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570221por Gomes, Marília B, Cobas, Roberta A, Matheus, Alessandra S, Tannus, Lucianne R, Negrato, Carlos Antonio, Rodacki, Melanie, Braga, Neuza, Cordeiro, Marilena M, Luescher, Jorge L, Berardo, Renata S, Nery, Marcia, Arruda-Marques, Maria do Carmo, Calliari, Luiz E, Noronha, Renata M, Manna, Thais D, Zajdenverg, Lenita, Salvodelli, Roberta, Penha, Fernanda G, Foss, Milton C, Foss-Freitas, Maria C, Pires, Antonio C, Robles, Fernando C, Guedes, MariadeFátimaS, Dib, Sergio A, Dualib, Patricia, Silva, Saulo C, Sepulvida, Janice, Almeida, Henriqueta G, Sampaio, Emerson, Rea, Rosangela, Faria, Ana Cristina R, Tschiedel, Balduino, Lavigne, Suzana, Cardozo, Gustavo A, Azevedo, Mirela J, Canani, Luis Henrique, Zucatti, Alessandra T, Coral, Marisa Helena C, Pereira, Daniela Aline, Araujo, Luiz Antonio, Tolentino, Monica, Pedrosa, Hermelinda C, Prado, Flaviane A, Rassi, Nelson, Araujo, Leticia B, Fonseca, Reine Marie C, Guedes, Alexis D, Matos, Odelissa S, Faria, Manuel, Azulay, Rossana, Forti, Adriana C, Façanha, Cristina, Montenegro, Ana Paula, Montenegro, Renan, Melo, Naira H, Rezende, Karla F, Ramos, Alberto, Felicio, João Sooares, Santos, Flavia M, Jezini, Deborah L, Cordeiro, Marilena M“…METHODS: This was a cross-sectional, multicenter study conducted from December 2008 to December 2010 in 28 secondary and tertiary care public clinics in 20 Brazilian cities in north/northeast, mid-west, southeast and south regions. …”
Publicado 2012
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570222por Archambault, Patrick M, van de Belt, Tom H, Grajales III, Francisco J, Faber, Marjan J, Kuziemsky, Craig E, Gagnon, Susie, Bilodeau, Andrea, Rioux, Simon, Nelen, Willianne LDM, Gagnon, Marie-Pierre, Turgeon, Alexis F, Aubin, Karine, Gold, Irving, Poitras, Julien, Eysenbach, Gunther, Kremer, Jan AM, Légaré, France“…A high prevalence of CWA use (ie, more than 50%) is reported in 58% (7/12) of surveys conducted with health care professionals and students. …”
Publicado 2013
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570223por Tardif, Jean-Claude, Ballantyne, Christie M., Barter, Philip, Dasseux, Jean-Louis, Fayad, Zahi A., Guertin, Marie-Claude, Kastelein, John J. P., Keyserling, Constance, Klepp, Heather, Koenig, Wolfgang, L'Allier, Philippe L., Lespérance, Jacques, Lüscher, Thomas F., Paolini, John F., Tawakol, Ahmed, Waters, David D., Pfeffer, M., Brown, V., Rouleau, J., Watkins, P., Wei, L.J., Gosselin, G., Chayer, C., Lanthier, S., Pelletier, G.B., Racine, N., Agarwal, H., Brilakis, E., Cannon, L., Carrié, D., Corbelli, J., Coste, P., de Winter, R., Diaz, A., Eisenberg, S., Ennis, B., Fajadet, J., Fam, N., Fortuin, D., Gessler, C., Grines, C., Guerra, D., Gum, H., Haldis, T., Heestermans, T., Herrman, J.P., Huynh, T., Kedhi, E., Koren, M., Kouz, S., Krolick, M., Kumkumian, G., Lavi, S., Li, R.J., Masud, ARZ, McAlhany, C., McGrew, F.A., O'Shaughnessy, C., Oude Ophuis, A.J.M., Parr, K., Penny, W., Pesant, Y., Post, H., Robinson, S., Rodes-Cabau, J., Roy, A., Schulman, S., Spence, F., Stouffer, G., Stys, T., Sussex, B., Tahirkheli, N., Tardif, J-C., Grégoire, J., ten Berg, J., van Boven, A.J., von Birgelen, C., Weinstein, D.“…DESIGN AND SETTING: A prospective, double-blinded, randomized trial was conducted at 51 centres in the USA, the Netherlands, Canada, and France. …”
Publicado 2014
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570224por Archambault, Patrick M, Turgeon, Alexis F, Witteman, Holly O, Lauzier, François, Moore, Lynne, Lamontagne, François, Horsley, Tanya, Gagnon, Marie-Pierre, Droit, Arnaud, Weiss, Matthew, Tremblay, Sébastien, Lachaine, Jean, Le Sage, Natalie, Émond, Marcel, Berthelot, Simon, Plaisance, Ariane, Lapointe, Jean, Razek, Tarek, van de Belt, Tom H, Brand, Kevin, Bérubé, Mélanie, Clément, Julien, Grajales III, Francisco Jose, Eysenbach, Gunther, Kuziemsky, Craig, Friedman, Debbie, Lang, Eddy, Muscedere, John, Rizoli, Sandro, Roberts, Derek J, Scales, Damon C, Sinuff, Tasnim, Stelfox, Henry T, Gagnon, Isabelle, Chabot, Christian, Grenier, Richard, Légaré, France“…A rapid, iterative prototyping process with 15 health professionals from nonparticipating centers will allow us to identify and resolve usability issues prior to finalizing the definitive version for the interrupted time series. Second, we will conduct an interrupted time series to measure the impact of our combined intervention on the quality of care in four trauma centers that will be selected—one level I, one level II, and two level III centers. …”
Publicado 2015
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570225por Yingling, Leah R, Brooks, Alyssa T, Wallen, Gwenyth R, Peters-Lawrence, Marlene, McClurkin, Michael, Cooper-McCann, Rebecca, Wiley Jr, Kenneth L, Mitchell, Valerie, Saygbe, Johnetta N, Johnson, Twanda D, Curry, Rev. Kendrick E, Johnson, Allan A, Graham, Avis P, Graham, Lennox A, Powell-Wiley, Tiffany M“…At the recommendation of D.C. CHOC members, we conducted a focus group and piloted the proposed PA-monitoring system with community members representing churches that would be targeted by the Cardiovascular Health and Needs Assessment. …”
Publicado 2016
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570226por Samartzis, Dino, Cheung, Jason Pui Yin, Rajasekaran, Shanmuganathan, Kawaguchi, Yoshiharu, Acharya, Shankar, Kawakami, Mamoru, Satoh, Shigenobu, Chen, Wen-Jer, Park, Chun-Kun, Lee, Chong-Suh, Foocharoen, Thanit, Nagashima, Hideki, Kuh, Sunguk, Zheng, Zhaomin, Condor, Richard, Ito, Manabu, Iwasaki, Motoki, Jeong, Je Hoon, Luk, Keith D. K., Prijambodo, Bambang, Rege, Amol, Jahng, Tae-Ahn, Luo, Zhuojing, Tassanawipas, Warat/Anant, Acharya, Narayana, Pokharel, Rohit, Shen, Yong, Ito, Takui, Zhang, Zhihai, Aithala P., Janardhana, Kumar, Gomatam Vijay, Jabir, Rahyussalim Ahmad, Basu, Saumyajit, Li, Baojun, Moudgil, Vishal, Goss, Ben, Sham, Phoebe, Williams, Richard“…CONCLUSIONS: To the authors’ knowledge, this is one of the largest studies conducted, in particular in an Asian population, addressing facet joint tropism. …”
Publicado 2016
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570227por Kochar, Bharati, Aldridge, Molly, Cook, Suzanne Follan, Bright, Renee, Mallette, Meaghan, Moniz, Heather, Shah, Samir A, LeLeiko, Neal S, Shapiro, Jason, Sands, Bruce E, Chen, Wenli, Jaeger, Elizabeth, Galanko, Joseph, Long, Millie D, Martin, Christopher F, Sandler, Robert S, Kappelman, Michael D“…Overcoming this barrier will be needed to generate meaningful sample sizes to conduct studies of biomarkers, natural history, and clinical effectiveness using linked data.…”
Publicado 2016
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570228por Guo, Yan, Warren Andersen, Shaneda, Shu, Xiao-Ou, Michailidou, Kyriaki, Bolla, Manjeet K., Wang, Qin, Garcia-Closas, Montserrat, Milne, Roger L., Schmidt, Marjanka K., Chang-Claude, Jenny, Dunning, Allison, Bojesen, Stig E., Ahsan, Habibul, Aittomäki, Kristiina, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Beckmann, Matthias W., Beeghly-Fadiel, Alicia, Benitez, Javier, Bogdanova, Natalia V., Bonanni, Bernardo, Børresen-Dale, Anne-Lise, Brand, Judith, Brauch, Hiltrud, Brenner, Hermann, Brüning, Thomas, Burwinkel, Barbara, Casey, Graham, Chenevix-Trench, Georgia, Couch, Fergus J., Cox, Angela, Cross, Simon S., Czene, Kamila, Devilee, Peter, Dörk, Thilo, Dumont, Martine, Fasching, Peter A., Figueroa, Jonine, Flesch-Janys, Dieter, Fletcher, Olivia, Flyger, Henrik, Fostira, Florentia, Gammon, Marilie, Giles, Graham G., Guénel, Pascal, Haiman, Christopher A., Hamann, Ute, Hooning, Maartje J., Hopper, John L., Jakubowska, Anna, Jasmine, Farzana, Jenkins, Mark, John, Esther M., Johnson, Nichola, Jones, Michael E., Kabisch, Maria, Kibriya, Muhammad, Knight, Julia A., Koppert, Linetta B., Kosma, Veli-Matti, Kristensen, Vessela, Le Marchand, Loic, Lee, Eunjung, Li, Jingmei, Lindblom, Annika, Luben, Robert, Lubinski, Jan, Malone, Kathi E., Mannermaa, Arto, Margolin, Sara, Marme, Frederik, McLean, Catriona, Meijers-Heijboer, Hanne, Meindl, Alfons, Neuhausen, Susan L., Nevanlinna, Heli, Neven, Patrick, Olson, Janet E., Perez, Jose I. A., Perkins, Barbara, Peterlongo, Paolo, Phillips, Kelly-Anne, Pylkäs, Katri, Rudolph, Anja, Santella, Regina, Sawyer, Elinor J., Schmutzler, Rita K., Seynaeve, Caroline, Shah, Mitul, Shrubsole, Martha J., Southey, Melissa C., Swerdlow, Anthony J., Toland, Amanda E., Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Ursin, Giske, Van Der Luijt, Rob B., Verhoef, Senno, Whittemore, Alice S., Winqvist, Robert, Zhao, Hui, Zhao, Shilin, Hall, Per, Simard, Jacques, Kraft, Peter, Pharoah, Paul, Hunter, David, Easton, Douglas F., Zheng, Wei“…Because most studies measured BMI after cancer diagnosis, we could not conduct a parallel analysis to adequately evaluate the association of measured BMI with breast cancer risk prospectively. …”
Publicado 2016
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570229por van der Meij, Eva, Huirne, Judith AF, Bouwsma, Esther VA, van Dongen, Johanna M, Terwee, Caroline B, van de Ven, Peter M, den Bakker, Chantal M, van der Meij, Suzan, van Baal, W Marchien, Leclercq, Wouter KG, Geomini, Peggy MAJ, Consten, Esther CJ, Schraffordt Koops, Steven E, van Kesteren, Paul JM, Stockmann, Hein BAC, ten Cate, A Dorien, Davids, Paul HP, Scholten, Petrus C, van den Heuvel, Baukje, Schaafsma, Frederieke G, Meijerink, Wilhelmus JHJ, Bonjer, H Jaap, Anema, Johannes R“…All statistical analyses will be conducted according to the intention-to-treat principle. …”
Publicado 2016
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570230por Rello, Jordi, Krenn, Claus-Georg, Locker, Gottfried, Pilger, Ernst, Madl, Christian, Balica, Laura, Dugernier, Thierry, Laterre, Pierre-Francois, Spapen, Herbert, Depuydt, Pieter, Vincent, Jean-Louis, Bogár, Lajos, Szabó, Zsuzsanna, Völgyes, Barbara, Máñez, Rafael, Cakar, Nahit, Ramazanoglu, Atilla, Topeli, Arzu, Mastruzzo, Maria A., Jasovich, Abel, Remolif, Christian G., del Carmen Soria, Liliana, Andresen Hernandez, Max A., Ruiz Balart, Carolina, Krémer, Ildikó, Molnár, Zsolt, von Sonnenburg, Frank, Lyons, Arthur, Joannidis, Michael, Burgmann, Heinz, Welte, Tobias, Klingler, Anton, Hochreiter, Romana, Westritschnig, Kerstin“…In order to assess the immunogenicity and safety of IC43 in patients who are most at risk of acquiring Pseudomonas infections, it was evaluated in mechanically ventilated ICU patients. METHODS: We conducted a randomized, placebo-controlled, partially blinded study in mechanically ventilated ICU patients. …”
Publicado 2017
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570231por Phu, Vu Dinh, Nadjm, Behzad, Duy, Nguyen Hoang Anh, Co, Dao Xuan, Mai, Nguyen Thi Hoang, Trinh, Dao Tuyet, Campbell, James, Khiem, Dong Phu, Quang, Tran Ngoc, Loan, Huynh Thi, Binh, Ha Son, Dinh, Quynh-Dao, Thuy, Duong Bich, Lan, Huong Nguyen Phu, Ha, Nguyen Hong, Bonell, Ana, Larsson, Mattias, Hoan, Hoang Minh, Tuan, Đang Quoc, Hanberger, Hakan, Minh, Hoang Nguyen Van, Yen, Lam Minh, Van Hao, Nguyen, Binh, Nguyen Gia, Chau, Nguyen Van Vinh, Van Kinh, Nguyen, Thwaites, Guy E., Wertheim, Heiman F., van Doorn, H. Rogier, Thwaites, C. Louise“…Data from these settings are vital to plan preventative interventions and assess their cost-effectiveness, but few are available. METHODS: We conducted a prospective observational study in four Vietnamese ICUs to assess the incidence and impact of VARI. …”
Publicado 2017
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570232por Nishida, Osamu, Ogura, Hiroshi, Egi, Moritoki, Fujishima, Seitaro, Hayashi, Yoshiro, Iba, Toshiaki, Imaizumi, Hitoshi, Inoue, Shigeaki, Kakihana, Yasuyuki, Kotani, Joji, Kushimoto, Shigeki, Masuda, Yoshiki, Matsuda, Naoyuki, Matsushima, Asako, Nakada, Taka-aki, Nakagawa, Satoshi, Nunomiya, Shin, Sadahiro, Tomohito, Shime, Nobuaki, Yatabe, Tomoaki, Hara, Yoshitaka, Hayashida, Kei, Kondo, Yutaka, Sumi, Yuka, Yasuda, Hideto, Aoyama, Kazuyoshi, Azuhata, Takeo, Doi, Kent, Doi, Matsuyuki, Fujimura, Naoyuki, Fuke, Ryota, Fukuda, Tatsuma, Goto, Koji, Hasegawa, Ryuichi, Hashimoto, Satoru, Hatakeyama, Junji, Hayakawa, Mineji, Hifumi, Toru, Higashibeppu, Naoki, Hirai, Katsuki, Hirose, Tomoya, Ide, Kentaro, Kaizuka, Yasuo, Kan’o, Tomomichi, Kawasaki, Tatsuya, Kuroda, Hiromitsu, Matsuda, Akihisa, Matsumoto, Shotaro, Nagae, Masaharu, Onodera, Mutsuo, Ohnuma, Tetsu, Oshima, Kiyohiro, Saito, Nobuyuki, Sakamoto, So, Sakuraya, Masaaki, Sasano, Mikio, Sato, Norio, Sawamura, Atsushi, Shimizu, Kentaro, Shirai, Kunihiro, Takei, Tetsuhiro, Takeuchi, Muneyuki, Takimoto, Kohei, Taniguchi, Takumi, Tatsumi, Hiroomi, Tsuruta, Ryosuke, Yama, Naoya, Yamakawa, Kazuma, Yamashita, Chizuru, Yamashita, Kazuto, Yoshida, Takeshi, Tanaka, Hiroshi, Oda, Shigeto“…The approval rate obtained through committee voting, in addition to ratings of the strengths of the recommendation, and its supporting evidence were also added to each recommendation statement. We conducted meta-analyses for 29 CQs. Thirty-seven CQs contained recommendations in the form of an expert consensus due to insufficient evidence. …”
Publicado 2018
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570233por Tagge, Chad A, Fisher, Andrew M, Minaeva, Olga V, Gaudreau-Balderrama, Amanda, Moncaster, Juliet A, Zhang, Xiao-Lei, Wojnarowicz, Mark W, Casey, Noel, Lu, Haiyan, Kokiko-Cochran, Olga N, Saman, Sudad, Ericsson, Maria, Onos, Kristen D, Veksler, Ronel, Senatorov, Vladimir V, Kondo, Asami, Zhou, Xiao Z, Miry, Omid, Vose, Linnea R, Gopaul, Katisha R, Upreti, Chirag, Nowinski, Christopher J, Cantu, Robert C, Alvarez, Victor E, Hildebrandt, Audrey M, Franz, Erich S, Konrad, Janusz, Hamilton, James A, Hua, Ning, Tripodis, Yorghos, Anderson, Andrew T, Howell, Gareth R, Kaufer, Daniela, Hall, Garth F, Lu, Kun P, Ransohoff, Richard M, Cleveland, Robin O, Kowall, Neil W, Stein, Thor D, Lamb, Bruce T, Huber, Bertrand R, Moss, William C, Friedman, Alon, Stanton, Patric K, McKee, Ann C, Goldstein, Lee E“…These pathologies were also accompanied by early, persistent, and bilateral impairment in axonal conduction velocity in the hippocampus and defective long-term potentiation of synaptic neurotransmission in the medial prefrontal cortex, brain regions distant from acute brain injury. …”
Publicado 2018
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570234por Traore, Mohamad M., Junnila, Amy, Traore, Sekou F., Doumbia, Seydou, Revay, Edita E., Kravchenko, Vasiliy D., Schlein, Yosef, Arheart, Kristopher L., Gergely, Petrányi, Xue, Rui-De, Hausmann, Axel, Beck, Robert, Prozorov, Alex, Diarra, Rabiatou A., Kone, Aboubakr S., Majambere, Silas, Bradley, John, Vontas, John, Beier, John C., Müller, Günter C.“…METHODS: A 2-day field experiment was conducted to determine the number of mosquitoes feeding on natural sugar versus those feeding on bait stations containing attractive sugar bait without toxin (ASB)—but with food dye. …”
Publicado 2020
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570235por Sombié, Herman Karim, Sorgho, Abel Pegdwendé, Kologo, Jonas Koudougou, Ouattara, Abdoul Karim, Yaméogo, Sakinata, Yonli, Albert Théophane, Djigma, Florencia Wendkuuni, Tchelougou, Daméhan, Somda, Dogfounianalo, Kiendrébéogo, Isabelle Touwendpoulimdé, Bado, Prosper, Nagalo, Bolni Marius, Nagabila, Youssoufou, Adoko, Enagnon Tiémoko Herman Donald, Zabsonré, Patrice, Millogo, Hassanata, Simporé, Jacques“…In the present study, we characterize the null genotypes of GSTM1 and GSTT1 in order to investigate the association between them and the risk of developing essential hypertension. METHODS: We conducted a case-control study in Burkina Faso, including 245 subjects with essential hypertension as case and 269 control subjects with normal blood pressure. …”
Publicado 2020
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570236por Knight, Stephen R, Ho, Antonia, Pius, Riinu, Buchan, Iain, Carson, Gail, Drake, Thomas M, Dunning, Jake, Fairfield, Cameron J, Gamble, Carrol, Green, Christopher A, Gupta, Rishi, Halpin, Sophie, Hardwick, Hayley E, Holden, Karl A, Horby, Peter W, Jackson, Clare, Mclean, Kenneth A, Merson, Laura, Nguyen-Van-Tam, Jonathan S, Norman, Lisa, Noursadeghi, Mahdad, Olliaro, Piero L, Pritchard, Mark G, Russell, Clark D, Shaw, Catherine A, Sheikh, Aziz, Solomon, Tom, Sudlow, Cathie, Swann, Olivia V, Turtle, Lance CW, Openshaw, Peter JM, Baillie, J Kenneth, Semple, Malcolm G, Docherty, Annemarie B, Harrison, Ewen M, Baillie, J Kenneth, Semple, Malcolm G, Openshaw, Peter JM, Carson, Gail, Alex, Beatrice, Bach, Benjamin, Barclay, Wendy S, Bogaert, Debby, Chand, Meera, Cooke, Graham S, Docherty, Annemarie B, Dunning, Jake, da Silva Filipe, Ana, Fletcher, Tom, Green, Christopher A, Harrison, Ewen M, Hiscox, Julian A, Ho, Antonia Ying Wai, Horby, Peter W, Ijaz, Samreen, Khoo, Saye, Klenerman, Paul, Law, Andrew, Lim, Wei Shen, Mentzer, Alexander J, Merson, Laura, Meynert, Alison M, Noursadeghi, Mahdad, Moore, Shona C, Palmarini, Massimo, Paxton, William A, Pollakis, Georgios, Price, Nicholas, Rambaut, Andrew, Robertson, David L, Russell, Clark D, Sancho-Shimizu, Vanessa, Scott, Janet T, Sigfrid, Louise, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Summers, Charlotte, Tedder, Richard S, Thomson, Emma C, Thwaites, Ryan S, Turtle, Lance CW, Zambon, Maria, Hardwick, Hayley, Donohue, Chloe, Ewins, Jane, Oosthuyzen, Wilna, Griffiths, Fiona, Norman, Lisa, Pius, Riinu, Drake, Tom M, Fairfield, Cameron J, Knight, Stephen, Mclean, Kenneth A, Murphy, Derek, Shaw, Catherine A, Dalton, Jo, Girvan, Michelle, Saviciute, Egle, Roberts, Stephanie, Harrison, Janet, Marsh, Laura, Connor, Marie, Halpin, Sophie, Jackson, Clare, Gamble, Carrol, Leeming, Gary, Law, Andrew, Hendry, Ross, Scott-Brown, James, Greenhalf, William, Shaw, Victoria, McDonald, Sarah, Ahmed, Katie A, Armstrong, Jane A, Ashworth, Milton, Asiimwe, Innocent G, Bakshi, Siddharth, Barlow, Samantha L, Booth, Laura, Brennan, Benjamin, Bullock, Katie, Catterall, Benjamin WA, Clark, Jordan J, Clarke, Emily A, Cole, Sarah, Cooper, Louise, Cox, Helen, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Dyer, Philip, Elliott, Angela, Evans, Anthony, Fisher, Lewis WS, Foster, Terry, Garcia-Dorival, Isabel, Greenhalf, Willliam, Gunning, Philip, Hartley, Catherine, Ho, Antonia, Jensen, Rebecca L, Jones, Christopher B, Jones, Trevor R, Khandaker, Shadia, King, Katharine, Kiy, Robyn T, Koukorava, Chrysa, Lake, Annette, Lant, Suzannah, Latawiec, Diane, Lavelle-Langham, L, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, McDonald, Sarah, McEvoy, Laurence, McLauchlan, John, Metelmann, Soeren, Miah, Nahida S, Middleton, Joanna, Mitchell, Joyce, Moore, Shona C, Murphy, Ellen G, Penrice-Randal, Rebekah, Pilgrim, Jack, Prince, Tessa, Reynolds, Will, Ridley, P Matthew, Sales, Debby, Shaw, Victoria E, Shears, Rebecca K, Small, Benjamin, Subramaniam, Krishanthi S, Szemiel, Agnieska, Taggart, Aislynn, Tanianis-Hughes, Jolanta, Thomas, Jordan, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Zhang, J Eunice, Adeniji, Kayode, Agranoff, Daniel, Agwuh, Ken, Ail, Dhiraj, Alegria, Ana, Angus, Brian, Ashish, Abdul, Atkinson, Dougal, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Barrett, Nicholas, Bassford, Christopher, Baxter, David, Beadsworth, Michael, Bernatoniene, Jolanta, Berridge, John, Best, Nicola, Bothma, Pieter, Brealey, David, Brittain-Long, Robin, Bulteel, Naomi, Burden, Tom, Burtenshaw, Andrew, Caruth, Vikki, Chadwick, David, Chambler, Duncan, Chee, Nigel, Child, Jenny, Chukkambotla, Srikanth, Clark, Tom, Collini, Paul, Cosgrove, Catherine, Cupitt, Jason, Cutino-Moguel, Maria-Teresa, Dark, Paul, Dawson, Chris, Dervisevic, Samir, Donnison, Phil, Douthwaite, Sam, DuRand, Ingrid, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Eziefula, Chi, Fegan, Chrisopher, Finn, Adam, Fullerton, Duncan, Garg, Sanjeev, Garg, Sanjeev, Garg, Atul, Godden, Jo, Goldsmith, Arthur, Graham, Clive, Hardy, Elaine, Hartshorn, Stuart, Harvey, Daniel, Havalda, Peter, Hawcutt, Daniel B, Hobrok, Maria, Hodgson, Luke, Holme, Anita, Hormis, Anil, Jacobs, Michael, Jain, Susan, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Kegg, Stephen, Kelsey, Michael, Kendall, Jason, Kerrison, Caroline, Kerslake, Ian, Koch, Oliver, Koduri, Gouri, Koshy, George, Laha, Shondipon, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, Limb, James, Linnett, Vanessa, Little, Jeff, MacMahon, Michael, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, Matovu, Elijah, McCullough, Katherine, McEwen, Ruth, Meda, Manjula, Mills, Gary, Minton, Jane, Mirfenderesky, Mariyam, Mohandas, Kavya, Mok, Quen, Moon, James, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Mortimore, Katherine, Moses, Samuel, Mpenge, Mbiye, Mulla, Rohinton, Murphy, Michael, Nagel, Megan, Nagarajan, Thapas, Nelson, Mark, Otahal, Igor, Pais, Mark, Panchatsharam, Selva, Paraiso, Hassan, Patel, Brij, Pepperell, Justin, Peters, Mark, Phull, Mandeep, Pintus, Stefania, Pooni, Jagtur Singh, Post, Frank, Price, David, Prout, Rachel, Rae, Nikolas, Reschreiter, Henrik, Reynolds, Tim, Richardson, Neil, Roberts, Mark, Roberts, Devender, Rose, Alistair, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shah, Aarti, Shanmuga, Prad, Sharma, Anil, Shawcross, Anna, Sizer, Jeremy, Smith, Richard, Snelson, Catherine, Spittle, Nick, Staines, Nikki, Stambach, Tom, Stewart, Richard, Subudhi, Pradeep, Szakmany, Tamas, Tatham, Kate, Thomas, Jo, Thompson, Chris, Thompson, Robert, Tridente, Ascanio, Tupper-Carey, Darell, Twagira, Mary, Ustianowski, Andrew, Vallotton, Nick, Vincent-Smith, Lisa, Visuvanathan, Shico, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Walden, Andrew, Welters, Ingeborg, Whitehouse, Tony, Whittaker, Paul, Whittington, Ashley, Wijesinghe, Meme, Williams, Martin, Wilson, Lawrence, Wilson, Sarah, Winchester, Stephen, Wiselka, Martin, Wolverson, Adam, Wooton, Daniel G, Workman, Andrew, Yates, Bryan, Young, Peter“…Model training was performed on a cohort of patients recruited between 6 February and 20 May 2020, with validation conducted on a second cohort of patients recruited after model development between 21 May and 29 June 2020. …”
Publicado 2020
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570237por Cao, Bin, Wang, Yeming, Wen, Danning, Liu, Wen, Wang, Jingli, Fan, Guohui, Ruan, Lianguo, Song, Bin, Cai, Yanping, Wei, Ming, Li, Xingwang, Xia, Jiaan, Chen, Nanshan, Xiang, Jie, Yu, Ting, Bai, Tao, Xie, Xuelei, Zhang, Li, Li, Caihong, Yuan, Ye, Chen, Hua, Li, Huadong, Huang, Hanping, Tu, Shengjing, Gong, Fengyun, Liu, Ying, Wei, Yuan, Dong, Chongya, Zhou, Fei, Gu, Xiaoying, Xu, Jiuyang, Liu, Zhibo, Zhang, Yi, Li, Hui, Shang, Lianhan, Wang, Ke, Li, Kunxia, Zhou, Xia, Dong, Xuan, Qu, Zhaohui, Lu, Sixia, Hu, Xujuan, Ruan, Shunan, Luo, Shanshan, Wu, Jing, Peng, Lu, Cheng, Fang, Pan, Lihong, Zou, Jun, Jia, Chunmin, Wang, Juan, Liu, Xia, Wang, Shuzhen, Wu, Xudong, Ge, Qin, He, Jing, Zhan, Haiyan, Qiu, Fang, Guo, Li, Huang, Chaolin, Jaki, Thomas, Hayden, Frederick G., Horby, Peter W., Zhang, Dingyu, Wang, Chen“…BACKGROUND: No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV-2. METHODS: We conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao(2)) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxygen (Pao(2)) to the fraction of inspired oxygen (Fio(2)) of less than 300 mm Hg. …”
Publicado 2020
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570238por Murphy, Neil, Carreras-Torres, Robert, Song, Mingyang, Chan, Andrew T., Martin, Richard M., Papadimitriou, Nikos, Dimou, Niki, Tsilidis, Konstantinos K., Banbury, Barbara, Bradbury, Kathryn E., Besevic, Jelena, Rinaldi, Sabina, Riboli, Elio, Cross, Amanda J., Travis, Ruth C., Agnoli, Claudia, Albanes, Demetrius, Berndt, Sonja I., Bézieau, Stéphane, Bishop, D. Timothy, Brenner, Hermann, Buchanan, Daniel D., Onland-Moret, N. Charlotte, Burnett-Hartman, Andrea, Campbell, Peter T., Casey, Graham, Castellví-Bel, Sergi, Chang-Claude, Jenny, Chirlaque, María-Dolores, de la Chapelle, Albert, English, Dallas, Figueiredo, Jane C., Gallinger, Steven J., Giles, Graham G., Gruber, Stephen B., Gsur, Andrea, Hampe, Jochen, Hampel, Heather, Harrison, Tabitha A., Hoffmeister, Michael, Hsu, Li, Huang, Wen-Yi, Huyghe, Jeroen R., Jenkins, Mark A., Keku, Temitope O., Kühn, Tilman, Kweon, Sun-Seog, Le Marchand, Loic, Li, Christopher I., Li, Li, Lindblom, Annika, Martín, Vicente, Milne, Roger L., Moreno, Victor, Newcomb, Polly A., Offit, Kenneth, Ogino, Shuji, Ose, Jennifer, Perduca, Vittorio, Phipps, Amanda I., Platz, Elizabeth A., Potter, John D., Qu, Conghui, Rennert, Gad, Sakoda, Lori C., Schafmayer, Clemens, Schoen, Robert E., Slattery, Martha L., Tangen, Catherine M., Ulrich, Cornelia M., van Duijnhoven, Franzel J.B., Van Guelpen, Bethany, Visvanathan, Kala, Vodicka, Pavel, Vodickova, Ludmila, Vymetalkova, Veronika, Wang, Hansong, White, Emily, Wolk, Alicja, Woods, Michael O., Wu, Anna H., Zheng, Wei, Peters, Ulrike, Gunter, Marc J.“…BACKGROUND & AIMS: Human studies examining associations between circulating levels of insulin-like growth factor 1 (IGF1) and insulin-like growth factor binding protein 3 (IGFBP3) and colorectal cancer risk have reported inconsistent results. We conducted complementary serologic and Mendelian randomization (MR) analyses to determine whether alterations in circulating levels of IGF1 or IGFBP3 are associated with colorectal cancer development. …”
Publicado 2020
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570239por Su, Jinmei, Li, Mengtao, He, Lan, Zhao, Dongbao, Wan, Weiguo, Liu, Yi, Xu, Jianhua, Xu, Jian, Liu, Huaxiang, Jiang, Lindi, Wu, Huaxiang, Zuo, Xiaoxia, Huang, Cibo, Liu, Xiumei, Li, Fen, Zhang, Zhiyi, Liu, Xiangyuan, Dong, Lingli, Li, Tianwang, Chen, Haiying, Li, Jingyang, He, Dongyi, Lu, Xin, Huang, Anbin, Tao, Yi, Wang, Yanyan, Zhang, Zhuoli, Wei, Wei, Li, Xiaofeng, Zeng, Xiaofeng“…METHODS: A multicenter, randomized, double-blind, parallel, positive control, phase III clinical trial was conducted at 28 locations in China. Patients with active ankylosing spondylitis were randomized in a 2:1 ratio to subcutaneously receive 40 mg of either HS016 or adalimumab every other week for 24 weeks. …”
Publicado 2020
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570240por Gallagher, Emily J., Fei, Kezhen, Feldman, Sheldon M., Port, Elisa, Friedman, Neil B., Boolbol, Susan K., Killelea, Brigid, Pilewskie, Melissa, Choi, Lydia, King, Tari, Nayak, Anupma, Franco, Rebeca, Cruz, Daliz, Antoniou, Irini M., LeRoith, Derek, Bickell, Nina A.“…We aimed to determine whether insulin resistance mediates in part the association between race and breast cancer prognosis, and if insulin receptor (IR) and insulin-like growth factor receptor (IGF-1R) expression differs between tumors from Black and White women. METHODS: We conducted a cross-sectional, multi-center study across ten hospitals. …”
Publicado 2020
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