“…CONCLUSION: Using CPA and gene expression analysis, we identified factors targeting MMP9 expression and/or function, namely CHEK1, CXCL10, ETS1, LEF1, and tissue inhibitor of metalloproteinase 1; altered mRNA expression of these could increase expression/activity of MMP9 in a concerted manner, thereby potentially impacting SS pathogenesis. …”
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“…These observations suggest that IR1—and, by extension, EBV—diversifies through both recombination and breakpoint repair, while concerted evolution of IR1 is driven by gene conversion of small regions. …”
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“…There is still need for a concerted effort focusing on reducing identified barriers, improve quality of care and provider counseling, and contextualize messaging behavior change communications and provider counseling.…”
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“…Comprehensive epidemiological studies are needed to identify contributors to chronic disease, including lifestyle behaviors. Concerted multi-level public health and clinical programs should be prioritized to help this population improve their health.…”
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“…Such restriction on the concerted efforts of HIV/AIDS-related NGOs in China would make achievement of the Sustainable Development Goals (SDGs) to foster stronger partnerships between the government and civil society difficult, which in turn hindering the realization of ending HIV/AIDS in the world by 2030.…”
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“…The changes call for more concerted efforts to address challenges such as insecticide resistance, environmental modifications or behavioural changes affecting the performance of current control measures.…”
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“…More importantly perhaps, the human and working capital built throughout the concertation process have the potential to be a fundamental cornerstone in dealing with more complex issues such as the chronically increasing level of underwater noise in whale habitats.…”
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“…Our findings highlight interplay between genes and environment on the expression of vocal behavior and suggest that closer interaction between taxonomists, ethologists, and molecular biologists should be rewarding in resolving the callicebine phylogeny. Such concerted efforts, in turn, will most likely generate valuable recommendations for the conservation of some endangered populations of titi monkeys, such as the vocally distinctive San Martin titi. …”
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“…For better integration of apps in clinical practice, concerted efforts are required among app developers, clinicians, and people with persistent pain in developing apps and evaluating for clinical efficacy.…”
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“…An intervention was more likely to be perceived as useful by AYAs when there was a concerted effort to involve AYAs and subject matter experts in the process of intervention design, as opposed to relying solely on the AYAs or the experts alone. …”
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“…CONCLUSIONS: In this study, over half of clinical trials initiated for rare diseases were either discontinued or not published 4 years after completion, resulting in large numbers of patients with rare diseases exposed to interventions that did not lead to informative findings. Concerted efforts are needed to ensure that participation of patients in rare disease trials advances scientific knowledge and treatments for rare diseases.…”
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“…METHODS: To evaluate the relevance of prematurely aged PolgA((D257A/D257A)) mice as a model for frailty and osteosarcopenia, we quantified the clinical mouse frailty index in PolgA((D257A/D257A)) and wild‐type littermates (PolgA((+/+)), WT) with age and concertedly assessed the quantity and quality of bone and muscle tissue. …”
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“…Conversely, subthermal collisions favor a different reaction mechanism: Ng chemi-ionization proceeds through another transition state [Ne*······Ng], a weakly bound diatomic-lengthened complex where Ne* reagent, behaving as a Na atom, loses its metastability and stimulates an electron ejection from M by a concerted emission–absorption of a “virtual” photon. …”
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“…This has resulted in a concerted global interest in open science uptake. Even so, barriers still exist. …”
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“…The benefits to patients and improvement in health services through a concerted regional effort are depicted. Some private patients are having recourse to external facilities for molecular profiling with no return of data for research. …”
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“…This study calls for a concerted effort aimed at determining the sociodemographic factors underlying this disturbing trend with the aim of developing preventative strategies. …”
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“…Genomic sequencing is needed to apportion risk to the workplace vs. the household/community. Concerted efforts are needed to mitigate risk factors due to ethnicity and lower level of education, even at this stage of the pandemic. …”
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“…These results constitute a step forward in the preparation of custom iridium-based materials crafted by excited-state engineering, which is achieved through the concerted effort of computational and synthetic chemistry along with electrochemistry and photochemistry.…”
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“…EXPÉRIENCE: Après une rapide concertation, la médecine du travail de l’Aisne a considéré que cette directive s’adressait aussi aux médecins du travail. …”
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“…The symptomatic cases accounted for 38.71% of the total cases, which was higher than that of the previous variants. After 6-week concerted efforts, Macau effectively controlled the outbreak, with an infection rate of 0.27%, which was much lower than many BA.5-attacked regions. …”
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