“…A noncompartmental PK analysis was conducted using preliminary data from 60 subjects up to Day 150 (900 observations). …”
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“…Hazard ratios were estimated from cox-proportional hazard models with facility random effects to account for clustering. We conducted stratified analyses by gender and baseline cardiovascular disease. …”
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“…Isolate identification and susceptibility testing were conducted by a central laboratory. Whole-genome sequencing was used to identify AME and β-lactamase genes. …”
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“…Liquid chromatography–mass spectrometry was performed using these extracted samples on an Agilent 1200 series HPLC and an AB Sciex Q-Trap 4000 mass spectrometer. Experiment conducted twice for confirmation. RESULTS: L-amB doses were well tolerated by the mice, except weight loss was seen in regimen E. …”
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“…BACKGROUND: In Argentina PCV13 was included in the National Vaccination Program in January 2012 for children <2 years old Since 1993 S. pneumoniae Surveillance Program (SIREVA II-OPS/WHO) was conducted in the National Reference Laboratory (NRL). …”
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“…However, it is unclear how particular microbial species influence the need for SBCs in GNB. METHODS: We conducted a prospective cohort study of inpatients at Duke with Staphylococcus aureus bacteremia (SAB) and GNB from 2002–2015. …”
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“…Isolate identification and susceptibility testing were conducted by a central laboratory. Whole-genome sequencing was used to identify AME and carbapenemase genes. …”
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“…BACKGROUND: In 2014, pneumococcal conjugate (PCV13) and polysaccharide (PPSV23) vaccines were recommended in series for all US adults ≥65 years. We conducted a case–control study to evaluate risk factors for invasive pneumococcal disease (IPD) among adults ≥65 years old. …”
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“…METHODS: A prospective observational cohort study was conducted, through the serotype surveillance program following the NIP implementation of 23-valent pneumococcal polysaccharide vaccine (PPV23) for elderly population (≥65 years) from 2013 to 2015. …”
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“…METHODS: A retrospective, cohort study was conducted at two pediatric hospitals in patients who received aminoglycosides from 1999 to 2016. …”
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“…Two separate studies were conducted, with oral VT-1598 treatment starting either 48 hours prior (prophylaxis) or 5 hours postinoculation (delayed), with 4 days of postinoculation dosing, and kidney fungal burden measured 1 day post last dose by both CFU and qPCR. …”
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“…Soon after, case reports of Guillain-Barre syndrome (GBS) following vaccination prompted subsequent studies, with a meta-analysis concluding that the attributable risk of GBS after MenACWY-D is unlikely to exceed 1 case per million vaccinations. We conducted a retrospective cohort study in the Vaccine Safety Datalink to assess the risk of 10 outcomes, including GBS, following MenACWY-D. …”
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“…METHODS: Two age cohorts (1 to < 4 years, and 6 to < 12 months, n = 120 per cohort) were enrolled in this ongoing double-blind, randomized, phase 2 dose-finding study conducted in Colombia and Panama. Children received one or two intramuscular doses of NoV formulations containing 15/15, 15/50, 50/50 or 50/150 μg of GI.1/GII.4c VLPs adjuvanted with 0.5 mg Al(OH)(3). …”
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“…TMB-301 was a 24-week, Phase 3 clinical trial conducted in 40 heavily treatment-experienced patients with multidrug-resistant (MDR) HIV-1 investigating the safety, efficacy and tolerability of IBA. …”
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“…We studied their prevalence, characteristics, outcome, and risk factors for poor outcome to better understand the clinical impact of suspected CNS infection in children. METHODS: We conducted a prospective study in the Children’s Hospital (HPDB) in the capital of Angola which attends 300 new patients daily. …”
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“…METHODS: The Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN) conducted active surveillance for laboratory-confirmed influenza in adults (≥16 years) hospitalized across Canada during the 2011–2014 influenza seasons. …”
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“…Training and testing were conducted using 5-fold cross validation. A class imbalance issue was addressed using a random subsampling of the training dataset. …”
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“…METHODS: This was a single‐center prospective study of DL(PA) conducted between May 2015 and June 2016 in northern France. …”
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“…BACKGROUND: Classroom-based stuttering intervention addressing negative peer attitudes, perceptions, teasing and bullying of children who stutter (CWS) is required as part of holistic stuttering management because of its occurrence in primary school. This study was conducted in 2017, in 10 primary schools in the Western Cape, South Africa within lower (second and third) and higher (fourth and fifth) quintiles. …”
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“…BACKGROUND: The C-terminal 42 kDa domain of Plasmodium knowlesi merozoite surface protein 1 (PkMSP1) is a potential asexual blood-stage vaccine candidate, however, only a limited number of clinical isolates have been analysed from Malaysia and no inter-country comparative diversity study has been conducted. In the present study, nucleotide diversity, haplotypes and natural selection levels of pkmsp1 in clinical samples from geographically distinct regions of Malaysia and Thailand were investigated. …”
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