Pluripotent Stem Cells
  18. 8938
    “…Multivariable analysis demonstrated that smoking susceptibility was associated with smoking by exposure of adolescents to pro-tobacco advertisements (AOR [adjusted odds ratio] =2.49; 95% CI: 1.46–4.24), the teacher (2.45; 1.28–4.68), adolescents attending concerts/picnics (2.14; 1.13–4.04), and smoking by other family members/relatives (1.76; 1.05–2.95). …”
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    Correlates of smoking susceptibility among adolescents in a peri-urban area of Nepal: a population-based cross-sectional study in the Jhaukhel-Duwakot Health Demographic Surveillance Site
  19. 8939
    por Asefa, Anteneh, Teshome, Wondu
    Publicado 2014
    “…Patient's sex, perceived stigma, educational status and family size are significantly contributing for total delay. Therefore, a concerted effort should be taken in order to improve health seeking behavior of the community on TB and to reduce delays from seeking care after experiencing TB symptoms.…”
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    Total Delay in Treatment among Smear Positive Pulmonary Tuberculosis Patients in Five Primary Health Centers, Southern Ethiopia: A Cross Sectional Study
  20. 8940
    “…Community-based delivery of interventions to prevent and control malaria are effective strategies to improve coverage and access and reduce malaria burden, however, efforts should also be concerted to prevent over diagnosis and drug resistance.…”
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    Impact of community-based interventions for the prevention and control of malaria on intervention coverage and health outcomes for the prevention and control of malaria
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